Zobrazeno 1 - 10
of 133
pro vyhledávání: '"Igor, Letovanec"'
Autor:
Gaylor Boulay, Liliane C. Broye, Rui Dong, Sowmya Iyer, Rajendran Sanalkumar, Yu-Hang Xing, Rémi Buisson, Shruthi Rengarajan, Beverly Naigles, Benoît Duc, Angela Volorio, Mary E. Awad, Raffaele Renella, Ivan Chebib, G. Petur Nielsen, Edwin Choy, Gregory M. Cote, Lee Zou, Igor Letovanec, Ivan Stamenkovic, Miguel N. Rivera, Nicolò Riggi
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract EWS fusion oncoproteins underlie several human malignancies including Desmoplastic Small Round Cell Tumor (DSRCT), an aggressive cancer driven by EWS-WT1 fusion proteins. Here we combine chromatin occupancy and 3D profiles to identify EWS-WT
Externí odkaz:
https://doaj.org/article/fd00253648764577aeb52739a580a6a3
Autor:
Deborah Wernly, Charles Beniere, Valerie Besse, Stephanie Seidler, Regine Lachat, Igor Letovanec, Daniela Huber, Colin Simonson
Publikováno v:
Life, Vol 14, Iss 2, p 204 (2024)
In Switzerland, breast cancer is the leading cancer among women, with breast-conserving surgery (BCS) being the preferred treatment for small tumors. The margin status post-surgery is a critical predictor of local recurrence. Achieving negative margi
Externí odkaz:
https://doaj.org/article/75316a30722f4a1b821b680bb3e8fa44
Autor:
Emely Möller, Viviane Praz, Sanalkumar Rajendran, Rui Dong, Alexandra Cauderay, Yu-Hang Xing, Lukuo Lee, Carlo Fusco, Liliane C. Broye, Luisa Cironi, Sowmya Iyer, Shruthi Rengarajan, Mary E. Awad, Beverly Naigles, Igor Letovanec, Nicola Ormas, Giovanna Finzi, Stefano La Rosa, Fausto Sessa, Ivan Chebib, G. Petur Nielsen, Antonia Digklia, Dimitrios Spentzos, Gregory M. Cote, Edwin Choy, Martin Aryee, Ivan Stamenkovic, Gaylor Boulay, Miguel N. Rivera, Nicolò Riggi
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
The relationship between cellular histogenesis and molecular phenotypes for the EWSR1- ATF1 fusion in clear cell sarcoma (CCS) requires further characterization. Here, the authors investigate the EWSR1-ATF1 gene regulation networks in CCS cell lines,
Externí odkaz:
https://doaj.org/article/1755fdc1556a4ae2aea83d025041fcd5
Autor:
Laureline, Wetterwald, Patrick, Omoumi, Tu, Nguyen, Stephane, Cherix, Ana, Dolcan, Daniela, Ferraro, Chiara, Saglietti, Igor, Letovanec, Antonia, Digklia
Publikováno v:
Skeletal Radiology; Nov2024, Vol. 53 Issue 11, p2537-2543, 7p
Autor:
Wambaka Ange Mampuya, Hasna Bouchaab, Niklaus Schaefer, Remy Kinj, Stefano La Rosa, Igor Letovanec, Mahmut Ozsahin, Jean Bourhis, George Coukos, Solange Peters, Fernanda G. Herrera
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 27, Iss , Pp 85-88 (2021)
The abscopal effect describes the ability of locally administered radiotherapy to induce systemic antitumor effects. Although mentioned for the first time in the 1950s, records of abscopal effects, considered to be immune-mediated, are scarce with ra
Externí odkaz:
https://doaj.org/article/66a65e42bdd24c36a0fed917c4dfb384
Autor:
Flavian Tabotta, Gilbert R. Ferretti, Helmut Prosch, Samia Boussouar, Anne-Laure Brun, Justus E. Roos, Lukas Ebner, Igor Letovanec, Michel Brauner, Catherine Beigelman-Aubry
Publikováno v:
Insights into Imaging, Vol 11, Iss 1, Pp 1-12 (2020)
Abstract Acute or chronic non-neoplastic diffuse mediastinal diseases have multiple causes, degrees of severity, and a wide range of management. Some situations require emergency care while others do not need specific treatment. Although the diagnosi
Externí odkaz:
https://doaj.org/article/c14f8ca018eb4acca72aca5579b196a9
Autor:
Georgios Gkagkalis, Kevin Moerenhout, Hannes A. Rüdiger, Daniel A. Müller, Igor Letovanec, Stephane Cherix
Publikováno v:
Case Reports in Orthopedics, Vol 2021 (2021)
Primary tumors of the pelvis are considered difficult to treat due to the complex anatomy and the proximity of important neurovascular structures. The surgical armamentarium for the treatment of these tumors has evolved with the help of cutting-edge
Externí odkaz:
https://doaj.org/article/c4ac598cf5a74a6b8920d2f926475a08
Autor:
Chiara Pozzessere, Hasna Bouchaab, Raphael Jumeau, Igor Letovanec, Cécile Daccord, Jean Bourhis, John O. Prior, Solange Peters, Romain Lazor, Catherine Beigelman-Aubry
Publikováno v:
ERJ Open Research, Vol 6, Iss 1 (2020)
In patients with primary or secondary lung tumour treated with immune checkpoint inhibitors, immune-related pneumonitis is a rare adverse event but may evolve to respiratory failure. Prompt management is required and usually consists of treatment int
Externí odkaz:
https://doaj.org/article/163ff949aa96444190e17ed7684067a5
Autor:
Giulia Fregni, Mathieu Quinodoz, Emely Möller, Joanna Vuille, Sabine Galland, Carlo Fusco, Patricia Martin, Igor Letovanec, Paolo Provero, Carlo Rivolta, Nicolo Riggi, Ivan Stamenkovic
Publikováno v:
EBioMedicine, Vol 29, Iss , Pp 128-145 (2018)
Metastasis is a multi-step process in which direct crosstalk between cancer cells and their microenvironment plays a key role. Here, we assessed the effect of paired tumor-associated and normal lung tissue mesenchymal stem cells (MSCs) on the growth
Externí odkaz:
https://doaj.org/article/059220043c5444d19f0e556e35c8798d
Autor:
Christoforos Astaras, Claudio De Vito, Prasad Chaskar, Aurelie Bornand, Kaouthar Khanfir, Amedeo Sciarra, Igor Letovanec, Claudia Corro, Pierre-Yves Dietrich, Petros Tsantoulis, Thibaud Koessler
Publikováno v:
Journal of Gastroenterology. 58:125-134
Background Rectal cancers represent 35% of colorectal cancers; 90% are adenocarcinomas, while squamous cell carcinoma accounts for 0.3% of them. Given its rarity, little is known concerning its pathogenesis, molecular profile and therapeutic manageme