Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Igor, Landais"'
Autor:
Sara Botto, Jinu Abraham, Nobuyo Mizuno, Kara Pryke, Bryan Gall, Igor Landais, Daniel N. Streblow, Klaus J. Fruh, Victor R. DeFilippis
Publikováno v:
mBio, Vol 10, Iss 1 (2019)
ABSTRACT Secretion of interleukin-1β (IL-1β) represents a fundamental innate immune response to microbial infection that, at the molecular level, occurs following activation of proteolytic caspases that cleave the immature protein into a secretable
Externí odkaz:
https://doaj.org/article/a95aa84d8b4242769d2b7f127e460ec9
Autor:
Lindsey B. Crawford, Jung Heon Kim, Donna Collins-McMillen, Byeong-Jae Lee, Igor Landais, Christine Held, Jay A. Nelson, Andrew D. Yurochko, Patrizia Caposio
Publikováno v:
mBio, Vol 9, Iss 2 (2018)
ABSTRACT The ability of human cytomegalovirus (HCMV) to reactivate from latent infection of hematopoietic progenitor cells (HPCs) is intimately linked to cellular differentiation. HCMV encodes UL7 that our group has shown is secreted from infected ce
Externí odkaz:
https://doaj.org/article/e112ec564a7b40c191ff06dc9080fbc1
Human Cytomegalovirus miR-UL112-3p Targets TLR2 and Modulates the TLR2/IRAK1/NFκB Signaling Pathway.
Autor:
Igor Landais, Chantel Pelton, Daniel Streblow, Victor DeFilippis, Shannon McWeeney, Jay A Nelson
Publikováno v:
PLoS Pathogens, Vol 11, Iss 5, p e1004881 (2015)
Human Cytomegalovirus (HCMV) encodes multiple microRNAs (miRNAs) whose functions are just beginning to be uncovered. Using in silico approaches, we identified the Toll-Like Receptor (TLR) innate immunity pathway as a possible target of HCMV miRNAs. L
Externí odkaz:
https://doaj.org/article/18dec7fffc8246b48fa924372a338c03
Autor:
Nicole L, Diggins, Lindsey B, Crawford, Hillary M, Struthers, Lauren M, Hook, Igor, Landais, Rebecca L, Skalsky, Meaghan H, Hancock
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2244
microRNAs (miRNAs) are small noncoding RNAs that regulate gene expression at the posttranscriptional level by binding to sites within the 3' untranslated regions of messenger RNA (mRNA) transcripts. The discovery of this completely new mechanism of g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::13b95f63d845c60c614c8f971afb7336
https://pubmed.ncbi.nlm.nih.gov/33555594
https://pubmed.ncbi.nlm.nih.gov/33555594
Autor:
Nicole L. Diggins, Lindsey B. Crawford, Hillary M. Struthers, Lauren M. Hook, Igor Landais, Rebecca L. Skalsky, Meaghan H. Hancock
Publikováno v:
Methods in Molecular Biology ISBN: 9781071611104
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f44eb3315ab63af1651e804ce585a39
https://doi.org/10.1007/978-1-0716-1111-1_16
https://doi.org/10.1007/978-1-0716-1111-1_16
Autor:
Kara M. Pryke, Sara Botto, Victor R. DeFilippis, Klaus Früh, Jinu Abraham, Bryan Gall, Nobuyo Mizuno, Igor Landais, Daniel N. Streblow
Publikováno v:
mBio
mBio, Vol 10, Iss 1, p e02510-18 (2019)
mBio, Vol 10, Iss 1 (2019)
mBio, Vol 10, Iss 1, p e02510-18 (2019)
mBio, Vol 10, Iss 1 (2019)
Persistent infection with HCMV is associated with the operation of diverse evasion phenotypes directed at antiviral immunity. Obstruction of intrinsic and innate immune responses is typically conferred by viral proteins either associated with the vir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09c451c735fef7c73cd4e50e5ae6b55d
https://pubmed.ncbi.nlm.nih.gov/30755509
https://pubmed.ncbi.nlm.nih.gov/30755509
Publikováno v:
Current Opinion in Virology. 7:40-46
The discovery that animals, plants and DNA viruses encode microRNAs (miRNAs) has transformed our understanding of the regulation of gene expression. miRNAs are ubiquitous small non-coding RNAs that regulate gene expression post-transcriptionally, gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d6d67001087396fc67bf5d61e002f6d
https://doi.org/10.1016/j.coviro.2014.03.015
https://doi.org/10.1016/j.coviro.2014.03.015
Autor:
Jay A. Nelson, Igor Landais
Publikováno v:
Current Opinion in Virology. 3:408-415
Cytomegalovirus (CMV) is a species-specific herpesvirus that is ubiquitous in the population and has the potential to cause significant disease in immunocompromised individuals as well as in congenitally infected infants. CMV establishes latency in c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71dad70fdf93faae92b9b1cfdb206792
https://doi.org/10.1016/j.coviro.2013.06.002
https://doi.org/10.1016/j.coviro.2013.06.002
Publikováno v:
International Journal of Cancer. 124:783-792
The Fanconi Anemia (FA) DNA damage response pathway is involved in the processing of DNA interstrand crosslinks (ICLs). As such, inhibition of the FA pathway could chemosensitize FA-competent tumor cells to commonly used ICL agents like cisplatin. Mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1888a5c8bb74ae0a2d1049534c24ffcf
https://doi.org/10.1002/ijc.24039
https://doi.org/10.1002/ijc.24039
Autor:
Igor Landais, Meliza Gutiérrez-Ayala, Humberto Mejía-Ruíz, Marie-Helene Ogliastro, Vania Serrano-Pinto, Alejandra García-Gasca, Celia Vazquez-Boucard, Humberto Villarreal-Colmenares
Publikováno v:
Molecular Reproduction and Development. 69:17-21
PCR products of 1.1 and 0.9 kb were generated using Cherax quadricarinatus genomic DNA in the first case, and hepatopancreas and ovary cDNAs in the second case. These PCR products were cloned and analyzed for nucleotide sequences. The 1.1 kb fragment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ecadcd306d85f0ae8272690d98a3e218
https://doi.org/10.1002/mrd.20157
https://doi.org/10.1002/mrd.20157