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Questioning the radiation limits of life: Ignicoccus hospitalis between replication and VBNC

Autor: Petra Rettberg, Dagmar Koschnitzki, Ralf Moeller, Reinhard Rachel, Reinhard Wirth, Stefan Leuko, Kristina Beblo-Vranesevic, Harald Huber, Bartos Przybyla

Publikováno v: Archives of Microbiology

Radiation of ionizing or non-ionizing nature has harmful effects on cellular components like DNA as radiation can compromise its proper integrity. To cope with damages caused by external stimuli including radiation, within living cells, several fast

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3651cec5ba70283c86bb93b20441bdb4
https://doi.org/10.1007/s00203-020-02125-1

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A promiscuous ancestral enzyme´s structure unveils protein variable regions of the highly diverse metallo-β-lactamase family

Autor: Jennifer Chow, Christoph Heinrich Strunk, Astrid Hoeppner, Holger Gohlke, Filip Kovacic, Wolfgang R. Streit, Harald Huber, Karl-Erich Jaeger, Nicholas Holzscheck, Sander H. J. Smits, Pablo Pérez-García, Stefanie Kobus, Christoph G. W. Gertzen

Publikováno v: Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Communications biology 4(1), 132 (2021). doi:10.1038/s42003-021-01671-8
Communications Biology
'Communications Biology ', vol: 4, pages: 132-1-132-12 (2021)

The metallo-β-lactamase fold is an ancient protein structure present in numerous enzyme families responsible for diverse biological processes. The crystal structure of the hyperthermostable crenarchaeal enzyme Igni18 from Ignicoccus hospitalis was s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3f8255cb565fa072d8c07933fa97e2f
https://doaj.org/article/882f23538291485d9a533860520c28aa

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Akademický článek

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Cytochromes c in Archaea: distribution, maturation, cell architecture and the special case of Ignicoccus hospitalis

Autor: Arnulf eKletzin, Thomas eHeimerl, Jennifer eFlechsler, Laura eVan Niftrik, Reinhard eRachel, Andreas eKlingl

Publikováno v: Frontiers in Microbiology, Vol 6 (2015)

Cytochromes c (Cytc) are widespread electron transfer proteins and important enzymes in the global nitrogen and sulfur cycles. The distribution of Cytc in more than 300 archaeal proteomes deduced from sequence was analyzed with computational methods

Externí odkaz: https://doaj.org/article/b0a260744dae4a48a9a760fd46bd9525

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Identified Hybrid tRNA Structure Genes in Archaeal Genome

Autor: Satyabrata Sahoo, Brajadulal Chattopadhyay, Shib Sankar Das, Uttam Roy Mandal

Publikováno v: Iranian Journal of Biotechnology

Background In Archaea, previous studies have revealed the presence of multiple intron-containing tRNAs and split tRNAs. The full unexpurgated analysis of archaeal tRNA genes remains a challenging task in the field of bioinformatics, because of the pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0094191d2fe3e6cd370b5be39fd5da03
https://doi.org/10.29252/ijb.2254

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Functional compartmentalization and metabolic separation in a prokaryotic cell

Autor: Ivan A. Berg, Harald Huber, Jennifer Flechsler, Thomas Heimerl, Reinhard Rachel

Publikováno v: Proc Natl Acad Sci U S A

The prokaryotic cell is traditionally seen as a ��bag of enzymes,�� yet its organization is much more complex than in this simplified view. By now, various microcompartments encapsulating metabolic enzymes or pathways are known for Bact

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18d034592bb5599f94e73e6bfa94cbf6
https://pubmed.ncbi.nlm.nih.gov/34161262

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Ignicoccus hospitalis – understanding its extraordinary radiation tolerance and an unsolved archaeal repair system

Autor: Palomeque-Dominguez, H.H., Huber, H., Probst, A., Beblo-Vranesevic, K., Rettberg, P.

Ignicoccus hospitalis is an extremophilic Archaea that has demonstrated an extraordinary high tolerance to ionizing radiation. The cells remain viable after exposure to X-ray doses up to 12 kGy, metabolically active after up to 118 kGy and completely

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1640::686c4510989e5c7f82e6d5db97501a3b
https://elib.dlr.de/141941/

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La importancia de Ignicoccus hospitalis en Astrobiología: comprendiendo su extraordinaria tolerancia a la radiación

Autor: Palomeque-Dominguez, H.H., Rettberg, P., Beblo-Vranesevic, K., Probst, A.J.

Ignicoccus hospitalis es un organismo extremófilo que pertenece al dominio Archaea. Se caracteriza por crecer bajo condiciones muy específicas, puesto que es un microbio hipertermófilo, estrictamente anaerobio y quimiolitoautótrofo; metaboliza az

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1640::3a42fea13ab9aa161042bdcb98f82b8a
https://elib.dlr.de/137240/

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