Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Ignazio S Piras"'
Autor:
Glenn S Gerhard, Amanda Hanson, Danielle Wilhelmsen, Ignazio S Piras, Christopher D Still, Xin Chu, Anthony T Petrick, Johanna K DiStefano
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0219764 (2019)
Factors governing the development of liver fibrosis in nonalcoholic steatohepatitis (NASH) are only partially understood. We recently identified adipocyte enhancer binding protein 1 (AEBP1) as a member of a core set of dysregulated fibrosis-specific
Externí odkaz:
https://doaj.org/article/7d9a7df140ee4a8eb0ebdc0803ef121f
Autor:
Cécilia Tremblay, Sidra Aslam, Jessica E. Walker, Ileana Lorenzini, Anthony J. Intorcia, Richard A. Arce, Parichita Choudhury, Charles H. Adler, Holly A. Shill, Erika Driver-Dunckley, Shyamal Mehta, Ignazio S. Piras, Christine M. Belden, Alireza Atri, Thomas G. Beach, Geidy E. Serrano
Publikováno v:
Neurobiology of Disease, Vol 196, Iss , Pp 106514- (2024)
The olfactory bulb is involved early in the pathophysiology of Parkinson's disease (PD), which is consistent with the early onset of olfactory dysfunction. Identifying the molecular mechanisms through which PD affects the olfactory bulb could lead to
Externí odkaz:
https://doaj.org/article/92c40a472abb4d38a754034d735dbb6d
Autor:
Joanna K. Winstone, Khyatiben V. Pathak, Wendy Winslow, Ignazio S. Piras, Jennifer White, Ritin Sharma, Matthew J. Huentelman, Patrick Pirrotte, Ramon Velazquez
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-3 (2024)
Externí odkaz:
https://doaj.org/article/648860bab8b744ce9bb56da9f1fbf418
Autor:
Stefano Mocci, Roberto Littera, Luchino Chessa, Marcello Campagna, Maurizio Melis, Carla Maria Ottelio, Ignazio S. Piras, Sara Lai, Davide Firinu, Stefania Tranquilli, Alessia Mascia, Monica Vacca, Daniele Schirru, Luigi Isaia Lecca, Stefania Rassu, Federica Cannas, Celeste Sanna, Mauro Giovanni Carta, Francesca Sedda, Erika Giuressi, Selene Cipri, Michela Miglianti, Andrea Perra, Sabrina Giglio
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionA large number of risk and protective factors have been identified during the SARS-CoV-2 pandemic which may influence the outcome of COVID-19. Among these, recent studies have explored the role of HLA-G molecules and their immunomodulator
Externí odkaz:
https://doaj.org/article/47e8e78203734accafeb9f800beaf04e
Autor:
Eric Frankel, Avijit Podder, Megan Sharifi, Roshan Pillai, Newell Belnap, Keri Ramsey, Julius Dodson, Pooja Venugopal, Molly Brzezinski, Lorida Llaci, Brittany Gerald, Gabrielle Mills, Meredith Sanchez-Castillo, Chris D. Balak, Szabolcs Szelinger, Wayne M. Jepsen, Ashley L. Siniard, Ryan Richholt, Marcus Naymik, Isabelle Schrauwen, David W. Craig, Ignazio S. Piras, Matthew J. Huentelman, Nicholas J. Schork, Vinodh Narayanan, Sampathkumar Rangasamy
Publikováno v:
Cells, Vol 12, Iss 10, p 1437 (2023)
Mutations of the X-linked gene encoding methyl-CpG-binding protein 2 (MECP2) cause classical forms of Rett syndrome (RTT) in girls. A subset of patients who are recognized to have an overlapping neurological phenotype with RTT but are lacking a mutat
Externí odkaz:
https://doaj.org/article/20acec46706042719162109c33744bd6
Publikováno v:
Cellular Physiology and Biochemistry, Vol 54, Iss 5, Pp 1068-1082 (2020)
Externí odkaz:
https://doaj.org/article/03e489489d08404db67578150fca325a
Autor:
Ignazio S. Piras, Christiane Bleul, Isabelle Schrauwen, Joshua Talboom, Lorida Llaci, Matthew D. De Both, Marcus A. Naymik, Glenda Halliday, Conceicao Bettencourt, Janice L. Holton, Geidy E. Serrano, Lucia I. Sue, Thomas G. Beach, Nadia Stefanova, Matthew J. Huentelman
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-20 (2020)
Abstract Multiple system atrophy (MSA) is a rare adult-onset neurodegenerative disease of unknown cause, with no effective therapeutic options, and no cure. Limited work to date has attempted to characterize the transcriptional changes associated wit
Externí odkaz:
https://doaj.org/article/802f2088948d4fdeaa8617526511b565
Autor:
Candace R. Lewis, Adrienne Henderson-Smith, Reagan S. Breitenstein, Hayley A. Sowards, Ignazio S. Piras, Matthew J. Huentelman, Leah D. Doane, Kathryn Lemery-Chalfant
Publikováno v:
Epigenetics, Vol 14, Iss 3, Pp 310-323 (2019)
Individual differences in cognitive function are due to a combination of heritable and non-heritable factors. A large body of evidence from clinical, cognitive, and pharmacological neuroscience implicates dopaminergic gene variants as modulators of c
Externí odkaz:
https://doaj.org/article/670891c6f1484e30bc4f1bda2f7ac658
Autor:
Malik Nassan, Ignazio S. Piras, Emily Rogalski, Changiz Geula, M. Marsel Mesulam, Matt Huentelman
Publikováno v:
Neurology. 100:e1922-e1929
Background and ObjectivesPrimary progressive aphasia (PPA) is a neurodegenerative syndrome of progressive language decline. PPA has 3 main subtypes: logopenic, semantic, and agrammatic. Observational studies suggested an association between language-
Autor:
Sara Caputo, Matteo Grioni, Chiara S. Brambillasca, Antonella Monno, Arianna Brevi, Massimo Freschi, Ignazio S. Piras, Angela R. Elia, Valentina Pieri, Tania Baccega, Angelo Lombardo, Rossella Galli, Alberto Briganti, Claudio Doglioni, Elena Jachetti, Matteo Bellone
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Galectin-3 (Gal-3) is an extracellular matrix glycan-binding protein with several immunosuppressive and pro-tumor functions. The role of Galectin-3 in cancer stem-like cells (CSCs) is poorly investigated. Here, we show that prostate CSCs also coloniz
Externí odkaz:
https://doaj.org/article/dab02ef43ae54c17978c2f206899e80e