Výsledky vyhledávání - "Ignatius, Tintu"

Crystal structure of phospholipase A

Autor: Kalarickal V, Dileep, Chandran, Remya, Ignatius, Tintu, Pradeep K, Mandal, Ponnuraj, Karthe, Madathilkovilakathu, Haridas, Chittalakkottu, Sadasivan

Publikováno v: IUBMB life. 70(10)

Phospholipase A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1863b84d89095e8895b67f984bfc3045
https://pubmed.ncbi.nlm.nih.gov/30120882

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Interactions of selected indole derivatives with phospholipase A₂: in silico and in vitro analysis

Autor: Kalarickal Vijayan, Dileep, Chandran, Remya, Ignatius, Tintu, Madathilkovilakathu, Haridas, Chittalakkottu, Sadasivan

Publikováno v: Journal of molecular modeling. 19(4)

Phospholipase A2 (PLA₂) is one of the key enzymes involved in the formation of inflammatory mediators. Inhibition of PLA₂ is considered to be one of the efficient methods to control inflammation. In silico docking studies of 160 selected indole d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3581ee6c0a689f04d730459f345046f5
https://pubmed.ncbi.nlm.nih.gov/23315198

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An isoquinoline alkaloid, berberine, can inhibit fungal alpha amylase: enzyme kinetic and molecular modeling studies

Autor: Ignatius, Tintu, Kalarickal V, Dileep, Anu, Augustine, Chittalakkottu, Sadasivan

Publikováno v: Chemical biologydrug design. 80(4)

Aspergillus flavus is a commonly found fungal pathogen, which produces aflatoxins, highly toxic and hepatocarcinogenic natural compounds. Inhibition of fungal alpha amylase activity has been found to limit the ability of the fungus to produce aflatox

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dba802884a072146b21e2ae619402693
https://pubmed.ncbi.nlm.nih.gov/22690956

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Binding to PLA2 may contribute to the anti-inflammatory activity of catechol

Autor: Kalarickal V, Dileep, Ignatius, Tintu, Pradeep K, Mandal, Ponnuraj, Karthe, Madathilkovilakathu, Haridas, Chittalakkottu, Sadasivan

Publikováno v: Chemical biologydrug design. 79(1)

Inhibiting PLA(2) activity should, in theory, be an effective approach to control the inflammation. Several naturally occurring polyphenolic compounds have been reported as inhibitors of PLA(2) . Among the naturally occurring polyphenols, catechol (1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d4d9c6b200d8f5adb2bc2682f5c39569
https://pubmed.ncbi.nlm.nih.gov/21995306

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