Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ignasi Miquel"'
Autor:
Alberto Centeno, Santiago Rojas, Belén Arias, Ignasi Miquel, Pilar Sánchez, Claudia Ureta, Esther Rincón, Ramón López, Jesús Murat
Publikováno v:
Journal of Investigative Surgery, Vol 33, Iss 4, Pp 339-349 (2020)
Background: Excessive blood loss is a relevant complication of partial liver resection. Topical hemostatic agents have proven useful to improve the control of the bleeding in this among other surgical indications. Until now all of these products have
Externí odkaz:
https://doaj.org/article/e53ab0e2b25c413faf41cb6472307d9b
Autor:
Alberto Centeno, Pilar Sánchez, Ignasi Miquel, José Raúl Herance, Esther Rincón, Belén Arias, Javier Valero, Santiago Rojas Codina, Ramón López, Jesús Murat
Publikováno v:
Journal of Burn Care & Research. 38:e824-e833
Blood loss during grafting surgery represents a major concern of this procedure and the development of hemostatic agents for this indication is highly desirable. TT-173 is the first biologically active treatment based on tissue factor instead of thro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71d6d395bba71678021bae2b3ac82baf
https://doi.org/10.1097/bcr.0000000000000497
https://doi.org/10.1097/bcr.0000000000000497
Autor:
Santiago Rojas, Juan Domingo Gispert, José Raúl Herance, Pilar Sánchez, Jesús Murat, Ignasi Miquel, Ramón López, Esther Rincón, Belén Arias
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics. 42:583-592
TT-173 is the first topical hemostatic agent based on tissue factor. To prevent thromboembolic events and intravascular coagulation it is necessary to rule out the systemic absorption of new bioactive hemostats. Here, we radiolabeled TT-173 with [18F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9e6905cec8089500f8c268cff8e9faa
https://doi.org/10.1007/s13318-016-0366-x
https://doi.org/10.1007/s13318-016-0366-x
Autor:
Pilar Sánchez, Esther Rincón, Belén Arias, Alberto Centeno, Ramón López, Jesús Murat, Claudia Ureta, Ignasi Miquel, Santiago Rojas
Publikováno v:
Journal of investigative surgery : the official journal of the Academy of Surgical Research. 33(4)
Background: Excessive blood loss is a relevant complication of partial liver resection. Topical hemostatic agents have proven useful to improve the control of the bleeding in this among other surgi...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec9bc1bc80fa5ffeda350207ab1c0a77
https://pubmed.ncbi.nlm.nih.gov/30380352
https://pubmed.ncbi.nlm.nih.gov/30380352
A new topical hemostatic agent TT-173 reduces blood loss in a sheep model of total knee arthroplasty
Autor:
Ramón López, Santiago Rojas, Ignasi Miquel, Jesús Murat, Alberto Centeno, Esther Rincón, Pilar Sánchez, Belén Arias, Claudia Ureta
Publikováno v:
The Knee. 24(6)
Background Total knee arthroplasty is associated with blood loss during the intervention and may require allogenic blood transfusion. Treatments such as tranexamic acid and fibrin sealants improved the bleeding control in several clinical trials, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84418e182d56803588a06e4d2c5dbac3
https://pubmed.ncbi.nlm.nih.gov/28865948
https://pubmed.ncbi.nlm.nih.gov/28865948
Autor:
Esther Rincón, Santiago Rojas, Belén Arias, Enric Jané-Salas, José López-López, Jesús Murat, Juan R. Rodríguez, Ramón López, Amparo Santamaría, Pilar Sánchez, Beatriz González-Navarro, Ignasi Miquel, Carlos Arranz-Obispo
Publikováno v:
Clinical oral investigations. 20(5)
TT-173 is a new hemostatic agent consisting of yeast-derived microvesicles containing a modified version of recombinant human tissue factor. In the present work, the procoagulant activity of TT-173 has been evaluated for the first time in humans.This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b9f6565d74fe4733e90518a028cc33d
https://pubmed.ncbi.nlm.nih.gov/26374745
https://pubmed.ncbi.nlm.nih.gov/26374745
Autor:
Tomas Roca, Juan-Lorenzo Catena, Joan Bosch, Ignasi Miquel, Oriol Llorens, Ana Fernandez‐Serrat, Juan‐Jesus Perez, A.G. Fernández, Carmen Lagunas, Carles Farrerons
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 10:1745-1748
The synthesis and structure–activity relationships (SAR) of a series of novel selective COX-2 inhibitors are reported. The results show that some of the 1,3,4-triaryl-3-pyrrolin-2-ones 1 are more potent as COX-2 inhibitors than celecoxib, and that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d459ee1b476aef94de369040117f46a2
https://doi.org/10.1016/s0960-894x(00)00329-2
https://doi.org/10.1016/s0960-894x(00)00329-2
Publikováno v:
Scopus-Elsevier
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfd81d78519148c87d1561f85807379f
https://doi.org/10.1055/s-2000-6396
https://doi.org/10.1055/s-2000-6396
Publikováno v:
ChemInform. 31
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccfc40499ae8f86c2e413307a20bef5c
https://doi.org/10.1002/chin.200036119
https://doi.org/10.1002/chin.200036119
Autor:
Carles Farrerons, Ana Fernandez‐Serrat, Joan Bosch, Juan‐Jesus Perez, Juan-Lorenzo Catena, Ignasi Miquel, Oriol Llorens, A.G. Fernández, Carmen Lagunas, Tomas Roca
Publikováno v:
ChemInform. 31
The synthesis and structure–activity relationships (SAR) of a series of novel selective COX-2 inhibitors are reported. The results show that some of the 1,3,4-triaryl-3-pyrrolin-2-ones 1 are more potent as COX-2 inhibitors than celecoxib, and that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66ee4acd2447a48fb127c2600ed74edf
https://doi.org/10.1002/chin.200044128
https://doi.org/10.1002/chin.200044128