Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Ignasi Escamilla"'
Autor:
Ignasi Escamilla, José Alfón, L. A. Gomez, Elena Carceller, Julian Garcia-Rafanell, Carmen Almansa, Robert Soliva, Agusti Miralles, Alberto Fernández de Arriba, Manuel Merlos, F. L. Cavalcanti, Javier Bartroli
Publikováno v:
Journal of Medicinal Chemistry. 46:3463-3475
The synthesis and the pharmacological activity of a series of 1,5-diarylimidazoles developed as potent and selective cyclooxygenase-2 (COX-2) inhibitors are described. The new compounds were evaluated both in vitro (COX-1 and COX-2 inhibition in huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c9ca1d3a6a1e1b4dc9106f92f504d45
https://doi.org/10.1021/jm030765s
https://doi.org/10.1021/jm030765s
Autor:
Javier Forn, Julian Garcia-Rafanell, Manuel Merlos, Rosa Ferrando, Ignasi Escamilla, Joaquin Ramis, Elena Carceller, Marta Giral, Jordi Salas
Publikováno v:
ChemInform. 32
This paper describes the synthesis of a series of azo compounds able to deliver 5-aminosalicylic acid (5-ASA) and a potent platelet activating factor (PAF) antagonist in a colon-specific manner for the purpose of treating ulcerative colitis. We found
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ff81e625aea6af64a0122be55735f67
https://doi.org/10.1002/chin.200150084
https://doi.org/10.1002/chin.200150084
Autor:
Rosa Ferrando, Elena Carceller, Manuel Merlos, Julian Garcia-Rafanell, Ignasi Escamilla, Javier Forn, Joaquin Ramis, Marta Giral, Jordi Salas
Publikováno v:
Journal of medicinal chemistry. 44(18)
This paper describes the synthesis of a series of azo compounds able to deliver 5-aminosalicylic acid (5-ASA) and a potent platelet activating factor (PAF) antagonist in a colon-specific manner for the purpose of treating ulcerative colitis. We found
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8553dd2f3f9f00edf40a6d608935973e
https://pubmed.ncbi.nlm.nih.gov/11520209
https://pubmed.ncbi.nlm.nih.gov/11520209