Innenrücktitelbild: The Essential Role of Water Molecules in the Reaction Mechanism of Protein O‐ Fucosyltransferase 2 (Angew. Chem. 48/2022)

Autor: Ignacio Sanz‐Martínez, Ana García‐García, Tomás Tejero, Ramón Hurtado‐Guerrero, Pedro Merino

Publikováno v: Angewandte Chemie. 134

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e5e20ca230f0cd232ceed5179b2dca35
https://doi.org/10.1002/ange.202216345

The Essential Role of Water Molecules in the Reaction Mechanism of Protein O-Fucosyltransferase 2

Autor: Ignacio Sanz‐Martínez, Ana García‐García, Tomás Tejero, Ramón Hurtado‐Guerrero, Pedro Merino

Publikováno v: Sanz-Martínez, I, García-García, A, Tejero, T, Hurtado-Guerrero, R & Merino, P 2022, ' The Essential Role of Water Molecules in the Reaction Mechanism of Protein O-Fucosyltransferase 2 ', Angewandte Chemie-International Edition, vol. 61, no. 48, e202213610 . https://doi.org/10.1002/anie.202213610

Protein O-fucosyltransferase 2 (PoFUT2) is an inverting glycosyltransferase (GT) that fucosylates thrombospondin repeats (TSRs) from group 1 and 2. PoFUT2 recognizes a large and diverse number of TSRs through a dynamic network of water-mediated inter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d21e5c30a2934b4e6591ea5bef517fdd
https://curis.ku.dk/portal/da/publications/the-essential-role-of-water-molecules-in-the-reaction-mechanism-of-protein-ofucosyltransferase-2(165e4490-eec2-4d51-99ab-012926479a3a).html