Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Ignacio Sanchez‐Burgos"'
Autor:
Samuel Blazquez, Ignacio Sanchez‐Burgos, Jorge Ramirez, Tim Higginbotham, Maria M. Conde, Rosana Collepardo‐Guevara, Andres R. Tejedor, Jorge R. Espinosa
Publikováno v:
Advanced Science, Vol 10, Iss 25, Pp n/a-n/a (2023)
Abstract Maturation of functional liquid‐like biomolecular condensates into solid‐like aggregates has been linked to the onset of several neurodegenerative disorders. Low‐complexity aromatic‐rich kinked segments (LARKS) contained in numerous
Externí odkaz:
https://doaj.org/article/57e039561584474296f51f4b1026f5f3
Autor:
Andres R. Tejedor, Ignacio Sanchez-Burgos, Maria Estevez-Espinosa, Adiran Garaizar, Rosana Collepardo-Guevara, Jorge Ramirez, Jorge R. Espinosa
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
In this work the authors propose a multiscale computational approach, integrating atomistic and coarse-grained models simulations, to study the thermodynamic and kinetic factors playing a major role in the liquid-to-solid transition of biomolecular c
Externí odkaz:
https://doaj.org/article/170bb750ecf24d71ab9d21986a7d0cc6
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Biomolecular condensates are liquid-like membraneless compartments that contribute to the spatiotemporal organization of proteins, RNA, and other biomolecules inside cells. Some membraneless compartments, such as nucleoli, are dispersed as d
Externí odkaz:
https://doaj.org/article/521a2f5926d8490f959614a9ad5e2782
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 2, p e1009810 (2022)
Biomolecular condensates formed via liquid-liquid phase separation (LLPS) play a crucial role in the spatiotemporal organization of the cell material. Nucleic acids can act as critical modulators in the stability of these protein condensates. To unve
Externí odkaz:
https://doaj.org/article/48bd1ca6b16048ff94fece7e4cdabdff
Publikováno v:
Biomolecules, Vol 11, Iss 2, p 278 (2021)
Biomolecular condensates, which assemble via the process of liquid–liquid phase separation (LLPS), are multicomponent compartments found ubiquitously inside cells. Experiments and simulations have shown that biomolecular condensates with many compo
Externí odkaz:
https://doaj.org/article/55325487bd2645b4a66d1149ec393724
Publikováno v:
Molecules, Vol 25, Iss 20, p 4705 (2020)
Proteins containing intrinsically disordered regions (IDRs) are ubiquitous within biomolecular condensates, which are liquid-like compartments within cells formed through liquid–liquid phase separation (LLPS). The sequence of amino acids of a prote
Externí odkaz:
https://doaj.org/article/4850ee069581403b944154ebe39a9287
Publikováno v:
Physical Review Letters. 130
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ece584e10dc2008e59c9aaffa9516362
https://doi.org/10.1103/physrevlett.130.118001
https://doi.org/10.1103/physrevlett.130.118001
Autor:
Adiran Garaizar, Tim Higginbotham, Ignacio Sanchez-Burgos, Andres R. Tejedor, Eduardo Sanz, Jorge R. Espinosa
Colloidal systems possess unique features to investigate the governing principles behind liquid-to-solid transitions. The phase diagram and crystallization landscape of colloidal particles can be finely tuned by the range, number and angular distribu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba34ef8f1b76a7eeb15b6fde9112dcf8
Autor:
Ignacio Sanchez-Burgos, Maria Carolina Muniz, Jorge R. Espinosa, Athanassios Z. Panagiotopoulos
Computational studies of liquid water and its phase transition into vapor have traditionally been performed using classical water models. Here, we utilize the Deep Potential methodology—a machine learning approach—to study this ubiquitous phase t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55d2fc382d77bdfdc199af55f4942eb6
Autor:
Samuel Blazquez, Ignacio Sanchez-Burgos, Jorge Ramirez, Tim Higginbotham, Maria M. Conde, Rosana Collepardo-Guevara, Andres R. Tejedor, Jorge R. Espinosa
Maturation of functional liquid-like biomolecular condensates into solid-like aggregates has been linked to the onset of several neurodegenerative disorders. Low-complexity aromatic-rich kinked segments (LARKS) contained in numerous RNA-binding prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60b5718000a6352e351aaf08cbe61909
https://doi.org/10.1101/2022.12.14.520383
https://doi.org/10.1101/2022.12.14.520383