Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ignacio Rodriguez-Izquierdo"'
Publikováno v:
Molecules, Vol 25, Iss 13, p 2965 (2020)
Anionic carbosilane dendrimers such as G2-S16 are very effective in preventing HSV-2 infection both in vitro and in vivo. We present the main achievements obtained for the G2-S16 dendrimer in vivo, especially related to its efficacy against HSV-2 inf
Externí odkaz:
https://doaj.org/article/0befc75a4b4c492db4efe3dd9597f40f
Autor:
Carlos Guerrero-Beltrán, Inmaculada Garcia-Heredia, Rafael Ceña-Diez, Ignacio Rodriguez-Izquierdo, María Jesús Serramía, Francisco Martinez-Hernandez, Mónica Lluesma-Gomez, Manuel Martinez-Garcia, María Ángeles Muñoz-Fernández
Publikováno v:
Pharmaceutics, Vol 12, Iss 6, p 515 (2020)
The G2-S16 polyanionic carbosilane dendrimer is a promising microbicide that inhibits HSV-2 infection in vitro and in vivo in mice models. This G2-S16 dendrimer inhibits HSV-2 infection even in the presence of semen. Murine models, such as BALB/c fem
Externí odkaz:
https://doaj.org/article/a00a1c121322481fb1da42f136415bb1
Publikováno v:
Nanomedicine. 14:1095-1107
Aim: Polyanionic carbosilane dendrimers have been shown to be safe and block human immunodeficiency virus type 1 (HIV-1) infection in a multifunctional manner. The aim of this study is to evaluate the appearance of HIV-1 resistance mutations after tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3dd656c20a1d1fb09ed19c94802bcd4
https://doi.org/10.2217/nnm-2018-0364
https://doi.org/10.2217/nnm-2018-0364
Autor:
Rosa Rodriguez-Fernández, María Jesús Serramía, Ignacio Rodriguez-Izquierdo, Mariángeles Muñoz-Fernández, Rafael Ceña-Diez, Isidoro Martínez
Publikováno v:
Polymers, Vol 13, Iss 2141, p 2141 (2021)
Repisalud
Instituto de Salud Carlos III (ISCIII)
Polymers
Volume 13
Issue 13
Repisalud
Instituto de Salud Carlos III (ISCIII)
Polymers
Volume 13
Issue 13
The respiratory syncytial virus (RSV) causes respiratory infection and bronchiolitis, requiring hospitalization mainly in infants. The interaction between RSV, envelope glycoproteins G and F, and cell surface heparan sulfate proteoglycans (HSPG) is r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c2ac015cf869b9addf02cdb1678b552
https://hdl.handle.net/20.500.12105/13981
https://hdl.handle.net/20.500.12105/13981
Autor:
Ignacio Rodriguez-Izquierdo, E. Royo-Rubio, M. A. Muñoz-Fernández, Tania Lozano-Cruz, M. Moreno-Domene, F. J. de la Mata, Rafael Gómez, Jose L. Jimenez
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-16 (2021)
Journal of Nanobiotechnology
Journal of Nanobiotechnology
Background The appearance of resistance against new treatments and the fact that HIV-1 can infect various cell types and develop reservoirs and sanctuaries makes it necessary to develop new therapeutic approaches to overcome those failures. Results S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eaac032b2195552c2b5aaec9f84e18d
https://doi.org/10.1186/s12951-021-00899-0
https://doi.org/10.1186/s12951-021-00899-0
Autor:
Daniel Sepúlveda-Crespo, Ignacio Rodriguez-Izquierdo, Anna M. Costa, Jaume Vilarrasa, M. Ángeles Muñoz-Fernández, Elena Petit, Lluís Bosch
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Universidad de Barcelona
Amides from indole-3-glyoxylic acid and 4 - benzoyl-2-methyl-piperazine, which are related to entry inhibitors developed by Bristol-Myers Squibb (BMS), have been synthesized with aliphatic chains located at the C7 position of the indole ring. These s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cba6073589fe51dedfb465c711934c3
http://hdl.handle.net/2445/186028
http://hdl.handle.net/2445/186028
Autor:
Jorge Rubén Cabrera, Ignacio Rodriguez-Izquierdo, Jose L. Jimenez, María Ángeles Muñoz-Fernández
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-15 (2020)
Journal of Neuroinflammation
Journal of Neuroinflammation
BackgroundGenetics have provided hints on potential molecular pathways involved in neurodegenerative diseases (NDD). However, the number of cases caused exclusively by genetic alterations is low, suggesting an important contribution of environmental
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7ae80523bf8bea33dc424ba9cde64e6
https://doi.org/10.1186/s12974-020-02044-4
https://doi.org/10.1186/s12974-020-02044-4
Autor:
Ignacio Rodriguez-Izquierdo, María Jesús Serramía, Francisco Martinez-Hernandez, Carlos Enrique Guerrero-Beltrán, Manuel Martinez-Garcia, Mónica Lluesma-Gomez, Inmaculada Garcia-Heredia, María Ángeles Muñoz-Fernández, Rafael Ceña-Diez
Publikováno v:
Pharmaceutics
Volume 12
Issue 6
Pharmaceutics, Vol 12, Iss 515, p 515 (2020)
Volume 12
Issue 6
Pharmaceutics, Vol 12, Iss 515, p 515 (2020)
The G2-S16 polyanionic carbosilane dendrimer is a promising microbicide that inhibits HSV-2 infection in vitro and in vivo in mice models. This G2-S16 dendrimer inhibits HSV-2 infection even in the presence of semen. Murine models, such as BALB/c fem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::788a07a0cc0bb361bb6e508956377b2b
https://pubmed.ncbi.nlm.nih.gov/32512836
https://pubmed.ncbi.nlm.nih.gov/32512836
Autor:
Francisco Javier de la Mata, Ma Jesús Serramía, Ingrid Araya-Durán, Rafael Gómez, Valeria Márquez-Miranda, Fernando D. González-Nilo, M. Ángeles Muñoz-Fernández, Carlos Guerrero-Beltrán, Ignacio Rodriguez-Izquierdo, Manuel Leal
Publikováno v:
Bioconjugate Chemistry. 29:1584-1594
Cell-to-cell transmission is the most effective pathway for the spread of human immunodeficiency virus (HIV-1). Infected cells expose virus-encoded fusion proteins on their surface as a consequence of HIV-1 replicative cycle that interacts with nonin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16ffc0fb218163e8bcfb525b10e39b38
https://doi.org/10.1021/acs.bioconjchem.8b00106
https://doi.org/10.1021/acs.bioconjchem.8b00106
Publikováno v:
Molecules
Molecules, Vol 25, Iss 2965, p 2965 (2020)
Molecules, Vol 25, Iss 2965, p 2965 (2020)
Anionic carbosilane dendrimers such as G2-S16 are very effective in preventing HSV-2 infection both in vitro and in vivo. We present the main achievements obtained for the G2-S16 dendrimer in vivo, especially related to its efficacy against HSV-2 inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7512fcd17f50fd234fc99ba83ee66dbd
https://doi.org/10.3390/molecules25132965
https://doi.org/10.3390/molecules25132965