Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Ignacio Rodríguez-Crespo"'
The CB1 receptor interacts with cereblon and drives cereblon deficiency-associated memory shortfalls
Autor:
Carlos Costas-Insua, Alba Hermoso-López, Estefanía Moreno, Carlos Montero-Fernández, Alicia Álvaro-Blázquez, Irene B Maroto, Andrea Sánchez-Ruiz, Rebeca Diez-Alarcia, Cristina Blázquez, Paula Morales, Enric I Canela, Vicent Casadó, Leyre Urigüen, Gertrudis Perea, Luigi Bellocchio, Ignacio Rodríguez-Crespo, Manuel Guzmán
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 4, Pp 755-783 (2024)
Abstract Cereblon/CRBN is a substrate-recognition component of the Cullin4A-DDB1-Roc1 E3 ubiquitin ligase complex. Destabilizing mutations in the human CRBN gene cause a form of autosomal recessive non-syndromic intellectual disability (ARNSID) that
Externí odkaz:
https://doaj.org/article/5c7b69f9446144719e20ce1f4a631547
Autor:
Mónica Gómez-Parrizas, Teresa Iglesias, Clara Aicart-Ramos, Carlos Zaragoza, Lucía Sánchez-Ruiloba, Ignacio Rodríguez-Crespo
Publikováno v:
Journal of Cell Science.
This Expression of Concern relates to the article ‘Protein kinase D activity controls endothelial nitric oxide synthesis’ by Clara Aicart-Ramos, Lucia Sanchez-Ruiloba, Monica Gomez-Parrizas, Carlos Zaragoza, Teresa Iglesias and Ignacio Rodriguez-
Autor:
Alberto Álvarez Barrientos, Lisardo Boscá, Ignacio Rodríguez-Crespo, Inmaculada Navarro-Lérida, Francisco Gavilanes, María Teresa Portolés
Publikováno v:
Journal of Cell Science.
This Expression of Concern relates to the article ‘Induction of nitric oxide synthase-2 proceeds with the concomitant downregulation of the endogenous caveolin levels’ by Inmaculada Navarro-Lerida, Maria Teresa Portoles, Alberto Alvarez Barriento
Publikováno v:
Journal of Cell Science.
This Expression of Concern relates to the article ‘N-terminal palmitoylation within the appropriate amino acid environment conveys on NOS2 the ability to progress along the intracellular sorting pathways’ by Inmaculada Navarro-Lerida, Alberto Alv
Autor:
Francisco Gavilanes, Alberto Álvarez-Barrientos, Ignacio Rodríguez-Crespo, Inmaculada Navarro-Lérida
Publikováno v:
Journal of Cell Science.
This Expression of Concern relates to the article ‘Distance-dependent cellular palmitoylation of de-novo-designed sequences and their translocation to plasma membrane subdomains’ by Inmaculada Navarro-Lerida, Alberto Alvarez-Barrientos, Francisco
Autor:
Irene B. Maroto, Carlos Costas-Insua, Coralie Berthoux, Estefanía Moreno, Andrea Ruiz-Calvo, Carlos Montero-Fernández, Andrea Macías-Camero, Ricardo Martín, Nuria García-Font, José Sánchez-Prieto, Giovanni Marsicano, Luigi Bellocchio, Enric I. Canela, Vicent Casadó, Ismael Galve-Roperh, Ángel Núñez, David Fernández de Sevilla, Ignacio Rodríguez-Crespo, Pablo E. Castillo, Manuel Guzmán
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract The type-1 cannabinoid receptor (CB1R) is widely expressed in excitatory and inhibitory nerve terminals, and by suppressing neurotransmitter release, its activation modulates neural circuits and brain function. While the interaction of CB1R
Externí odkaz:
https://doaj.org/article/de2f897065d34da0933b217db4f53983
Autor:
Alba Hermoso-López, Carlos Costas-Insua, Carlos Montero-Fernández, Estefanía Moreno, Alicia Álvaro-Blázquez, David Martín-Gutiérrez, Irene B. Maroto-Martínez, Rebeca Diez-Alarcia, Leyre Urigüen, Vicent Casadó, Ignacio Rodríguez-Crespo, Manuel Guzmán
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S848- (2023)
Externí odkaz:
https://doaj.org/article/b668f7103ab240249d28d67435c8975d
Autor:
Marta Gómez-Almería, Sonia Burgaz, Carlos Costas-Insua, Carmen Rodríguez-Cueto, Irene Santos-García, Ignacio Rodríguez-Crespo, Concepción García, Manuel Guzmán, Eva de Lago, Javier Fernández-Ruiz
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 22, p 12533 (2021)
In the present study, we investigated the involvement of the chaperone protein BiP (also known as GRP78 or Hspa5), a master regulator of intracellular proteostasis, in two mouse models of neurodegenerative diseases: amyotrophic lateral sclerosis (ALS
Externí odkaz:
https://doaj.org/article/0596c9acd46f48c0a93625dc3145c5b7
Autor:
Irene Maroto, Carlos Costas-Insua, Coralie Berthoux, Estefania Moreno, Andrea Ruiz-Calvo, Carlos Montero-Fernández, Andrea Macías-Camero, Ricardo Martín, Nuria García-Font, José Sánchez-Prieto, Giovanni Marsicano, Luigi Bellocchio, Enric Canela, Vicent Casado, Ismael Galve-Roperh, David Fernandez de Sevilla, Ignacio Rodríguez-Crespo, Pablo Castillo, Manuel Guzmán
The type-1 cannabinoid receptor (CB1R) is widely expressed in both excitatory and inhibitory nerve terminals, and its activation, by suppressing neurotransmitter release, modulates neural circuits and brain function. While the interaction of CB1R wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbe7ee7b82e20f34c072bc9d419c1894
https://doi.org/10.21203/rs.3.rs-2128033/v1
https://doi.org/10.21203/rs.3.rs-2128033/v1
Autor:
Eva de Lago, Carlos Costas-Insua, Concepción García, Javier Fernández-Ruiz, Irene Santos-García, Marta Gómez-Almería, Carmen Rodríguez-Cueto, Ignacio Rodríguez-Crespo, Sonia Burgaz, Manuel Guzmán
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 12533, p 12533 (2021)
E-Prints Complutense. Archivo Institucional de la UCM
instname
Volume 22
Issue 22
International Journal of Molecular Sciences, Vol 22, Iss 12533, p 12533 (2021)
E-Prints Complutense. Archivo Institucional de la UCM
instname
Volume 22
Issue 22
In the present study, we investigated the involvement of the chaperone protein BiP (also known as GRP78 or Hspa5), a master regulator of intracellular proteostasis, in two mouse models of neurodegenerative diseases: amyotrophic lateral sclerosis (ALS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4bc1bfd855af5e80951c7965f9221ce
https://eprints.ucm.es/id/eprint/71672/
https://eprints.ucm.es/id/eprint/71672/