Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Ignacio Portales-Castillo"'
Autor:
Ignacio Portales‐Castillo, Rhea Singal, Anastasia Ambrose, Jong Hee Song, Minsoo Son, Young Ah. Goo, Wen Zhou, Avram Z. Traum, Ariella Coler‐Reilly, Benjamin D. Humphreys, Roberto Civitelli, Harald Jüppner, Andrew L. Lundquist, Peter Seres, Andrew S. Allegretti, Saadet Mercimek‐Andrews
Publikováno v:
JIMD Reports, Vol 65, Iss 5, Pp 341-353 (2024)
Abstract Autosomal dominant Fanconi syndrome due to a GATM variant (GATM‐FS), causes accumulation of misfolded arginine‐glycine amidinotransferase (AGAT) in proximal renal tubules leading to cellular injury. GATM‐FS presents during childhood an
Externí odkaz:
https://doaj.org/article/ed57ef7a83974f628ba4c03ecfbbcf4e
Autor:
Ignacio Portales-Castillo, Thomas Dean, Ross W. Cheloha, Brendan A. Creemer, Jean-Pierre Vilardaga, Sofya Savransky, Ashok Khatri, Harald Jüppner, Thomas J. Gardella
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-16 (2023)
Abstract The parathyroid hormone receptor type 1 (PTH1R) is a G protein-coupled receptor that plays key roles in regulating calcium homeostasis and skeletal development via binding the ligands, PTH and PTH-related protein (PTHrP), respectively. Eiken
Externí odkaz:
https://doaj.org/article/d0a31e57caaa4dbf92dd88b401fee037
Autor:
Ignacio Portales-Castillo, Petra Simic
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
The actions of several bone-mineral ion regulators, namely PTH, FGF23, Klotho and 1,25(OH)2 vitamin D (1,25(OH)2D), control calcium and phosphate metabolism, and each of these molecules has additional biological effects related to cell signaling, met
Externí odkaz:
https://doaj.org/article/93f9af770daa40568a2fc91189600dca
Publikováno v:
JBMR Plus, Vol 6, Iss 6, Pp n/a-n/a (2022)
ABSTRACT Consistent with a vital role of parathyroid hormone (PTH) receptor type 1 (PTH1R) in skeletal development, homozygous loss‐of‐function PTH1R mutations in humans results in neonatal lethality (Blomstrand chondrodysplasia), whereas such he
Externí odkaz:
https://doaj.org/article/eb9bcb100ccb4bca867528b864b0ef67
Autor:
Ignacio Portales-Castillo, David B. Mount, Sagar U. Nigwekar, Elaine W. Yu, Helmut G. Rennke, Shruti Gupta
Publikováno v:
American Journal of Kidney Diseases. 80:555-559
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21e1e30092780d19f968ae0984ade4ab
https://doi.org/10.1053/j.ajkd.2021.12.015
https://doi.org/10.1053/j.ajkd.2021.12.015
Autor:
Cagri Aksu, Ian A. Strohbehn, Sagar U. Nigwekar, Sophia Zhao, Meghan E. Sise, Ignacio Portales-Castillo, Elaine W. Yu
Publikováno v:
Kidney Medicine, Vol 3, Iss 6, Pp 1112-1115 (2021)
Kidney Medicine
Kidney Medicine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::466312d373e19dd3ae2e3a31f266b176
http://www.sciencedirect.com/science/article/pii/S2590059521002016
http://www.sciencedirect.com/science/article/pii/S2590059521002016
Autor:
Wen Wen, Ignacio Portales-Castillo, Rituvanthikaa Seethapathy, Scott Krinsky, Daniela Kroshinsky, Sahir Kalim, Jeremy Goverman, Rosalynn M Nazarian, Vipul Chitalia, Rajeev Malhotra, Rafael Kramann, Cindy K Malhotra, Sagar U Nigwekar
Publikováno v:
Nephrol Dial Transplant
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association-European Renal Association, 38(3), 733-745. Oxford University Press
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association-European Renal Association, 38(3), 733-745. Oxford University Press
Background Vascular calcification (VC) is a common comorbidity among patients with chronic kidney disease (CKD), indicating major cardiovascular events. This study aimed to evaluate the effects and safety of intravenous sodium thiosulphate (STS) for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62caf46b31bdd3774474f7252fc25bd8
https://europepmc.org/articles/PMC10111152/
https://europepmc.org/articles/PMC10111152/
Autor:
Sagar Nigwekar, Shelsea St Hillien, Rituvanthikaa Seethapathy, Scott Krinsky, Jeanfranco Torcatti, Jennifer Howe, Sahir Kalim, Ignacio Portales-Castillo, Beza Mengesha, Wen Wen, Borut Cizman, Yves Sabbagh
Publikováno v:
Nephrology Dialysis Transplantation. 37
BACKGROUND AND AIMS Calciphylaxis is a rare but devastating disorder predominantly affecting patients with end-stage kidney disease [1]. Patients with calciphylaxis present with painful ischemic skin lesions caused by microvascular occlusion secondar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe4e493a2423af0bb94c4559a06a04e6
https://doi.org/10.1093/ndt/gfac079.030
https://doi.org/10.1093/ndt/gfac079.030
Autor:
Richard H. Sterns, Mamta Chhabria, Jonathan Bress, Atif Sohail, Medhat Chowdhury, Denise Sanchez-Tejera, Ignacio Portales-Castillo
Publikováno v:
American Journal of Kidney Diseases. 76:A9-A12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64781070f9c71041492a07df05c84ea4
https://doi.org/10.1053/j.ajkd.2019.12.020
https://doi.org/10.1053/j.ajkd.2019.12.020