Výsledky vyhledávání - "Ignacio Pérez de Castro"

Akademický článek

Aurora A drives early signalling and vesicle dynamics during T-cell activation

Autor: Noelia Blas-Rus, Eugenio Bustos-Morán, Ignacio Pérez de Castro, Guillermo de Cárcer, Aldo Borroto, Emilio Camafeita, Inmaculada Jorge, Jesús Vázquez, Balbino Alarcón, Marcos Malumbres, Noa B. Martín-Cófreces, Francisco Sánchez-Madrid

Publikováno v: Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)

Aurora A is a protein kinase that contributes to the progression of mitosis by stimulating microtubule nucleation. Here the authors show that Aurora A also functions during T cell activation by maintaining TCR signaling through Lck activation.

Externí odkaz: https://doaj.org/article/70cde4b8e22c4dcfa69bb2d3c104caa9

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Akademický článek

Consequences of Lmna Exon 4 Mutations in Myoblast Function

Autor: Déborah Gómez-Domínguez, Carolina Epifano, Fernando de Miguel, Albert García Castaño, Borja Vilaplana-Martí, Alberto Martín, Sandra Amarilla-Quintana, Anne T Bertrand, Gisèle Bonne, Javier Ramón-Azcón, Miguel A Rodríguez-Milla, Ignacio Pérez de Castro

Publikováno v: Cells, Vol 9, Iss 5, p 1286 (2020)

Laminopathies are causally associated with mutations on the Lamin A/C gene (LMNA). To date, more than 400 mutations in LMNA have been reported in patients. These mutations are widely distributed throughout the entire gene and are associated with a wi

Externí odkaz: https://doaj.org/article/379d7eb624e4498ca25aa0190b1f103c

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