Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Ignacio Pérez‐Victoria"'
Autor:
Maria C. Ramos, Gloria Crespo-Sueiro, Nuria de Pedro, Carmen Griñán-Lisón, Caridad Díaz, Ignacio Pérez-Victoria, Víctor González-Menéndez, Francisco Castillo, Jose Pérez del Palacio, Jose R. Tormo, Duane Choquesillo-Lazarte, Juan A. Marchal, Francisca Vicente, Rosario Fernández-Godino, Olga Genilloud, Fernando Reyes
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 177, Iss , Pp 117018- (2024)
Pancreatic cancer (PC) shows a high fatality rate that can only be faced with a combination of surgery and chemotherapy or palliative treatment in the case of advanced patients. Besides, PC tumors are enriched with subpopulations of cancer stem cells
Externí odkaz:
https://doaj.org/article/8268bf1b9daa42d28c8736e78a8f2af3
Autor:
Mariana Girão, José Murillo-Alba, Jesús Martín, Ignacio Pérez-Victoria, Ricardo B. Leite, Ralph Urbatzka, Pedro N. Leão, Maria F. Carvalho, Fernando Reyes
Publikováno v:
Marine Drugs, Vol 22, Iss 6, p 268 (2024)
Bioprospecting the secondary metabolism of underexplored Actinomycetota taxa is a prolific route to uncover novel chemistry. In this work, we report the isolation, structure elucidation, and bioactivity screening of cellulamides A and B (1 and 2), tw
Externí odkaz:
https://doaj.org/article/6e536551b7b24d8e8621b42876428303
Autor:
Coral García-Gutiérrez, Ignacio Pérez-Victoria, Ignacio Montero, Jorge Fernández-De la Hoz, Mónica G. Malmierca, Jesús Martín, José A. Salas, Carlos Olano, Fernando Reyes, Carmen Méndez
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 4, p 2347 (2024)
Piperazic acid is a cyclic nonproteinogenic amino acid that contains a hydrazine N-N bond formed by a piperazate synthase (KtzT-like). This amino acid, found in bioactive natural products synthesized by non-ribosomal peptide synthetases (NRPSs), conf
Externí odkaz:
https://doaj.org/article/32673565fc0f46c9b746d0c77d31aaf7
Autor:
Suhui Ye, Giovanni Ballin, Ignacio Pérez‐Victoria, Alfredo F. Braña, Jesús Martín, Fernando Reyes, José A. Salas, Carmen Méndez
Publikováno v:
Microbial Biotechnology, Vol 15, Iss 12, Pp 2905-2916 (2022)
Abstract Coelimycin P1 and argimycins P are two types of polyketide alkaloids produced by Streptomyces coelicolor and Streptomyces argillaceus, respectively. Their biosynthesis pathways share some early steps that render very similar aminated polyket
Externí odkaz:
https://doaj.org/article/0462977fc0a8404686a8871d95ce53c2
Autor:
Frederick Annang, Guiomar Pérez-Moreno, Caridad Díaz, Victor González-Menéndez, Nuria de Pedro Montejo, José Pérez del Palacio, Paula Sánchez, Scott Tanghe, Ana Rodriguez, Ignacio Pérez-Victoria, Juan Cantizani, Luis M. Ruiz-Pérez, Olga Genilloud, Fernando Reyes, Francisca Vicente, Dolores González-Pacanowska
Publikováno v:
Malaria Journal, Vol 20, Iss 1, Pp 1-10 (2021)
Abstract Background Malaria is a global health problem for which novel therapeutic compounds are needed. To this end, a recently published novel family of antiplasmodial macrolides, strasseriolides A–D, was herein subjected to in vivo efficacy stud
Externí odkaz:
https://doaj.org/article/19452ec86bc944d3bca7f97ac48433c7
Autor:
Suhui Ye, Brian Molloy, Ignacio Pérez-Victoria, Ignacio Montero, Alfredo F. Braña, Carlos Olano, Sonia Arca, Jesús Martín, Fernando Reyes, José A. Salas, Carmen Méndez
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 9, p 8197 (2023)
Genome mining using standard bioinformatics tools has allowed for the uncovering of hidden biosynthesis gene clusters for specialized metabolites in Streptomyces genomes. In this work, we have used an alternative approach consisting in seeking “Str
Externí odkaz:
https://doaj.org/article/0bf7bf73563d4615bf03b0e677fa3456
Autor:
Ramón I. Santamaría, Ana Martínez-Carrasco, Jesús Martín, José R. Tormo, Ignacio Pérez-Victoria, Ignacio González, Olga Genilloud, Fernando Reyes, Margarita Díaz
Publikováno v:
Antibiotics, Vol 11, Iss 5, p 672 (2022)
Streptomyces bacteria produce a wide number of antibiotics and antitumor compounds that have attracted the attention of pharmaceutical and biotech companies. In this study, we provide evidence showing that the xylem sap from grapevines has a positive
Externí odkaz:
https://doaj.org/article/b0a334f5adab44189a2998ffc23879ec
Autor:
Matilde Ortiz-Gonzalez, Ignacio Pérez-Victoria, Inmaculada Ramirez-Macias, Nuria de Pedro, Angel Linde-Rodriguez, Víctor González-Menéndez, Victoria Sanchez-Martin, Jesús Martín, Ana Soriano-Lerma, Olga Genilloud, Virginia Perez-Carrasco, Francisca Vicente, José Maceira, Carlos A. Rodrígues-Poveda, José María Navarro-Marí, Fernando Reyes, Miguel Soriano, Jose A. Garcia-Salcedo
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 11, p 6107 (2022)
Sleeping sickness or African trypanosomiasis is a serious health concern with an added socio-economic impact in sub-Saharan Africa due to direct infection in both humans and their domestic livestock. There is no vaccine available against African tryp
Externí odkaz:
https://doaj.org/article/0c8cd280fa444817a36da2f071fb9ecc
Autor:
Gloria Crespo, Ignacio Pérez-Victoria, Francisco Javier Ortiz-López, Víctor González-Menéndez, Mercedes de la Cruz, Bastien Cautain, Pilar Sánchez, Francisca Vicente, Olga Genilloud, Fernando Reyes
Publikováno v:
Antibiotics, Vol 9, Iss 6, p 278 (2020)
An antifungal lipodepsipeptide was obtained from cultures of the fungus Foliophoma fallens CF-236885. Its structure, elucidated by HRMS and NMR spectroscopy, contained Gly, Thr, Asn, β-Ala, Orn, Ala, two Ser residues, and 3-hydroxy-4-methylhexadecan
Externí odkaz:
https://doaj.org/article/e08d3aec24ec42afb23378e9b6005d4e
Autor:
Mónica G. Malmierca, Lorena González-Montes, Ignacio Pérez-Victoria, Carlos Sialer, Alfredo F. Braña, Raúl García Salcedo, Jesús Martín, Fernando Reyes, Carmen Méndez, Carlos Olano, José A. Salas
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Many bioactive natural products are glycosylated compounds in which the sugar components usually participate in interaction and molecular recognition of the cellular target. Therefore, the presence of sugar moieties is important, in some cases essent
Externí odkaz:
https://doaj.org/article/d5ffdf28b0c34b71b91c306cee24c81b