Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Ignacio Gonzalez-Suarez"'
Autor:
Diego Marescotti, Carole Mathis, Vincenzo Belcastro, Patrice Leroy, Stefano Acali, Florian Martin, Rémi Dulize, David Bornand, Dariusz Peric, Emmanuel Guedj, Laura Ortega Torres, Matteo Biasioli, Matthieu Fuhrimann, Estela Fernandes, Felix Frauendorfer, Ignacio Gonzalez Suarez, Davide Sciuscio, Nikolai V. Ivanov, Manuel C. Peitsch, Julia Hoeng
Publikováno v:
Toxicology Reports, Vol 7, Iss , Pp 67-80 (2020)
The development of reduced-risk products aims to provide alternatives to cigarettes that present less risk of harm for adult smokers. Responsible use of flavoring substances in these products may fulfill an important role in product acceptance. While
Externí odkaz:
https://doaj.org/article/68c51b0570854c5e873f9c4ebe2b2a39
Autor:
Ignacio Gonzalez Suarez, Remi Dulize, Dariusz Peric, Patrice Leroy, Felix Frauendorfer, Matteo Biasioli, Stefano Acali, Manuel C. Peitsch, Julia Hoeng, Diego Marescotti, Emmanuel Guedj, Davide Sciuscio, Nikolai V. Ivanov, Florian Martin, Estela Fernandes, Matthieu Fuhrimann, Vincenzo Belcastro, David Bornand, Carole Mathis, Laura Ortega Torres
Publikováno v:
Toxicology Reports, Vol 7, Iss, Pp 67-80 (2020)
Toxicology Reports
Toxicology Reports
Graphical abstract
Highlights • A 3-step approach combining 1) real-time cytotoxicity, 2) high-content screening and 3) gene expression analysis was developed in NHBE cells. • Different scoring methods were developed enabling a ranking based
Highlights • A 3-step approach combining 1) real-time cytotoxicity, 2) high-content screening and 3) gene expression analysis was developed in NHBE cells. • Different scoring methods were developed enabling a ranking based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7345c2900d7d86b551b3cb2a12506cd8
http://www.sciencedirect.com/science/article/pii/S2214750019304548
http://www.sciencedirect.com/science/article/pii/S2214750019304548
Autor:
Manuel C. Peitsch, Vincenzo Belcastro, Filipe Bonjour, Julia Hoeng, Stephane Cano, Stefano Acali, Nikolai V. Ivanov, Florian Martin, Ignacio Gonzalez-Suarez, Diego Marescotti, Carine Poussin
Publikováno v:
Bioinformatics
Summary GladiaTOX R package is an open-source, flexible solution to high-content screening data processing and reporting in biomedical research. GladiaTOX takes advantage of the ‘tcpl’ core functionalities and provides a number of extensions: it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99ed679910a669a0e991e8f002eb6064
http://europepmc.org/articles/PMC6792086
http://europepmc.org/articles/PMC6792086
Autor:
Julia Hoeng, Anita R. Iskandar, Diego Marescotti, Jean-Pierre Schaller, Yang Xiang, Nikolai V. Ivanov, Florian Martin, Emmanuel Guedj, Alain Sewer, Ignacio Gonzalez-Suarez, Patrick Vanscheeuwijck, Shoaib Majeed, Stefan Frentzel, Patrice Leroy, Manuel C. Peitsch, Carole Mathis
Publikováno v:
Toxicology Mechanisms and Methods
Various electronic nicotine delivery systems (ENDS), of which electronic cigarettes (e-cigs) are the most recognized prototype, have been quickly gaining ground on conventional cigarettes because they are perceived as less harmful. Research assessing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0d6daa1b68b56a292140dfb52f3584f
https://doi.org/10.3109/15376516.2016.1170251
https://doi.org/10.3109/15376516.2016.1170251
Autor:
Dariusz Peric, Claudius Pak, Stefano Acali, David Bornand, Julia Hoeng, Emmanuel Guedj, Athanasios Kondylis, Nikolai V. Ivanov, Elodie Maluenda, Didier Goedertier, Alexandra Laurent, Ignacio Gonzalez Suarez, Karine Baumer, Remi Dulize, Diego Marescotti, Marco van der Toorn, Manuel C. Peitsch, Carine Poussin, Walter K. Schlage
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 120
Cigarette smoking causes cardiovascular diseases. Heating tobacco instead of burning it reduces the amount of toxic compounds in the aerosol and may exert a reduced impact on health compared with cigarette smoke. Aqueous extract from the aerosol of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e99f1474dd47de099361a9f0e58a7ea
https://pubmed.ncbi.nlm.nih.gov/30026091
https://pubmed.ncbi.nlm.nih.gov/30026091
Autor:
Karsta Luettich, Yang Xiang, Anita Iskandar, Alain Sewer, Florian Martin, Marja Talikka, Patrick Vanscheeuwijck, An Berges, Emilija Veljkovic, Ignacio Gonzalez-Suarez, Walter Schlage, Julia Hoeng, Manuel Peitsch
Publikováno v:
Interdisciplinary Toxicology, Vol 7, Iss 2, Pp 73-84 (2014)
Interdisciplinary Toxicology
Interdisciplinary Toxicology
The A/J mouse is highly susceptible to lung tumor induction and has been widely used as a screening model in carcinogenicity testing and chemoprevention studies. However, the A/J mouse model has several disadvantages. Most notably, it develops lung t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ac40b35e0eca2c43dd20c903951850a
https://doaj.org/article/ad6c6f80942d4931bd35c9a9358c79cd
https://doaj.org/article/ad6c6f80942d4931bd35c9a9358c79cd
Autor:
Ignacio Gonzalez-Suarez, Julia Hoeng, S. Acali, Christopher Proctor, Paul Walker, Mark Taylor, Stefan Frentzel, Vincenzo Belcastro, Florian Martin, Manuel C. Peitsch, David Thorne, Diego Marescotti, Marianna Gaça
Publikováno v:
Toxicology Letters. 295:S237-S238
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eec99de056e966ed85394ce79c829562
https://doi.org/10.1016/j.toxlet.2018.06.989
https://doi.org/10.1016/j.toxlet.2018.06.989
Autor:
Sree C. Yaddanapudi, Teresa Ramon y Cajal, Adriana Dusso, Martin A. Neumann, David A Grotsky, Ignacio Gonzalez-Suarez, Junran Zhang, Abena B. Redwood, Xavier Matias-Guiu, Zhihui Feng, Sylvia Ortega-Martínez, Enrique Lerma, Monica Croke, Montserrat Martínez-Alonso, Susana Gonzalo, Anna Novell
Publikováno v:
The Journal of Cell Biology
Recercat. Dipósit de la Recerca de Catalunya
instname
Repositorio Abierto de la UdL
Universitad de Lleida
Recercat. Dipósit de la Recerca de Catalunya
instname
Repositorio Abierto de la UdL
Universitad de Lleida
Cathepsin L degrades 53BP1 to overcome genomic instability and growth arrest in BRCA1-deficient and triple-negative breast cancers.
Loss of 53BP1 rescues BRCA1 deficiency and is associated with BRCA1-deficient and triple-negative breast cancers
Loss of 53BP1 rescues BRCA1 deficiency and is associated with BRCA1-deficient and triple-negative breast cancers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7043d3d4e9bf504d21f83d81b1917559
https://doi.org/10.1083/jcb.201204053
https://doi.org/10.1083/jcb.201204053
Autor:
Ignacio Gonzalez Suarez, Stefano Acali, Alexandra Laurent, Diego Marescotti, Julia Hoeng, Stephanie Johne, Stefan Frentzel, Manuel C. Peitsch
Publikováno v:
Journal of Visualized Experiments : JoVE
Cigarette smoke (CS) is a major risk factor for cardiovascular and lung diseases. Because CS is a complex aerosol containing more than 7,000 chemicals1 it is challenging to assess the contributions of individual constituents to its overall toxicity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::808217a680d98dff070d6322baa2eab2
https://doi.org/10.3791/53987-v
https://doi.org/10.3791/53987-v
Nutraceuticals are food constituents with potential health benefits beyond their nutritional value. In vitro and in vivo studies suggest a protective effect of nutraceuticals against chronic diseases, but the results are not supported fully by clinic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::989d860a8b3d89463241933901087001
https://doi.org/10.1016/b978-0-12-802147-7.00022-x
https://doi.org/10.1016/b978-0-12-802147-7.00022-x
