Zobrazeno 1 - 10
of 199
pro vyhledávání: '"Ignacio Fita"'
Autor:
Leonardo Matías Cullari, Sebastián Senes, Juan Pablo Taleb, Ignacio Fita, Pablo Daniel Sarmiento
Publikováno v:
Revista de la Asociación Argentina de Ortopedia y Traumatología, Vol 87, Iss 3, Pp 360-370 (2022)
El tumor mesenquimático fosfatúrico es una entidad clinicopatológica sumamente infrecuente. Además de provocar dolor óseo insidioso y polimialgias, se acompaña de alteraciones del metabolismo fosfocálcico de difícil manejo clínico. El aborda
Externí odkaz:
https://doaj.org/article/79fba34687724e59940e421ce88105f7
Autor:
David Vizarraga, Akihiro Kawamoto, U. Matsumoto, Ramiro Illanes, Rosa Pérez-Luque, Jesús Martín, Rocco Mazzolini, Paula Bierge, Oscar Q. Pich, Mateu Espasa, Isabel Sanfeliu, Juliana Esperalba, Miguel Fernández-Huerta, Margot P. Scheffer, Jaume Pinyol, Achilleas S. Frangakis, Maria Lluch-Senar, Shigetarou Mori, Keigo Shibayama, Tsuyoshi Kenri, Takayuki Kato, Keiichi Namba, Ignacio Fita, Makoto Miyata, David Aparicio
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Adhesion of the human pathogen Mycoplasma pneumoniae to pulmonary epithelial cells is mediated by a transmembrane complex composed of proteins P1 and P40/P90. Here, the authors present the structures of M. pneumoniae P1 and P40/P90, show that P40/P90
Externí odkaz:
https://doaj.org/article/9e9188a33fb8400799815eefcf25e6bb
Autor:
David Aparicio, Margot P. Scheffer, Marina Marcos-Silva, David Vizarraga, Lasse Sprankel, Mercè Ratera, Miriam S. Weber, Anja Seybert, Sergi Torres-Puig, Luis Gonzalez-Gonzalez, Julian Reitz, Enrique Querol, Jaume Piñol, Oscar Q. Pich, Ignacio Fita, Achilleas S. Frangakis
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
The adhesion complex (Nap) in Mycoplasma genitalium is composed of the adhesin proteins P110 and P140 and essential for infectivity, motility and adhesion of this human pathogen. Here, the author present the structures of P140 alone and the P140/P110
Externí odkaz:
https://doaj.org/article/1f268fe3a2fb4fb0a415fbb67e95e782
Autor:
Ekaitz Errasti-Murugarren, Joana Fort, Paola Bartoccioni, Lucía Díaz, Els Pardon, Xavier Carpena, Meritxell Espino-Guarch, Antonio Zorzano, Christine Ziegler, Jan Steyaert, Juan Fernández-Recio, Ignacio Fita, Manuel Palacín
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
L-Amino acid Transporters (LATs) are asymmetric amino acid exchangers. Here the authors determine the crystal structure of a prokaryotic LAT, the alanine-serine-cysteine exchanger (BasC) and identify key residues for asymmetric substrate interaction
Externí odkaz:
https://doaj.org/article/02f00387781745f491d1d369e1db2215
Autor:
David Aparicio, Sergi Torres-Puig, Mercè Ratera, Enrique Querol, Jaume Piñol, Oscar Q. Pich, Ignacio Fita
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
How the Mycoplasma genitalium cytadhesins P140 and P110 promote host cell invasion remains poorly understood. Here, combining structural analysis with functional assays, Aparicio et al. identify the P110 domain that binds to sialylated receptors esse
Externí odkaz:
https://doaj.org/article/9cb10b9b3ad9431bbf28f1f147614855
Autor:
Peter C. Loewen, P. Malaka De Silva, Lynda J. Donald, Jacek Switala, Jacylyn Villanueva, Ignacio Fita, Ayush Kumar
Publikováno v:
ACS Omega, Vol 3, Iss 4, Pp 4213-4219 (2018)
Externí odkaz:
https://doaj.org/article/65cfa322468b4ed0a88d4254d74cab65
Publikováno v:
Revista de la Asociación Argentina de Ortopedia y Traumatología, Vol 80, Iss 3, Pp 164-170 (2015)
Backgraund There are different treatment for painful bone metastases (mtts), with different results. CT-guided Percutaneous Radiofrequency Ablation (CT-PRA) is one of them. The pupose of this retrospective study was to assess the initial results usi
Externí odkaz:
https://doaj.org/article/f31b3a3828dd46559c43d6b89bbbfa98
Autor:
Luca Martinelli, Luis García-Morales, Enrique Querol, Jaume Piñol, Ignacio Fita, Bárbara M Calisto
Publikováno v:
PLoS Pathogens, Vol 12, Iss 4, p e1005533 (2016)
The emergent human pathogen Mycoplasma genitalium, with one of the smallest genomes among cells capable of growing in axenic cultures, presents a flask-shaped morphology due to a protrusion of the cell membrane, known as the terminal organelle, that
Externí odkaz:
https://doaj.org/article/affd771bb15d453cbcfb17bb69e936bb
Publikováno v:
AIP Advances, Vol 6, Iss 3, Pp 035020-035020-12 (2016)
As a consequence of thermal motion, inter-atomic distances in proteins fluctuate strongly around their average values, and hence, also interaction energies (i.e. the pair-potentials evaluated at the fluctuating distances) are not constant in time but
Externí odkaz:
https://doaj.org/article/a2a2aa2be9c6497998ba1973f7d06086
Publikováno v:
Entropy, Vol 20, Iss 8, p 580 (2018)
Popcoen is a method for configurational entropy estimation of proteins based on machine-learning. Entropy is predicted with an artificial neural network which was trained on simulation trajectories of a large set of representative proteins. Popcoen i
Externí odkaz:
https://doaj.org/article/d424b93ba58f4446b47eebd52094bbf9