Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ignacio Fernandez-Sainz"'
Autor:
Elizabeth Ramirez-Medina, Lawrence K. Silbart, Teresa de los Santos, Ignacio Fernandez-Sainz, Steven M. Szczepanek, Ping Wu, Yelitza Y. Rodriguez, Tyler D Gavitt, Marla Koster
Publikováno v:
Vaccine. 37:3435-3442
Foot and Mouth Disease is a highly contagious and economically important disease of livestock. While vaccination is often effective at controlling viral spread, failures can occur due to strain mismatch or viral mutation. Foot and Mouth Disease Virus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbf259b4975396da1cb7442dde0a381d
https://doi.org/10.1016/j.vaccine.2019.05.019
https://doi.org/10.1016/j.vaccine.2019.05.019
Autor:
Ignacio Fernandez-Sainz, Teresa de los Santos, Marvin J. Grubman, Gisselle N. Medina, Marla Koster, Elizabeth Ramirez-Medina
Publikováno v:
Virology. 502:123-132
A human adenovirus (Ad5) vectored foot-and-mouth disease virus (FMDV) O1-Manisa subunit vaccine (Ad5-O1Man) was engineered to deliver FMDV O1-Manisa capsid and capsid-processing proteins. Swine inoculated with Ad5-O1Man developed an FMDV-specific hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7c0f39e51e24bbcc2ac9897fe619a2f
https://doi.org/10.1016/j.virol.2016.12.021
https://doi.org/10.1016/j.virol.2016.12.021
Autor:
Douglas P. Gladue, V. O׳Donnell, Z. Lu, Manuel V. Borca, Brenton Sanford, Ignacio Fernandez-Sainz, Lauren G. Holinka, Guillermo R. Risatti, Jolene Carlson
Publikováno v:
Virology. :13-18
Controlling classical swine fever (CSF) involves vaccination in endemic regions and preemptive slaughter of infected swine herds during epidemics. Live attenuated marker vaccines that confer effective protection against the disease and allow differen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1aa0f25016e01eeb0d5df5bc848090c
Autor:
Vivian O'Donnell, Lucas B. Carey, Lauren G. Holinka, José L. Nieva, X. Lu, Manuel V. Borca, Douglas P. Gladue, Ignacio Fernandez-Sainz, P. Fletcher, Eneko Largo
Publikováno v:
Virology. :121-130
E2, along with E(rns) and E1, is an envelope glycoprotein of Classical Swine Fever Virus (CSFV). E2 is involved in several virus functions: cell attachment, host range susceptibility and virulence in natural hosts. Here we evaluate the role of a spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e0003371ef132c369f3ead4c6390d67
Autor:
Juan M. Pacheco, Z. Lu, Manuel V. Borca, R. Baker-Branstetter, Luis L. Rodriguez, Ignacio Fernandez-Sainz, E. Brocchi, Lauren G. Holinka, Barry Baxt, Vivian O'Donnell, Douglas P. Gladue, Maria E. Piccone
Publikováno v:
Journal of Virology. 86:12080-12090
Foot-and-mouth disease virus (FMDV), the causative agent of foot-and-mouth disease, is an Apthovirus within the Picornaviridae family. Replication of the virus occurs in association with replication complexes that are formed by host cell membrane rea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe61245ef09d1b80b32a9768d360adc6
https://doi.org/10.1128/jvi.01610-12
https://doi.org/10.1128/jvi.01610-12
Autor:
Guillermo R. Risatti, Ignacio Fernandez-Sainz, Lauren G. Holinka, Manuel V. Borca, Boris Gavrilov, Kara Rogers
Publikováno v:
Virology. 420(2):135-145
Classical swine fever virus (CSFV) harbors three envelope glycoproteins (E(rns), E1 and E2). Previous studies have demonstrated that removal of specific glycosylation sites within these proteins yielded attenuated and immunogenic CSFV mutants. Here w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9042257859539a0b3bfa9b48ab8ff807
Autor:
Manuel V. Borca, Boris Gavrilov, Vivian O'Donnell, Lauren G. Holinka, Nino G. Vepkhvadze, Guillermo R. Risatti, Ignacio Fernandez-Sainz, Kara Rogers, Douglas P. Gladue
Publikováno v:
Virology. 411(1):41-49
Classical swine fever (CSF) is a highly contagious and often fatal disease of swine caused by CSF virus (CSFV), a positive-sense single-stranded RNA virus within the Pestivirus genus of the Flaviviridae family. Here, we have identified conserved sequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::657414dbfea55982a7ed1a42b28f95c2
Autor:
Guillermo R. Risatti, Lauren G. Holinka, Douglas P. Gladue, Ignacio Fernandez-Sainz, M.V. Prarat, V. O'Donell, Kara Rogers, Z. Lu, Manuel V. Borca, N. Vepkhvadze
Publikováno v:
Virology. 407(1):129-136
Here we have identified host cell proteins involved with the cellular SUMOylation pathway, SUMO-1 (small ubiquitin-like modifier) and UBC9, a SUMO-1 conjugating enzyme that interact with classical swine fever virus (CSFV) Core protein. Five highly co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab735c336ed3eaaa611e55e7e9359849
Autor:
Vivian O'Donnell, Manuel V. Borca, Lauren G. Holinka, James Zhu, Douglas P. Gladue, Consuelo Carrillo, Ignacio Fernandez-Sainz, M.V. Prarat
Publikováno v:
Virus Research. 151:10-18
Infection of domestic swine with highly virulent, classical swine fever virus (CSFV) strain Brescia, causes lethal disease in all infected animals. However, the molecular mechanisms involved in modulating the host cellular processes and evasion of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a230ea3800a06a156f83775d0b3b6f34
https://doi.org/10.1016/j.virusres.2010.03.007
https://doi.org/10.1016/j.virusres.2010.03.007
Autor:
Manuel V. Borca, Ingigerdur Gudmundsdottir, Lauren G. Holinka, Ignacio Fernandez-Sainz, Guillermo R. Risatti
Publikováno v:
Virus Research. 138:89-96
Experimental exposure of swine to highly virulent classical swine fever virus (CSFV) strain Brescia causes an invariably fatal disease of all infected animals by 8-14 days post-infection. Host mechanisms involved in this severe outcome of infection h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80bba1368d9318a2ad2f26e5c75894ae
https://doi.org/10.1016/j.virusres.2008.08.009
https://doi.org/10.1016/j.virusres.2008.08.009