Fig S6 from Inflammation Mediates the Development of Aggressive Breast Cancer Following Radiotherapy

Autor: Mary Helen Barcellos-Hoff, William Chou, Ignacio Fernandez-Garcia, Yinghao Wang, Gregor Krings, Kathleen C. Horst, Irineu Illa-Bochaca, Haoxu Ouyang, Yufei Zheng, Alba Gonzalez-Junca, Lin Ma

Supplementary Figure 6. Representative images of immune cells infiltration and proliferating cells.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d0f0ea6e859cf9f79f9b54d6efc5f9d
https://doi.org/10.1158/1078-0432.22480142

Data from Inflammation Mediates the Development of Aggressive Breast Cancer Following Radiotherapy

Autor: Mary Helen Barcellos-Hoff, William Chou, Ignacio Fernandez-Garcia, Yinghao Wang, Gregor Krings, Kathleen C. Horst, Irineu Illa-Bochaca, Haoxu Ouyang, Yufei Zheng, Alba Gonzalez-Junca, Lin Ma

Purpose:Women treated with radiotherapy before 30 years of age have increased risk of developing breast cancer at an early age. Here, we sought to investigate mechanisms by which radiation promotes aggressive cancer.Experimental Design:The tumor micr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4800a0dad0061b79c3e6e5002fcfa666
https://doi.org/10.1158/1078-0432.c.6530381.v1

Altered regulation of BRCA1 exon 11 splicing is associated with breast cancer risk in carriers of BRCA1 pathogenic variants

Autor: Gemo, Francesca Mateo, Mads Thomassen, Cimba, Daniel Jimenez, Julio Castaño, Miquel Angel Pujana, Diana Baralle, Antonis C. Antoniou, Laure Barjhoux, Carmen Herranz, Joan Brunet, Sylvie Mazoyer, Luis Palomero, Núria Bonifaci, Conxi Lázaro, Gorka Ruiz de Garibay, Paolo Radice, Eduardo Eyras, Roderic Espín, Miguel de la Hoya, Antonio Gomez, Angel Raya, Daniel R. Barnes, Nadia García, Ana I. Extremera, Xose S. Puente, Ignacio Fernandez-Garcia, Sangeeta Haydeliz Martinez-Ruiz, Pietro Ameri, Flávia Leme de Calais, Mary Helen Barcellos-Hoff, Amanda B. Spurdle, Francesca Damiola, Lars v. B. Andersen

Publikováno v: Ruiz de Garibay, G, Fernandez-Garcia, I, Mazoyer, S, Leme de Calais, F, Ameri, P, Vijayakumar, S, Martinez-Ruiz, H, Damiola, F, Barjhoux, L, Thomassen, M, Andersen, L V B, Herranz, C, Mateo, F, Palomero, L, Espín, R, Gómez, A, García, N, Jimenez, D, Bonifaci, N, Extremera, A I, Castaño, J, Raya, A, Eyras, E, Puente, X S, Brunet, J, Lázaro, C, Radice, P, Barnes, D R, Antoniou, A C, Spurdle, A B, de la Hoya, M, Baralle, D, Barcellos-Hoff, M H, Pujana, M A, GEMO & CIMBA 2021, ' Altered regulation of BRCA1 exon 11 splicing is associated with breast cancer risk in carriers of BRCA1 pathogenic variants ', Human Mutation, vol. 42, no. 11, pp. 1488-1502 . https://doi.org/10.1002/humu.24276

Germline pathogenic variants in BRCA1 confer a high risk of developing breast and ovarian cancer. The BRCA1 exon 11 (formally exon 10) is one of the largest exons and codes for the nuclear localization signals of the corresponding gene product. This

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5ada5d48d4e12a7d4f5f998f5c0f1ac
https://www.repository.cam.ac.uk/handle/1810/327476

Evaluation of smartphone-based testing to generate exploratory outcome measures in a phase 1 Parkinson's disease clinical trial

Autor: Timothy Kilchenmann, Lynne Verselis, Liping Jin, Christian Gossens, Michael Lindemann, Andreas U. Monsch, Detlef Wolf, Ronald B. Postuma, Jay Soto, Wei-Yi Cheng, Anirvan Ghosh, Frank G. Boess, Michael Grundman, Martin Koller, Alf Scotland, Florian Lipsmeier, Thomas Kremer, Kirsten I. Taylor, Juliane Siebourg-Polster, Ignacio Fernandez‐Garcia, Jens Schjodt-Eriksen, Christian Czech

Publikováno v: Movement Disorders. 33:1287-1297

Background: Ubiquitous digital technologies such as smartphone sensors promise to fundamentally change biomedical research and treatment monitoring in neurological diseases such as PD, creating a new domain of digital biomarkers. Objectives: The pres

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b6085532f1c36de644a7638a98c6cac6
https://doi.org/10.1002/mds.27376

Smartphone-based continuous mobility monitoring of Parkinsons disease patients reveals impacts of ambulatory bout length on gait features

Autor: Ignacio Fernandez Garcia, Florian Lipsmeier, Michael Lindemann, Liping Jin, Detlef Wolf, Timothy Kilchenmann, Jens Schjodt-Eriksen, Kirsten I. Taylor, Christian Gossens, Wei-Yi Cheng, Meret Martin Facklam, Andreas U. Monsch, Martin Koller, Alf Scotland, Lynne Verselis, Yan-Ping Zhang-Schaerer, Andrew P. Creagh, Juliane Siebourg-Polster, Anirvan Ghosh, Christian Czech, Thomas Kremer, Jay Soto, Michael Grundman, Frank G. Boess, Ronald B. Postuma

Publikováno v: 2017 IEEE Life Sciences Conference (LSC).

Smartphone-based remote monitoring is a potential solution for providing long-term, objective assessment of gait and mobility in patients with Parkinsons disease (PD). In the Multiple Ascending Dose study of PRX002/RG7935, forty-four mild to moderate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3505d00bc0574b31c9968f3c87109ae4
https://doi.org/10.1109/lsc.2017.8268169