Selection from a pool of self-assembling lipid replicators

Autor: Ignacio Colomer, Arseni Borissov, Stephen P. Fletcher

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)

Selection in compartmentalized self-replicating systems might provide a way for life to arise from abiotic environments. Here, the authors explore selection in a system of transient autocatalytic lipids and find that autocatalytic kinetics and phase

Externí odkaz: https://doaj.org/article/0306c7619b54490d88844fe7ccf72ba4

A transient self-assembling self-replicator

Autor: Ignacio Colomer, Sarah M. Morrow, Stephen P. Fletcher

Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-6 (2018)

Understanding self-replication and persistence in an out-of-equilibrium state is key to designing systems with new properties mimicking “living systems”. Here, the authors developed a synthetic small molecule system in which a transient surfactan

Externí odkaz: https://doaj.org/article/fd802c3a666941ffa5e6caeea2cd4d05

New antimicrobial self-assembling short lipopeptides

Autor: César Vicente-García, Ignacio Colomer

Publikováno v: Repositorio Institucional del Instituto Madrileño de Estudios Avanzados en Nanociencia
instname
Digital.CSIC. Repositorio Institucional del CSIC

Lipopeptides are an exceptional example of amphiphilic molecules that self-assemble into functional structures with applications in the areas of nanotechnology, catalysis or medicinal chemistry. Herein, we report a library of 21 short lipopeptides, t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce584632c71140d77387c8a3f804e8c5
https://doi.org/10.1039/d1ob01227d

Persistent post-discharge symptoms after COVID-19 in rheumatic and musculoskeletal diseases

Autor: Leticia Leon, Ines Perez-Sancristobal, Alfredo Madrid, Leticia Lopez-Pedraza, Jose Ignacio Colomer, Sergio Lerma, Pia Lois, Arkaitz Mucientes, Luis Rodriguez-Rodriguez, Benjamin Fernandez-Gutierrez, Lydia Abasolo

Publikováno v: Rheumatology advances in practice. 6(1)

Objectives We aimed to describe persistent symptoms and sequelae in patients with rheumatic and musculoskeletal diseases (RMD) after admission owing to coronavirus disease 2019 (COVID-19), assessing the role of autoimmune rheumatic diseases (ARDs) co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d36a47939b6fb69c7c659bd525ca679b
https://pubmed.ncbi.nlm.nih.gov/35233480

Hypervalent iodine initiated intramolecular alkene dimerisation: a stereodivergent entry to cyclobutanes

Autor: Yuxiang Zhu, Timothy J. Donohoe, Ignacio Colomer

Publikováno v: Chemical Communications. 55:10316-10319

The emergence of new methods for the stereoselective synthesis of strained carbocycles is a challenging but worthwhile endeavour. Cyclobutanes, in particular, have attracted the attention of both medicinal chemists and material scientists for their u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66b15fa0735e6101b4350c987b3e0afa
https://doi.org/10.1039/c9cc04383g