Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Ignacio Baselga"'
Autor:
Sameeha Jilani, Justin D. Saco, Edurne Mugarza, Aleida Pujol-Morcillo, Jeffrey Chokry, Clement Ng, Gabriel Abril-Rodriguez, David Berger-Manerio, Ami Pant, Jane Hu, Rubi Gupta, Agustin Vega-Crespo, Ignacio Baselga-Carretero, Jia M. Chen, Daniel Sanghoon Shin, Philip Scumpia, Roxana A. Radu, Yvonne Chen, Antoni Ribas, Cristina Puig-Saus
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract A major limitation to developing chimeric antigen receptor (CAR)-T cell therapies for solid tumors is identifying surface proteins highly expressed in tumors but not in normal tissues. Here, we identify Tyrosinase Related Protein 1 (TYRP1) a
Externí odkaz:
https://doaj.org/article/cd2701d25f8e48e2a9b53f8ebd1a39b3
Autor:
Arun Singh, Begoña Comin-Anduix, Antoni Ribas, Beata Berent-Maoz, Theodore Scott Nowicki, Luke Frankiw, Cole Peters, Mignonette Macabali, Kiana Shammaie, Crystal Quiros, Paula Kaplan-Lefko, Ignacio Baselga Carretero
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 5 (2023)
Background The tumor antigen NY-ESO-1 has been shown to be an effective target for transgenic adoptive cell therapy (ACT) for the treatment of sarcoma and melanoma. However, despite frequent early clinical responses, many patients ultimately develop
Externí odkaz:
https://doaj.org/article/bdb959ecdff84f8485d422907659729b
Akademický článek
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Autor:
Luke Frankiw, Arun Singh, Cole Peters, Begoña Comin-Anduix, Beata Berent-Maoz, Mignonette Macabali, Kiana Shammaie, Crystal Quiros, Paula Kaplan-Lefko, Ignacio Baselga Carretero, Antoni Ribas, Theodore Scott Nowicki
Publikováno v:
Journal for immunotherapy of cancer, vol 11, iss 5
BackgroundThe tumor antigen NY-ESO-1 has been shown to be an effective target for transgenic adoptive cell therapy (ACT) for the treatment of sarcoma and melanoma. However, despite frequent early clinical responses, many patients ultimately develop p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e3975fbe7927d123fc9aeb35e4d3d63
https://escholarship.org/uc/item/7262q1p4
https://escholarship.org/uc/item/7262q1p4
Autor:
Antoni Ribas, Cristina Puig-Saus, Begoña Comin-Anduix, Jas Singh, Ignacio Baselga-Carretero, Ivan Perez-Garcilazo, Ameya S. Champhekar, Mildred Galvez, Justin D. Saco, Egmidio Medina, Katie M. Campbell, Daniel Karin, Davis Y. Torrejon, Gabriel Abril-Rodriguez
Supplemental Table 3: Differential gene expression analysis between B16 KO and WT tumors in vivo at day 6. Showing genes with q < 0.05 and log2FC > 1 or < -1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05e80c04f0c12e19698320b399bff3a9
https://doi.org/10.1158/2767-9764.22545384.v1
https://doi.org/10.1158/2767-9764.22545384.v1
Autor:
Antoni Ribas, Cristina Puig-Saus, Begoña Comin-Anduix, Jas Singh, Ignacio Baselga-Carretero, Ivan Perez-Garcilazo, Ameya S. Champhekar, Mildred Galvez, Justin D. Saco, Egmidio Medina, Katie M. Campbell, Daniel Karin, Davis Y. Torrejon, Gabriel Abril-Rodriguez
Supplementary Figure 1: Impact of PAK4 deletion on the expression of chemokines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76402880d9576bbdd20804bc50e255e1
https://doi.org/10.1158/2767-9764.22545420.v1
https://doi.org/10.1158/2767-9764.22545420.v1
Autor:
Antoni Ribas, Cristina Puig-Saus, Begoña Comin-Anduix, Jas Singh, Ignacio Baselga-Carretero, Ivan Perez-Garcilazo, Ameya S. Champhekar, Mildred Galvez, Justin D. Saco, Egmidio Medina, Katie M. Campbell, Daniel Karin, Davis Y. Torrejon, Gabriel Abril-Rodriguez
Supplementary Figure 8: PAK4 KO in human melanoma cells impairs B-catenin/WNT signalling.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32c3b389b4b7844b3ae857ac44bbd96c
https://doi.org/10.1158/2767-9764.22545396.v1
https://doi.org/10.1158/2767-9764.22545396.v1
Autor:
Antoni Ribas, Cristina Puig-Saus, Begoña Comin-Anduix, Jas Singh, Ignacio Baselga-Carretero, Ivan Perez-Garcilazo, Ameya S. Champhekar, Mildred Galvez, Justin D. Saco, Egmidio Medina, Katie M. Campbell, Daniel Karin, Davis Y. Torrejon, Gabriel Abril-Rodriguez
Supplementary Figure 4: PAK4 deletion does not affect MHC-I and II surface expression.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4f39e0333f00a4b54646d5862e59157
https://doi.org/10.1158/2767-9764.22545408
https://doi.org/10.1158/2767-9764.22545408
Autor:
Antoni Ribas, Cristina Puig-Saus, Begoña Comin-Anduix, Jas Singh, Ignacio Baselga-Carretero, Ivan Perez-Garcilazo, Ameya S. Champhekar, Mildred Galvez, Justin D. Saco, Egmidio Medina, Katie M. Campbell, Daniel Karin, Davis Y. Torrejon, Gabriel Abril-Rodriguez
Supplemental Table 6: List of extracellular matrix genes enriched in PAK4 KO anti-PD-1 treated samples.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a23a219ce431825e9d28ac0619689027
https://doi.org/10.1158/2767-9764.22545375.v1
https://doi.org/10.1158/2767-9764.22545375.v1
Autor:
Antoni Ribas, Cristina Puig-Saus, Begoña Comin-Anduix, Jas Singh, Ignacio Baselga-Carretero, Ivan Perez-Garcilazo, Ameya S. Champhekar, Mildred Galvez, Justin D. Saco, Egmidio Medina, Katie M. Campbell, Daniel Karin, Davis Y. Torrejon, Gabriel Abril-Rodriguez
Supplementary Figure 2: PAK4 deletion does not affect CCL21 secretion.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1911b938965880825a5a0fcc80251d50
https://doi.org/10.1158/2767-9764.22545414
https://doi.org/10.1158/2767-9764.22545414