Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Ignacio, Casanova"'
Autor:
María Inmaculada Domínguez-Mozo, Ignacio Casanova, Enric Monreal, Lucienne Costa-Frossard, Susana Sainz-de-la-Maza, Raquel Sainz-Amo, Yolanda Aladro-Benito, Pedro Lopez-Ruiz, Laura De-Torres, Sara Abellán, Maria Angel Garcia-Martinez, David De-la-Cuesta, Daniel Lourido, Angel Torrado, Carol Gomez-Barbosa, Carla Linares-Villavicencio, Luisa Maria Villar, Carlos López-De-Silanes, Rafael Arroyo, Roberto Alvarez-Lafuente
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 18, p 10012 (2024)
microRNAs (miRNAs) are promising biomarkers for many diseases, including multiple sclerosis (MS). The neurofilament light chain (NfL) is a biomarker that can detect axonal damage in different neurological diseases. The objective of this study was to
Externí odkaz:
https://doaj.org/article/17d2b96e5ede433b9a6a38e72254449e
Autor:
Ignacio Casanova-Maldonado, David Arancibia, Pablo Lois, Isaac Peña-Villalobos, Verónica Palma
Publikováno v:
Biological Research, Vol 56, Iss 1, Pp 1-15 (2023)
Abstract Background Hyperbaric oxygen treatment (HBOT) has been reported to modulate the proliferation of neural and mesenchymal stem cell populations, but the molecular mechanisms underlying these effects are not completely understood. In this study
Externí odkaz:
https://doaj.org/article/d12c81af98e84ec1beabbb4dd3582da9
Autor:
María Inmaculada Domínguez-Mozo, Inés González-Suárez, Luisa María Villar, Lucienne Costa-Frossard, Noelia Villarrubia, Yolanda Aladro, Belén Pilo, Xavier Montalbán, Manuel Comabella, Ignacio Casanova-Peño, María Luisa Martínez-Ginés, Jose Manuel García-Domínguez, María Ángel García-Martínez, Rafael Arroyo, Roberto Álvarez-Lafuente
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundEpstein–Barr virus (EBV) and human herpesvirus 6 (HHV-6) have been associated with multiple sclerosis (MS). Teriflunomide is an oral disease-modifying therapy approved for treatment of relapsing forms of MS. In the preclinical Theiler’s
Externí odkaz:
https://doaj.org/article/932dbd9284cf433081432ebfa5ee9061
Autor:
Ignacio Casanova, María I. Domínguez-Mozo, Laura De Torres, Yolanda Aladro-Benito, Ángel García-Martínez, Patricia Gómez, Sara Abellán, Esther De Antonio, Roberto Álvarez-Lafuente
Publikováno v:
Biomedicines, Vol 11, Iss 10, p 2760 (2023)
MicroRNAs (miRNAs) are promising biomarkers in multiple sclerosis (MS). This study aims to investigate the association between a preselected list of miRNAs in serum with therapeutic response to Glatiramer Acetate (GA) and with the clinical evolution
Externí odkaz:
https://doaj.org/article/1b3e85de95714989b34cd963f2acf653
Autor:
María I. Dominguez-Mozo, Ignacio Casanova, Laura De Torres, Yolanda Aladro-Benito, Silvia Perez-Perez, Angel Garcia-Martínez, Patricia Gomez, Sara Abellan, Esther De Antonio, Carlos Lopez-De-Silanes, Roberto Alvarez-Lafuente
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundMicroRNAs are small non-coding RNA that regulate gene expression at a post-transcriptional level affecting several cellular processes including inflammation, neurodegeneration and remyelination. Different patterns of miRNAs expression have
Externí odkaz:
https://doaj.org/article/83c40f2fc4ba4b71be66408652f7e4a4
Publikováno v:
Revista Discapacidad, Clínica, Neurociencias, Vol 7, Iss 1, Pp 27-39 (2020)
La esclerosis múltiple (EM) es una enfermedad crónica y neurodegenerativa del Sistema Nervioso Central con clara prevalencia de alteraciones cognitivas, especialmente atención, memoria y funciones ejecutivas. Los estudios de volumetría han mostra
Externí odkaz:
https://doaj.org/article/e7b9b8c25a354fa9b3cb64f9e5821fab
Autor:
Adela González-Jiménez, Pilar López-Cotarelo, Teresa Agudo-Jiménez, Ignacio Casanova, Carlos López de Silanes, Ángeles Martín-Requero, Fuencisla Matesanz, Elena Urcelay, Laura Espino-Paisán
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8116 (2022)
Deficiencies in Mannosidase β (MANBA) are associated with neurological abnormalities and recurrent infections. The single nucleotide polymorphism located in the 3′UTR of MANBA, rs7665090, was found to be associated with multiple sclerosis (MS) sus
Externí odkaz:
https://doaj.org/article/afa46f33edc84a28b972a5797ccb10d9
Publikováno v:
Frontiers in Physiology, Vol 9 (2019)
Several studies have evaluated plastic changes in the morphology of the digestive tract in rodents subjected to caloric restriction or restricted availability. Nevertheless, studies that link these morphological responses to physiological consequence
Externí odkaz:
https://doaj.org/article/c8fa6b2dce794cc6817d0833f46d7145
Autor:
Isaac Peña-Villalobos, Ignacio Casanova-Maldonado, Pablo Lois, Catalina Prieto, Carolina Pizarro, José Lattus, Germán Osorio, Verónica Palma
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Hyperbaric oxygen therapy (HBOT) is effective for the medical treatment of diverse diseases, infections, and tissue injury. In fact, in recent years there is growing evidence on the beneficial effect of HBOT on non-healing ischemic wounds. However, t
Externí odkaz:
https://doaj.org/article/01e700fbe8ab4d0ca20b87e65289635d
Autor:
Susana Sainz de la Maza, Israel Thuissard, Andy Castro, Lucienne Costa-Frossard, Carmen Muñoz, Carlos López de Silanes, Julia Sabin, Hugo Martín, Yolanda Aladro, Ignacio Casanova, Irene Moreno, M Luisa Martínez-Ginés, Mayra Gómez-Moreno, Victoria Galan, Sarai Urtiaga, Lucía Ayuso, Elena Rodríguez-García, Celia Oreja-Guevara, Belen Pilo, Pedro Sánchez, Virginia Meca-Lallana, J.A. García-Merino, Laura Borrega, Alberto Lozano, Judit Díaz-Díaz
Publikováno v:
Journal of Neurology. 267:2362-2371
Dimethyl fumarate (DMF) tolerability and safety in multiple sclerosis (MS) has been analyzed in randomized clinical trials. Real-life studies are needed to assess possible harms of this therapy in a wider MS population. To evaluate DMF tolerability,