Zobrazeno 1 - 10
of 342
pro vyhledávání: '"Ignacio, Anegon"'
Autor:
Malika Gantier, Raphaël Rispal, Angélique Fourrier, Séverine Ménoret, Frédéric Delbos, Ignacio Anegon, Tuan Huy Nguyen
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Background Liver transplantation remains the only curative treatment for end-stage liver diseases. Unfortunately, there is a drastic organ donor shortage. Hepatocyte transplantation emerged as a viable alternative to liver transplantation. C
Externí odkaz:
https://doaj.org/article/cfac51ddd42d4063929dfa42726e6562
Autor:
Caroline Le Guiner, Xiao Xiao, Thibaut Larcher, Aude Lafoux, Corinne Huchet, Gilles Toumaniantz, Oumeya Adjali, Ignacio Anegon, Séverine Remy, Josh Grieger, Juan Li, Vahid Farrokhi, Hendrik Neubert, Jane Owens, Maritza McIntyre, Philippe Moullier, R. Jude Samulski
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 30, Iss , Pp 30-47 (2023)
Duchenne muscular dystrophy (DMD) is an X-linked disease caused by loss-of-function mutations in the dystrophin gene and is characterized by muscle wasting and early mortality. Adeno-associated virus-mediated gene therapy is being investigated as a t
Externí odkaz:
https://doaj.org/article/7a89e1515ecf4452944c4318d3851f25
Autor:
Séverine Bézie, Céline Sérazin, Elodie Autrusseau, Nadège Vimond, Magali Giral, Ignacio Anegon, Carole Guillonneau
Publikováno v:
PLoS ONE, Vol 19, Iss 3, p e0300032 (2024)
Biomarkers that could predict the evolution of the graft in transplanted patients and that could allow to adapt the care of the patients would be an invaluable tool. Additionally, certain biomarkers can be target of treatments and help to stratify pa
Externí odkaz:
https://doaj.org/article/3468710732c54ac586385577f5cac0f8
Autor:
Séverine Ménoret, Laurent Tesson, Séverine Remy, Victor Gourain, Céline Sérazin, Claire Usal, Aude Guiffes, Vanessa Chenouard, Laure-Hélène Ouisse, Malika Gantier, Jean-Marie Heslan, Cynthia Fourgeux, Jeremie Poschmann, Carole Guillonneau, Ignacio Anegon
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Background Regulatory T cells (Treg) in diverse species include CD4+ and CD8+ T cells. In all species, CD8+ Treg have been only partially characterized and there is no rat model in which CD4+ and CD8+ FOXP3+ Treg are genetically tagged. Resu
Externí odkaz:
https://doaj.org/article/a5f7fd4d1ec14f8a9408162e7c0a4594
Autor:
Matthieu Leuillier, Thomas Duflot, Séverine Ménoret, Hind Messaoudi, Zoubir Djerada, Déborah Groussard, Raphaël G.P. Denis, Laurence Chevalier, Ahmed Karoui, Baptiste Panthu, Pierre-Alain Thiébaut, Isabelle Schmitz-Afonso, Séverine Nobis, Cynthia Campart, Tiphaine Henry, Camille Sautreuil, Serge H. Luquet, Olivia Beseme, Catherine Féliu, Hélène Peyret, Lionel Nicol, Jean-Paul Henry, Sylvanie Renet, Paul Mulder, Debin Wan, Laurent Tesson, Jean-Marie Heslan, Angéline Duché, Sébastien Jacques, Frédéric Ziegler, Valéry Brunel, Gilles J.P. Rautureau, Christelle Monteil, Jean-Luc do Rego, Jean-Claude do Rego, Carlos Afonso, Bruce Hammock, Anne-Marie Madec, Florence Pinet, Vincent Richard, Ignacio Anegon, Christophe Guignabert, Christophe Morisseau, Jérémy Bellien
Publikováno v:
Journal of Advanced Research, Vol 43, Iss , Pp 163-174 (2023)
Introduction: Although the physiological role of the C-terminal hydrolase domain of the soluble epoxide hydrolase (sEH-H) is well investigated, the function of its N-terminal phosphatase activity (sEH-P) remains unknown. Objectives: This study aimed
Externí odkaz:
https://doaj.org/article/ae3d2c7efa674a65a28617072bd9a0df
Autor:
Sandra Martin Lorenzo, Maria del Mar Muniz Moreno, Helin Atas, Marion Pellen, Valérie Nalesso, Wolfgang Raffelsberger, Geraldine Prevost, Loic Lindner, Marie-Christine Birling, Séverine Menoret, Laurent Tesson, Luc Negroni, Jean-Paul Concordet, Ignacio Anegon, Yann Herault
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Copy number variations (CNVs) of the human 16p11.2 locus are associated with several developmental/neurocognitive syndromes. Particularly, deletion and duplication of this genetic interval are found in patients with autism spectrum disorders, intelle
Externí odkaz:
https://doaj.org/article/e090825d4e2b438eba92293661a994d6
Autor:
Vanessa Chenouard, Isabelle Leray, Laurent Tesson, Severine Remy, Alasdair Allan, Daniel Archer, Adam Caulder, Agnès Fortun, Karine Bernardeau, Yacine Cherifi, Lydia Teboul, Laurent David, Ignacio Anegon
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106399- (2023)
Summary: CRISPR-Cas9 cleavage efficacy and accuracy are the main challenges gene editing faces, and they are particularly affected by the optimal formation of the ribonucleoprotein (RNP) complex. We used nano differential scanning fluorimetry, a labe
Externí odkaz:
https://doaj.org/article/3e4821e8ad1840e39504e69a7b2227d8
Autor:
Quentin Jouhault, Bilade Cherqaoui, Aude Jobart-Malfait, Simon Glatigny, Marc Lauraine, Audrey Hulot, Guillaume Morelle, Benjamin Hagege, Kétia Ermoza, Ahmed El Marjou, Brigitte Izac, Benjamin Saintpierre, Franck Letourneur, Séverine Rémy, Ignacio Anegon, Marie-Christophe Boissier, Gilles Chiocchia, Maxime Breban, Luiza M. Araujo
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
IntroductionSpondylarthritis (SpA) development in HLA-B27/human β2-microglobulin transgenic rat (B27-rat) is correlated with altered conventional dendritic cell (cDC) function that promotes an inflammatory pattern of CD4+T cells, including a biased
Externí odkaz:
https://doaj.org/article/2e30a7f06f474f3182838005f3013d7f
Autor:
Anna Creisméas, Claire Gazaille, Audrey Bourdon, Marc-Antoine Lallemand, Virginie François, Marine Allais, Mireille Ledevin, Thibaut Larcher, Gilles Toumaniantz, Aude Lafoux, Corinne Huchet, Ignacio Anegon, Oumeya Adjali, Caroline Le Guiner, Bodvaël Fraysse
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-17 (2021)
Abstract Background Duchenne muscular dystrophy (DMD) is an X-linked inherited disease caused by mutations in the gene encoding dystrophin that leads to a severe and ultimately life limiting muscle-wasting condition. Recombinant adeno-associated vect
Externí odkaz:
https://doaj.org/article/df4837365a234a57b360f01bc60d2a4d
Autor:
Antoine Freuchet, Apolline Salama, Séverine Bézie, Laurent Tesson, Séverine Rémy, Romain Humeau, Hadrien Règue, Céline Sérazin, Léa Flippe, Pärt Peterson, Nadège Vimond, Claire Usal, Séverine Ménoret, Jean‐Marie Heslan, Franck Duteille, Frédéric Blanchard, Magali Giral, Marco Colonna, Ignacio Anegon, Carole Guillonneau
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 8, Pp n/a-n/a (2022)
Background Immune homeostasis requires fully functional Tregs with a stable phenotype to control autoimmunity. Although IL‐34 is a cytokine first described as mainly involved in monocyte cell survival and differentiation, we recently described its
Externí odkaz:
https://doaj.org/article/66e3ea0bfcc54419864f02858ee50ceb