Renal, retinal and cardiac changes in type 2 diabetes are attenuated by macitentan, a dual endothelin receptor antagonist

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Publikováno v: In Life Sciences 15 October 2012 91(13-14):658-668

Lucerastat, an iminosugar for substrate reduction therapy in Fabry Disease: Preclinical evidence

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Fabry disease (FD) is a lysosomal storage disorder caused by mutations in the GLA gene coding for α-galactosidase A (α-GalA). These mutations lead to the accumulation of α-GalA substrates, including globotriaosylceramide (Gb3). As a consequence of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1064::92f5e9f570a26ca579ec95f0e42ee3f4
https://ora.ox.ac.uk/objects/uuid:4b6b1f50-7f47-4b1b-8acd-cfd2fd52f033

Eplerenone, a mineralocorticoid receptor inhibitor, reduces cirrhosis associated changes of hepatocyte glucose and lipid metabolism.

Autor: Mohib, Mohammad Mohabbulla¹ (AUTHOR), Rabe, Sindy¹ (AUTHOR), Nolze, Alexander¹ (AUTHOR), Rooney, Michael² (AUTHOR), Ain, Quratul² (AUTHOR), Zipprich, Alexander² (AUTHOR), Gekle, Michael¹ (AUTHOR), Schreier, Barbara^1,3 (AUTHOR) barbara.schreier@medizin.uni-halle.de

Publikováno v: Cell Communication & Signaling. 12/20/2024, Vol. 22 Issue 1, p1-18. 18p.

Arterial Hypertension: Novel Pharmacological Targets and Future Perspectives.

Autor: Popa, Irene Paula¹ (AUTHOR) dragomir.serban@umfiasi.ro, Clim, Andreea¹ (AUTHOR), Pînzariu, Alin Constantin¹ (AUTHOR) alin.pinzariu@umfiasi.ro, Lazăr, Cristina Iuliana¹ (AUTHOR), Popa, Ștefan² (AUTHOR), Tudorancea, Ivona Maria³ (AUTHOR), Moscalu, Mihaela⁴ (AUTHOR), Șerban, Dragomir N.¹ (AUTHOR), Șerban, Ionela Lăcrămioara¹ (AUTHOR), Costache-Enache, Irina-Iuliana^5,6 (AUTHOR) ii.costache@yahoo.com, Tudorancea, Ionuț^1,6 (AUTHOR)

Publikováno v: Journal of Clinical Medicine. Oct2024, Vol. 13 Issue 19, p5927. 28p.

Effects of macitentan and tadalafil monotherapy or their combination on the right ventricle and plasma metabolites in pulmonary hypertensive rats.

Autor: Mamazhakypov A; Cardio-Pulmonary Institute (CPI), Universities of Giessen and Marburg Lung Center, Member of the German Lung Center (DZL), Justus-Liebig-University Giessen, Giessen, Germany., Weiß A; Cardio-Pulmonary Institute (CPI), Universities of Giessen and Marburg Lung Center, Member of the German Lung Center (DZL), Justus-Liebig-University Giessen, Giessen, Germany., Zukunft S; Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe University, Frankfurt am Main, Germany & German Center of Cardiovascular Research (DZHK), Partner site RheinMain, Frankfurt am Main, Germany., Sydykov A; Cardio-Pulmonary Institute (CPI), Universities of Giessen and Marburg Lung Center, Member of the German Lung Center (DZL), Justus-Liebig-University Giessen, Giessen, Germany., Kojonazarov B; Cardio-Pulmonary Institute (CPI), Universities of Giessen and Marburg Lung Center, Member of the German Lung Center (DZL), Justus-Liebig-University Giessen, Giessen, Germany., Wilhelm J; Cardio-Pulmonary Institute (CPI), Universities of Giessen and Marburg Lung Center, Member of the German Lung Center (DZL), Justus-Liebig-University Giessen, Giessen, Germany., Vroom C; Cardio-Pulmonary Institute (CPI), Universities of Giessen and Marburg Lung Center, Member of the German Lung Center (DZL), Justus-Liebig-University Giessen, Giessen, Germany., Petrovic A; Cardio-Pulmonary Institute (CPI), Universities of Giessen and Marburg Lung Center, Member of the German Lung Center (DZL), Justus-Liebig-University Giessen, Giessen, Germany., Kosanovic D; Cardio-Pulmonary Institute (CPI), Universities of Giessen and Marburg Lung Center, Member of the German Lung Center (DZL), Justus-Liebig-University Giessen, Giessen, Germany.; Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia., Weissmann N; Cardio-Pulmonary Institute (CPI), Universities of Giessen and Marburg Lung Center, Member of the German Lung Center (DZL), Justus-Liebig-University Giessen, Giessen, Germany., Seeger W; Cardio-Pulmonary Institute (CPI), Universities of Giessen and Marburg Lung Center, Member of the German Lung Center (DZL), Justus-Liebig-University Giessen, Giessen, Germany.; Department of Lung Development and Remodelling, Max-Planck Institute for Heart and Lung Research, Bad Nauheim, Germany., Fleming I; Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe University, Frankfurt am Main, Germany & German Center of Cardiovascular Research (DZHK), Partner site RheinMain, Frankfurt am Main, Germany., Iglarz M; Actelion Pharmaceuticals Ltd, Allschwil, Switzerland., Grimminger F; Cardio-Pulmonary Institute (CPI), Universities of Giessen and Marburg Lung Center, Member of the German Lung Center (DZL), Justus-Liebig-University Giessen, Giessen, Germany., Ghofrani HA; Cardio-Pulmonary Institute (CPI), Universities of Giessen and Marburg Lung Center, Member of the German Lung Center (DZL), Justus-Liebig-University Giessen, Giessen, Germany., Pullamsetti SS; Cardio-Pulmonary Institute (CPI), Universities of Giessen and Marburg Lung Center, Member of the German Lung Center (DZL), Justus-Liebig-University Giessen, Giessen, Germany.; Department of Lung Development and Remodelling, Max-Planck Institute for Heart and Lung Research, Bad Nauheim, Germany., Schermuly RT; Cardio-Pulmonary Institute (CPI), Universities of Giessen and Marburg Lung Center, Member of the German Lung Center (DZL), Justus-Liebig-University Giessen, Giessen, Germany.

Publikováno v: Pulmonary circulation [Pulm Circ] 2020 Nov 11; Vol. 10 (4), pp. 2045894020947283. Date of Electronic Publication: 2020 Nov 11 (Print Publication: 2020).