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Autor:
Gerald Zon, Tim Geiser, Carlo Leonetti, Igea D' Agnano, Francesco Lozupone, Bruno Calabretta, Alessandra Valentini, Gabriella Zupi, Gennaro Citro
Publikováno v:
Journal of the National Cancer Institute. 88(7)
Background : Phosphorothioate oligodeoxynucleotides ([S]ODNs) contain a modified internucleoside phosphate backbone. Antisense [S]ODNs targeted to specific oncogenes have been used with some therapeutic success in animal models of human leukemia ; ho