Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Iga Sienczylo"'
Autor:
Omid Hamid, Melissa L. Johnson, Jason Luke, Richard T. Maziarz, Jamie Merchan, Emerson E. Lim, Sandip P. Patel, Geoffrey M. Kuesters, Iga Sienczylo, Gilad Gordon, Karen Campbell, Kristin Horton, Laurence Turka, Alexander I. Spira
Publikováno v:
Cancer Research. 82:CT187-CT187
Background: RTX-240 is an allogeneic cellular therapy genetically engineered to express high copy numbers of trimeric 4-1BBL and IL-15/IL-15Rα fusion proteins on the RBC surface membrane. RTX-240 is designed to activate and expand CD8+ memory T cell
Autor:
Omid Hamid, Jason J. Luke, Geoffrey M. Kuesters, Melissa Lynne Johnson, Iga Sienczylo, Alexander I. Spira, Gilad Gordon
Publikováno v:
Cancer Research. 81:CT141-CT141
Short title: RTX-240 phase 1 in solid tumorsA phase 1 trial of RTX-240, an allogeneic engineered red blood cell with cell -surface expression of 4-1BBL and trans-presented IL-15, in patients with advanced solid tumorsBackground: T cell checkpoint inh
Autor:
Don M. Benson, Megan M. O'Meara, Luke P. Akard, Ben Exter, Jessica Sachs, Tooba A. Cheema, Ann Ranger, Parameswaran Hari, Django Sussman, Iga Sienczylo, Houston Holmes
Publikováno v:
Blood. 132:1997-1997
Background: B cell maturation antigen (BCMA) has recently emerged as a promising candidate antigen for therapeutic targeting in multiple myeloma (MM), with several targeted agents in clinical studies including antibody-drug conjugates and bispecific