Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Ifeanyi J. Arinze"'
Autor:
Treniqka S. Walters, Deneshia J. McIntosh, Shalonda M. Ingram, Lakeisha Tillery, Evangeline D. Motley, Ifeanyi J. Arinze, Smita Misra
Publikováno v:
Cellular Physiology and Biochemistry, Vol 55, Iss 2, Pp 141-159 (2021)
Externí odkaz:
https://doaj.org/article/97c4496483ac43b18dade1b9cf9b57b6
Autor:
Andrea Flores Burroughs, Sylvia Eluhu, Diva Whalen, J. Shawn Goodwin, Amos M. Sakwe, Ifeanyi J. Arinze
Publikováno v:
Cellular Physiology and Biochemistry, Vol 47, Iss 2, Pp 800-816 (2018)
Background/Aims: Nuclear factor erythroid 2-related factor 2 (Nrf2) is a basic leucine-zipper transcription factor essential for cellular responses to oxidative stress. Degradation of Nrf2 in the cytoplasm, mediated by Keap1-Cullin3/RING box1 (Cul3-R
Externí odkaz:
https://doaj.org/article/5bce30adc77a47ee95b54b0c42989ebe
Publikováno v:
Cellular Physiology and Biochemistry, Vol 46, Iss 1, Pp 418-430 (2018)
Background/Aims: The transcription factor Nrf2 is a master regulator of the antioxidant defense system, protecting cells from oxidative damage. We previously reported that the SUMO-targeted E3 ubiquitin ligase (STUbL), RING finger protein 4 (RNF4) ac
Externí odkaz:
https://doaj.org/article/7958f914d7d14659a156f27a58d3a613
Autor:
J. Shawn Goodwin, Diva S. Whalen, Andrea Flores Burroughs, Sylvia Eluhu, Ifeanyi J. Arinze, Amos M. Sakwe
Publikováno v:
The FASEB Journal. 32
Publikováno v:
The FASEB Journal. 32
Autor:
Diva S. Whalen, Sylvia Eluhu, J. Shawn Goodwin, Andrea Flores Burroughs, Amos M. Sakwe, Ifeanyi J. Arinze
Publikováno v:
Cellular Physiology and Biochemistry, Vol 47, Iss 2, Pp 800-816 (2018)
Background/Aims: Nuclear factor erythroid 2-related factor 2 (Nrf2) is a basic leucine-zipper transcription factor essential for cellular responses to oxidative stress. Degradation of Nrf2 in the cytoplasm, mediated by Keap1-Cullin3/RING box1 (Cul3-R
Autor:
J. Shawn Goodwin, Ifeanyi J. Arinze, Deneshia McIntosh, Andrea Flores, Treniqka Walters, Melanie Theodore Malloy
Publikováno v:
Journal of Biological Chemistry. 288:14569-14583
Ubiquitylation of Nrf2 by the Keap1-Cullin3/RING box1 (Cul3-Rbx1) E3 ubiquitin ligase complex targets Nrf2 for proteasomal degradation in the cytoplasm and is an extensively studied mechanism for regulating the cellular level of Nrf2. Although mechan
Publikováno v:
Journal of Biological Chemistry. 286:7629-7640
Activation of Nrf2 by covalent modifications that release it from its inhibitor protein Keap1 has been extensively documented. In contrast, covalent modifications that may regulate its action after its release from Keap1 have received little attentio
Autor:
Frederic Bone, Ifeanyi J. Arinze, Chuan Xu, Tertius T. Tuy, Paul Ernsberger, Duna Massillon, Janean Johnson
Publikováno v:
The Journal of Nutritional Biochemistry. 19:305-312
The Koletsky (SHROB) strain of rats is spontaneously hypertensive and displays insulin resistance, hyperglucagonemia and hypertriglyceridemia but is normoglycemic under fasting conditions. The aim of this study was to unravel the pattern of expressio
Autor:
Frederic Bone, Tertius T. Tuy, Xiaoying Kong, Chuan Xu, Kaushik Chakravarty, Ifeanyi J. Arinze, Duna Massillon
Publikováno v:
The Journal of Nutrition. 137:554-559
Fatty acids and glucose are strong modulators of the expression of glucose-6-phosphatase (Glc-6-Pase), an enzyme that plays a key role in glucose homeostasis. PUFA inhibit, whereas SFA and monounsaturated fatty acids induce the expression of the Glc-