Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Ifat Cohen-Or"'
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e74970 (2013)
Advanced Glycation End Products (AGEs) are the final products of non-enzymatic protein glycation that results in loss of protein structure and function. We have previously shown that in E. coli AGEs are continually formed as high-molecular weight pro
Externí odkaz:
https://doaj.org/article/194f721b83dd47e3b1ca9712b1c9bc2d
Autor:
Adit Naor, Patrick C Thiaville, Neta Altman-Price, Ifat Cohen-Or, Thorsten Allers, Valérie de Crécy-Lagard, Uri Gophna
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43013 (2012)
KEOPS is an important cellular complex conserved in Eukarya, with some subunits conserved in Archaea and Bacteria. This complex was recently found to play an essential role in formation of the tRNA modification threonylcarbamoyladenosine (t(6)A), and
Externí odkaz:
https://doaj.org/article/7a5a9b5829c8414d9931545e6a594a7c
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17974 (2011)
Advanced Glycated End Products (AGEs) are formed by non-enzymatic protein glycation and are implicated in several physiological aspects including cell aging and diseases. Recent data indicate that bacteria--although short lived--produce, metabolize a
Externí odkaz:
https://doaj.org/article/19be41c2e1ec40a38f8e4c69db8a12e3
Publikováno v:
mBio, Vol 1, Iss 3 (2010)
ABSTRACT Amadori-modified proteins (AMPs) are the products of nonenzymatic glycation formed by reaction of reducing sugars with primary amine-containing amino acids and can develop into advanced glycated end products (AGEs), highly stable toxic compo
Externí odkaz:
https://doaj.org/article/4dddbeaac87d44d0848af6cc271f1fc6
Publikováno v:
Heliyon, Vol 10, Iss 4, Pp e26095- (2024)
Here we present the development of nanoparticles (NPs) formulations specifically designed for targeting the antiapoptotic Bcl-2 proteins on the outer membrane of mitochondria with the drug agent ABT-737. The NPs which are self-assembled by the natura
Externí odkaz:
https://doaj.org/article/799195bd891e43f9bf178cea7a01755f
Publikováno v:
Open Journal of Orthopedics and Rheumatology. :037-048
Background: Wnt signaling pathways are taking a part in regulation of cell fate decisions in normal and cancerous cells. In some cancer types, a transition from canonical to non-canonical Wnt signaling pathways was identified, a phenomenon, that in r
Publikováno v:
Clinicalexperimental metastasis. 39(5)
Despite the significant progress made over the past decade with combination of molecular profiling data and the development of new clinical strategies, our understanding of metastasis remains elusive. Bone metastasis is a complex process and a major
Autor:
Levi A. Gheber, Ifat Cohen-Erez, Brenda Laster, Yael Lavi, Jammi Milam, Ruthy Shaco-Levy, Carol Issacson, Hanna Rapaport
Publikováno v:
ACS Applied Materials & Interfaces. 11:32670-32678
Biomaterials folded into nanoparticles (NPs) can be utilized as targeted drug delivery systems for cancer therapy. NPs may provide a vehicle for the anticancer drug lonidamine (LND), which inhibits glycolysis but was suspended from use at the clinica
Publikováno v:
Polymers for Advanced Technologies. 30:2506-2514
Autor:
Blake Kazaoka, Zulfiya Orynbayeva, David E. Stein, Richard Sensenig, Hanna Rapaport, Carleigh Charles, Ifat Cohen-Erez, Olga Melnikov
Publikováno v:
Nanomedicine (London, England). 15(30)
Aims: The mechanistic study of the drug carrier–target interactions of mitochondria-unique nanoparticles composed of polypeptide–peptide complexes (mPoP-NPs). Materials & methods: The isolated organelles were employed to address the direct effect