Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ieva Usaite"'
Autor:
Yin Wu, Charles Swanton, Mihaela Angelova, Crispin Hiley, Marleen Kok, Nicolai Birkbak, Ieva Usaite, Dhruva Biswas, Krijn Dijkstra, Thomas BK Watkins, Oriol Pich, Clare Puttick, Krupa Thakkar, Simone Zaccaria, Kevin Litchfield, Nnennaya Kanu
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 11 (2023)
Background Checkpoint inhibitor (CPI) immunotherapies have provided durable clinical responses across a range of solid tumor types for some patients with cancer. Nonetheless, response rates to CPI vary greatly between cancer types. Resolving intratum
Externí odkaz:
https://doaj.org/article/da17de2de8c74189b560015ef1154a8e
Autor:
Samuel F. Bakhoum, Benjamin Izar, Eileen E. Parkes, Alexander N. Shoushtari, Charles Swanton, Olivier Elemento, Jedd D. Wolchok, Simon N. Powell, Neil Vasan, Anusha Kalbasi, Shin-San Michael Su, Nadeem Riaz, Jorge S. Reis-Filho, Hannah Y. Wen, Taha Merghoub, Travis J. Hollmann, Benjamin J. DiPardo, Lee Gottesdiener, Chantal Pauli, Peng Li, Julie-Ann Cavallo, Princesca Dorsaint, Maria Laura Martin, Hao Wei Li, Rohan Bareja, Dhruva Biswas, Ieva Usaite, Kevin Litchfield, Sreeram Vallabhaneni, Johannes C. Melms, Matthew G. Hanna, Jacqueline A. James, Manuel Salto-Tellez, Matthew P. Humphries, Roshan K. Sriram, John Kwon, Sarah E. Bettigole, Walid K. Chatila, Ninjit Dhanota, Mercedes A. Duran, Jun Li
Supplementary Figures and Methods in PDF format
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::635ea996437975f580871317155e428c
https://doi.org/10.1158/2159-8290.22540268.v1
https://doi.org/10.1158/2159-8290.22540268.v1
Autor:
Samuel F. Bakhoum, Benjamin Izar, Eileen E. Parkes, Alexander N. Shoushtari, Charles Swanton, Olivier Elemento, Jedd D. Wolchok, Simon N. Powell, Neil Vasan, Anusha Kalbasi, Shin-San Michael Su, Nadeem Riaz, Jorge S. Reis-Filho, Hannah Y. Wen, Taha Merghoub, Travis J. Hollmann, Benjamin J. DiPardo, Lee Gottesdiener, Chantal Pauli, Peng Li, Julie-Ann Cavallo, Princesca Dorsaint, Maria Laura Martin, Hao Wei Li, Rohan Bareja, Dhruva Biswas, Ieva Usaite, Kevin Litchfield, Sreeram Vallabhaneni, Johannes C. Melms, Matthew G. Hanna, Jacqueline A. James, Manuel Salto-Tellez, Matthew P. Humphries, Roshan K. Sriram, John Kwon, Sarah E. Bettigole, Walid K. Chatila, Ninjit Dhanota, Mercedes A. Duran, Jun Li
Cytosolic DNA is characteristic of chromosomally unstable metastatic cancer cells, resulting in constitutive activation of the cGAS–STING innate immune pathway. How tumors co-opt inflammatory signaling while evading immune surveillance remains unkn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af51a233154e60a4e2bb2d77e8270d96
https://doi.org/10.1158/2159-8290.c.6549335
https://doi.org/10.1158/2159-8290.c.6549335
Autor:
Yin, Wu, Dhruva, Biswas, Ieva, Usaite, Mihaela, Angelova, Stefan, Boeing, Takahiro, Karasaki, Selvaraju, Veeriah, Justyna, Czyzewska-Khan, Cienne, Morton, Magdalene, Joseph, Sonya, Hessey, James, Reading, Andrew, Georgiou, Maise, Al-Bakir, Nicholas, McGranahan, Mariam, Jamal-Hanjani, Allan, Hackshaw, Sergio A, Quezada, Adrian C, Hayday, Phil, Crosbie
Publikováno v:
Nature cancer. 3(6)
Murine tissues harbor signature γδ T cell compartments with profound yet differential impacts on carcinogenesis. Conversely, human tissue-resident γδ cells are less well defined. In the present study, we show that human lung tissues harbor a resi
Autor:
Yin Wu, Dhruva Biswas, Ieva Usaite, Angelova Mihaela, Stefan Boeing, Takahiro Karasaki, Selvaraju Veeriah, Justyna Czyzewska-Khan, James Reading, Andrew Georgiou, Maise Al-Bakir, Nicholas McGranahan, Mariam Jamal-Hanjani, Allan Hackshaw, TRACERx Consortium, Sergio Quezada, Adrian Hayday, Charles Swanton
Publikováno v:
Cancer Research. 82:5636-5636
Murine tissues harbour signature, resident γδ T cell compartments with profound yet differential impacts on carcinogenesis. γδ T cell knockout mice have heightened susceptibility to carcinogenesis. However, it is now clear in the murine setting t
Autor:
Mercedes Duran, Princesca Dorsaint, Julie-Ann Cavallo, Shin-San Michael Su, Dhruva Biswas, Taha Merghoub, Maria Laura Martin, Sreeram Vallabhaneni, Simon N. Powell, Manuel Salto-Tellez, Jedd D. Wolchok, Neil Vasan, Anusha Kalbasi, Nadeem Riaz, Hannah Y Wen, Samuel F. Bakhoum, Jun Li, Benjamin J DiPardo, Jacqueline James, Charles Swanton, Lee S. Gottesdiener, Olivier Elemento, John Kwon, Benjamin Izar, Alexander N. Shoushtari, Rohan Bareja, Hao Wei Li, Matthew G. Hanna, Johannes C. Melms, Ieva Usaite, Kevin Litchfield, Ninjit Dhanota, Matthew P. Humphries, Eileen Parkes, Travis J Hollmann, Roshan K. Sriram, Chantal Pauli, Sarah E Bettigole, Jorge S. Reis-Filho, Peng Li, Walid K. Chatila
Publikováno v:
Li, J, Duran, M A, Dhanota, N, Chatila, W K, Bettigole, S E, Kwon, J, Sriram, R K, Humphries, M P, Salto-Tellez, M, James, J A, Hanna, M G, Melms, J C, Vallabhaneni, S, Litchfield, K, Usaite, I, Biswas, D, Bareja, R, Li, H W, Martin, M L, Dorsaint, P, Cavallo, J-A, Li, P, Pauli, C, Gottesdiener, L, DiPardo, B J, Hollmann, T J, Merghoub, T, Wen, H Y, Reis-Filho, J S, Riaz, N, Su, S-S M, Kalbasi, A, Vasan, N, Powell, S N, Wolchok, J D, Elemento, O, Swanton, C, Shoushtari, A N, Parkes, E E, Izar, B & Bakhoum, S F 2020, ' Metastasis and immune evasion from extracellular cGAMP hydrolysis ', Cancer discovery, vol. Early Online, pp. xx . https://doi.org/10.1158/2159-8290.CD-20-0387
Cancer Discov
Cancer Discov
Cytosolic DNA is characteristic of chromosomally unstable metastatic cancer cells, resulting in constitutive activation of the cGAS–STING innate immune pathway. How tumors co-opt inflammatory signaling while evading immune surveillance remains unkn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa3a80cefbaee3bdab1ee35690a87c04
https://pure.qub.ac.uk/en/publications/metastasis-and-immune-evasion-from-extracellular-cgamp-hydrolysis(6d7c17ea-11d5-406d-8d68-1f1010b32751).html
https://pure.qub.ac.uk/en/publications/metastasis-and-immune-evasion-from-extracellular-cgamp-hydrolysis(6d7c17ea-11d5-406d-8d68-1f1010b32751).html