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Akademický článek

Cannabimimetic N-Stearoylethanolamine as 'Double-Edged Sword' in Anticancer Chemotherapy: Proapoptotic Effect on Tumor Cells and Suppression of Tumor Growth versus Its Bio-Protective Actions in Complex with Polymeric Carrier on General Toxicity of Doxorubicin In Vivo

Autor: Rostyslav Panchuk, Nadiya Skorokhyd, Vira Chumak, Lilya Lehka, Halyna Kosiakova, Tetyana Horid’ko, Iehor Hudz, Nadiya Hula, Anna Riabtseva, Nataliya Mitina, Alexander Zaichenko, Petra Heffeter, Walter Berger, Rostyslav Stoika

Publikováno v: Pharmaceutics, Vol 15, Iss 3, p 835 (2023)

This study reports a dose-dependent pro-apoptotic action of synthetic cannabimimetic N-stearoylethanolamine (NSE) on diverse cancer cell lines, including multidrug-resistant models. No antioxidant or cytoprotective effects of NSE were found when it w

Externí odkaz: https://doaj.org/article/c31b2418cb2841558a46d82502a9b346

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Akademický článek

Cannabimimetic N -Stearoylethanolamine as "Double-Edged Sword" in Anticancer Chemotherapy: Proapoptotic Effect on Tumor Cells and Suppression of Tumor Growth versus Its Bio-Protective Actions in Complex with Polymeric Carrier on General Toxicity of Doxorubicin In Vivo

Autor: Panchuk, Rostyslav^1,2 (AUTHOR), Skorokhyd, Nadiya¹ (AUTHOR), Chumak, Vira¹ (AUTHOR), Lehka, Lilya¹ (AUTHOR), Kosiakova, Halyna³ (AUTHOR), Horid'ko, Tetyana³ (AUTHOR), Hudz, Iehor³ (AUTHOR), Hula, Nadiya³ (AUTHOR), Riabtseva, Anna⁴ (AUTHOR), Mitina, Nataliya⁴ (AUTHOR), Zaichenko, Alexander^4,5 (AUTHOR), Heffeter, Petra² (AUTHOR), Berger, Walter² (AUTHOR), Stoika, Rostyslav¹ (AUTHOR) stoika.rostyslav@gmail.com

Publikováno v: Pharmaceutics. Mar2023, Vol. 15 Issue 3, p835. 29p.

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