Zobrazeno 1 - 10
of 385
pro vyhledávání: '"Iduna, Fichtner"'
Autor:
Franziska Siegel, Hannes Schmidt, Manisha Juneja, Janice Smith, Pia Herrmann, Dennis Kobelt, Kamal Sharma, Iduna Fichtner, Wolfgang Walther, Gunnar Dittmar, Rudolf Volkmer, Fritz G. Rathjen, Peter M. Schlag, Ulrike Stein
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundIdentification of cancer metastasis-relevant molecular networks is desired to provide the basis for understanding and developing intervention strategies. Here we address the role of GIPC1 in the process of MACC1-driven metastasis. MACC1 is
Externí odkaz:
https://doaj.org/article/f7057db6ffbe4927a16349f2de8304f9
Autor:
Joshua Alcaniz, Lars Winkler, Mathias Dahlmann, Michael Becker, Andrea Orthmann, Johannes Haybaeck, Stefanie Krassnig, Christina Skofler, Tobias Kratzsch, Susanne A. Kuhn, Andreas Jödicke, Michael Linnebacher, Iduna Fichtner, Wolfgang Walther, Jens Hoffmann
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Glioblastoma (GBM) heterogeneity, aggressiveness and infiltrative growth drastically limit success of current standard of care drugs and efficacy of various new therapeutic approaches. There is a need for new therapies and models reflecting the compl
Externí odkaz:
https://doaj.org/article/162e4abdb64b415cb7d728a8287cc659
Autor:
Maria Rivera, Iduna Fichtner, Annika Wulf-Goldenberg, Christine Sers, Johannes Merk, Giannino Patone, Keziban M. Alp, Tamara Kanashova, Philipp Mertins, Jens Hoffmann, Ulrike Stein, Wolfgang Walther
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 1, Pp 21-35 (2021)
Patient-derived xenograft (PDX) tumor models represent a valuable platform for identifying new biomarkers and novel targets, to evaluate therapy response and resistance mechanisms. This study aimed at establishment, characterization and therapy testi
Externí odkaz:
https://doaj.org/article/d76f77186ff440aeb1039269f77ac9db
Autor:
Sabrina Grasse, Matthias Lienhard, Steffen Frese, Martin Kerick, Anne Steinbach, Christina Grimm, Michelle Hussong, Jana Rolff, Michael Becker, Felix Dreher, Uwe Schirmer, Stefan Boerno, Anna Ramisch, Gunda Leschber, Bernd Timmermann, Christian Grohé, Heike Lüders, Martin Vingron, Iduna Fichtner, Sebastian Klein, Margarete Odenthal, Reinhard Büttner, Hans Lehrach, Holger Sültmann, Ralf Herwig, Michal R. Schweiger
Publikováno v:
Genome Medicine, Vol 10, Iss 1, Pp 1-16 (2018)
Abstract Background Non-small cell lung cancer (NSCLC) is the most common cause of cancer-related deaths worldwide and is primarily treated with radiation, surgery, and platinum-based drugs like cisplatin and carboplatin. The major challenge in the t
Externí odkaz:
https://doaj.org/article/84b7234bcdf146459a94256898e040dd
Autor:
Shabnam Shalapour, Karl Seeger, Arend von Stackelberg, Javier Prada, Günter Henze, Cornelia Eckert, Iduna Fichtner, Madlen Pfau, Jana Hof, Lorenz Bastian
Purpose: Relapse of disease and subsequent resistance to established therapies remains a major challenge in the treatment of childhood B-cell precursor acute lymphoblastic leukemia (BCP-ALL). New therapeutic options, such as proteasome and histone de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04ab5ca325ca6fb850315241cb2f0b9a
https://doi.org/10.1158/1078-0432.c.6522146.v1
https://doi.org/10.1158/1078-0432.c.6522146.v1
Autor:
Jens Hoffmann, Ulrich Klar, Johannes Merk, Jana Rolff, Michael Becker, Iduna Fichtner, Anette Sommer, Stefanie Hammer
Supplementary Data from Comparative Profiling of the Novel Epothilone, Sagopilone, in Xenografts Derived from Primary Non–Small Cell Lung Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5d514bdb47b2617b472a851613c6b72
https://doi.org/10.1158/1078-0432.22441854.v1
https://doi.org/10.1158/1078-0432.22441854.v1
Autor:
Johannes Merk, Michael Becker, Anette Sommer, Stefanie Hammer, Jens Hoffmann, Richie Soong, Jana Rolff, Iduna Fichtner
Supplementary Data from Establishment of Patient-Derived Non–Small Cell Lung Cancer Xenografts as Models for the Identification of Predictive Biomarkers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab99d4d5ce2b79d691af547cbf58dd89
https://doi.org/10.1158/1078-0432.22439374
https://doi.org/10.1158/1078-0432.22439374
Autor:
Shabnam Shalapour, Karl Seeger, Arend von Stackelberg, Javier Prada, Günter Henze, Cornelia Eckert, Iduna Fichtner, Madlen Pfau, Jana Hof, Lorenz Bastian
PDF file - 47K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::430252ef87217617e489993bc1ddd93e
https://doi.org/10.1158/1078-0432.22451264.v1
https://doi.org/10.1158/1078-0432.22451264.v1
Autor:
Richard Clarkson, Julia Gee, Robert B. Clarke, Maria dM. Vivanco, Marco Piva, Fouad Alchami, Peter Barrett-Lee, Christine Morris, Philippa Young, Ladislav Andera, Iduna Fichtner, Michael Becker, Bruno M. Simões, Angelica Santiago-Gómez, Timothy Robinson, Andreia Silva, Luke Piggott
Figure S1: Endocrine-resistant MCF-7 cells demonstrate sensitivity to TRAIL Figure S2: Endocrine-resistant CSCs demonstrate sensitivity to TRIAL. Figure S3: Primary-derived patient samples. Figure S4: Endocrine-resistant primary and PDX tumour cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e19b7dfd3d8857d41b3de881fc5f24e
https://doi.org/10.1158/1078-0432.22465277
https://doi.org/10.1158/1078-0432.22465277
Autor:
Shabnam Shalapour, Karl Seeger, Arend von Stackelberg, Javier Prada, Günter Henze, Cornelia Eckert, Iduna Fichtner, Madlen Pfau, Jana Hof, Lorenz Bastian
PDF file - 56K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c160e064cf6b0e0a6182c243903370c8
https://doi.org/10.1158/1078-0432.22451273
https://doi.org/10.1158/1078-0432.22451273