Lupus-associated NCF2 variant p.R395W in the NADPH oxidase 2 complex results in a reduced production of reactive oxygen species by myeloid cells

Autor: Song, Zhimin, Yoo, Dae-Goon, Idol, Rachel A., Barbu, Emilia Alina, Jacob, Chaim O., Dinauer, Mary C.

Publikováno v: Frontiers in Lupus. 1

The leukocyte NADPH oxidase 2 (NOX2) generates superoxide, and derivative reactive oxygen species play important roles in both host defense and immunoregulation. The rs13306575 genetic variant, resulting in an Arginine395→Tryptophan (R395W) substit

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https://doi.org/10.3389/flupu.2023.1186641

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Cells depleted for RPS19, a protein associated with Diamond Blackfan Anemia, show defects in 18S ribosomal RNA synthesis and small ribosomal subunit production

Autor: Idol, Rachel A., Robledo, Sara, Du, Hong-Yan, Crimmins, Dan L., Wilson, David B., Ladenson, Jack H., Bessler, Monica, Mason, Philip J.

Publikováno v: In Blood Cells, Molecules and Diseases 2007 39(1):35-43

LysMD3 is a type II membrane protein without an in vivo role in the response to a range of pathogens

Autor: Yokoyama, Christine C, Baldridge, Megan T, Leung, Daisy W, Zhao, Guoyan, Desai, Chandni, Liu, Ta-Chiang, Diaz-Ochoa, Vladimir E, Huynh, Jeremy P, Kimmey, Jacqueline M, Sennott, Erica L, Hole, Camaron R, Idol, Rachel A, Park, Sunmin, Storek, Kelly M, Wang, Caihong, Hwang, Seungmin, Viehmann Milam, Ashley, Chen, Eric, Kerrinnes, Tobias, Starnbach, Michael N, Handley, Scott A, Mysorekar, Indira U, Allen, Paul M, Monack, Denise M, Dinauer, Mary C, Doering, Tamara L, Tsolis, Renee M, Dworkin, Jonathan E, Stallings, Christina L, Amarasinghe, Gaya K, Micchelli, Craig A, Virgin, Herbert W

Publikováno v: The Journal of biological chemistry, vol 293, iss 16
Yokoyama, CC; Baldridge, MT; Leung, DW; Zhao, G; Desai, C; Liu, TC; et al.(2018). LysMD3 is a type II membrane protein without an in vivo role in the response to a range of pathogens. Journal of Biological Chemistry, 293(16), 6022-6038. doi: 10.1074/jbc.RA117.001246. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/7gj113hs

© 2018 by The American Society for Biochemistry and Molecular Biology, Inc. Germline-encoded receptors recognizing common pathogen-associated molecular patterns are a central element of the innate immune system and play an important role in shaping

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::a26ba404e59689d557290a03cb0158e7
https://escholarship.org/uc/item/7gj113hs

Telomerase reverse transcriptase haploinsufficiency and telomere length in individuals with 5p– syndrome.

Autor: Hong-Yan Du¹, Idol, Rachel¹, Robledo, Sara¹, Ivanovich, Jennifer², Ping An³, Londono-Vallejo, Arturo⁴, Wilson, David B.⁵, Mason, Philip J.¹, Bessler, Monica¹ mbessler@im.wustl.edu

Publikováno v: Aging Cell. Oct2007, Vol. 6 Issue 5, p689-697. 9p. 1 Color Photograph, 4 Graphs.