Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Idoia, Busnadiego"'
Autor:
Idoia Busnadiego, Irene A Abela, Pascal M Frey, Daniel A Hofmaenner, Thomas C Scheier, Reto A Schuepbach, Philipp K Buehler, Silvio D Brugger, Benjamin G Hale
Publikováno v:
PLoS Biology, Vol 20, Iss 7, p e3001709 (2022)
Autoantibodies neutralizing the antiviral action of type I interferons (IFNs) have been associated with predisposition to severe Coronavirus Disease 2019 (COVID-19). Here, we screened for such autoantibodies in 103 critically ill COVID-19 patients in
Externí odkaz:
https://doaj.org/article/b3408de1604843568c24aa541f6d426c
Autor:
Sonja Fernbach, Eva E. Spieler, Idoia Busnadiego, Umut Karakus, Anouk Lkharrazi, Silke Stertz, Benjamin G. Hale
Publikováno v:
Cell Reports, Vol 38, Iss 12, Pp 110549- (2022)
Summary: Host interferons (IFNs) powerfully restrict viruses through the action of several hundred IFN-stimulated gene (ISG) products, many of which remain uncharacterized. Here, using RNAi screening, we identify several ISG restriction factors with
Externí odkaz:
https://doaj.org/article/c7fe089cf64945cbabb2229136207bb2
Autor:
Liliana Echavarría-Consuegra, Georgia M Cook, Idoia Busnadiego, Charlotte Lefèvre, Sarah Keep, Katherine Brown, Nicole Doyle, Giulia Dowgier, Krzysztof Franaszek, Nathan A Moore, Stuart G Siddell, Erica Bickerton, Benjamin G Hale, Andrew E Firth, Ian Brierley, Nerea Irigoyen
Publikováno v:
PLoS Pathogens, Vol 17, Iss 6, p e1009644 (2021)
Coronavirus infection induces the unfolded protein response (UPR), a cellular signalling pathway composed of three branches, triggered by unfolded proteins in the endoplasmic reticulum (ER) due to high ER load. We have used RNA sequencing and ribosom
Externí odkaz:
https://doaj.org/article/eaf77300e108401e93e7f0b5b3c8dc13
Autor:
Marie O Pohl, Idoia Busnadiego, Verena Kufner, Irina Glas, Umut Karakus, Stefan Schmutz, Maryam Zaheri, Irene Abela, Alexandra Trkola, Michael Huber, Silke Stertz, Benjamin G Hale
Publikováno v:
PLoS Biology, Vol 19, Iss 3, p e3001006 (2021)
Since entering the human population, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2; the causative agent of Coronavirus Disease 2019 [COVID-19]) has spread worldwide, causing >100 million infections and >2 million deaths. While large-sca
Externí odkaz:
https://doaj.org/article/942eb63eba2e43ccbc2ad9759b98db2c
Autor:
Idoia Busnadiego, Sonja Fernbach, Marie O. Pohl, Umut Karakus, Michael Huber, Alexandra Trkola, Silke Stertz, Benjamin G. Hale
Publikováno v:
mBio, Vol 11, Iss 5 (2020)
ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of coronavirus disease 2019 (COVID-19), is a recently emerged respiratory coronavirus that has infected >23 million people worldwide with >800,000 deaths. Few COVID-19 t
Externí odkaz:
https://doaj.org/article/fa5798cc3bce4c0196b825fcd06ded1e
Autor:
Idoia Busnadiego, Irene A. Abela, Pascal M. Frey, Daniel A. Hofmaenner, Thomas C. Scheier, Reto A. Schuepbach, Philipp K. Buehler, Silvio D. Brugger, Benjamin G. Hale
Autoantibodies neutralizing the antiviral action of type I interferons (IFNs) have been associated with pre-disposition to severe COVID-19. Here, we screened for such autoantibodies in 103 critically-ill COVID-19 patients in a tertiary intensive care
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd65d69c0361b5c295a702025937ce00
https://doi.org/10.1101/2022.03.19.22272532
https://doi.org/10.1101/2022.03.19.22272532
Autor:
Sonja, Fernbach, Eva E, Spieler, Idoia, Busnadiego, Umut, Karakus, Anouk, Lkharrazi, Silke, Stertz, Benjamin G, Hale
Publikováno v:
Cell reports. 38(12)
Host interferons (IFNs) powerfully restrict viruses through the action of several hundred IFN-stimulated gene (ISG) products, many of which remain uncharacterized. Here, using RNAi screening, we identify several ISG restriction factors with previousl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::29ae12d6d80e17a111e4f14a2c128f48
https://pubmed.ncbi.nlm.nih.gov/35320721
https://pubmed.ncbi.nlm.nih.gov/35320721
Autor:
Akram Rahimi, Idoia Busnadiego, Matteo Gasbarri, Marie O. Pohl, Antonius Armanious, Caroline Tapparel, Francesco Stellacci, Mohammad Peydayesh, Stephan Handschin, Benjamin G. Hale, Raffaele Mezzenga, Sreenath Bolisetty, Christian Gübeli, Ravi B. Anjanappa, Silke Stertz, Archana Palika, Antonella Rossi, Chiara Medaglia
Publikováno v:
Nature Nanotechnology, 16
Nature Nanotechnology, Vol. 16, No 8 (2021) pp. 918-925
Nature Nanotechnology, Vol. 16, No 8 (2021) pp. 918-925
Minimizing the spread of viruses in the environment is the first defense line when fighting outbreaks and pandemics, but the current SARS-CoV-2 pandemic demonstrates how difficult this is on global scale, particularly in a sustainable and environment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::681dcd0272c77ef73a4437d87b71c009
https://hdl.handle.net/20.500.11850/488402
https://hdl.handle.net/20.500.11850/488402
Autor:
Nathan A. Moore, Giulia Dowgier, Liliana Echavarría-Consuegra, Katherine A. Brown, Ian Brierley, Andrew E. Firth, Nicole Doyle, Charlotte Lefèvre, Sarah Keep, Georgia M. Cook, Nerea Irigoyen, Erica Bickerton, Stuart G. Siddell, Krzysztof Franaszek, Benjamin G. Hale, Idoia Busnadiego
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 6, p e1009644 (2021)
PLoS Pathogens, Vol 17, Iss 6, p e1009644 (2021)
Coronavirus infection induces the unfolded protein response (UPR), a cellular signalling pathway composed of three branches, triggered by unfolded proteins in the endoplasmic reticulum (ER) due to high ER load. We have used RNA sequencing and ribosom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e359e70de9d2cee48f0d6f7b570ad45a
http://europepmc.org/articles/PMC8211288
http://europepmc.org/articles/PMC8211288
Autor:
Annika Hunziker, Silke Stertz, Amedeo Caflisch, Idoia Busnadiego, Sonja Fernbach, Elena V. Moroz-Omori, L. Wiedmer, Marie O. Pohl, Benjamin G. Hale, Francesco Marrafino, Irina Glas
Publikováno v:
The Journal of General Virology
Rapid repurposing of existing drugs as new therapeutics for COVID-19 has been an important strategy in the management of disease severity during the ongoing SARS-CoV-2 pandemic. Here, we screened by high-throughput docking 6,000 compounds within the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d5c071da13c1f779c14e67d8e57e1ee
https://doi.org/10.1101/2021.03.19.435806
https://doi.org/10.1101/2021.03.19.435806