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pro vyhledávání: '"Idiopathic Pulmonary Fibrosis/genetics/metabolism/pathology"'
Autor:
Cécile Guichard, Botond Banfi, Karl-Heinz Krause, Olivier Basset, Olivier Preynat-Seauve, Boris Hinz, Jean-Claude Pache, Constance Barazzone-Argiroffo, Christine Deffert, Jack L. Arbiser, Stephanie Carnesecchi, Yves Donati
Publikováno v:
Antioxidants & redox signaling
Antioxidants and Redox Signaling, Vol. 15, No 3 (2011) pp. 607-19
Antioxidants and Redox Signaling, Vol. 15, No 3 (2011) pp. 607-19
The pathogenesis of pulmonary fibrosis is linked to oxidative stress, possibly generated by the reactive oxygen species (ROS) generating NADPH oxidase NOX4. Epithelial cell death is a crucial early step in the development of the disease, followed onl