Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Idan Cohen"'
Autor:
Mathumathi Krishnamohan, Irena Kaplanov, Sapir Maudi-Boker, Muhammad Yousef, Noy Machluf-Katz, Idan Cohen, Moshe Elkabets, Jaison Titus, Marina Bersudsky, Ron N. Apte, Elena Voronov, Alex Braiman
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 7, p 3950 (2024)
IL-1α is a dual function cytokine that affects inflammatory and immune responses and plays a pivotal role in cancer. The effects of intracellular IL-1α on the development of triple negative breast cancer (TNBC) in mice were assessed using the CRISP
Externí odkaz:
https://doaj.org/article/4822f21ceef94b0493f03454122b3d75
Autor:
Joshua Aviram, Gil M. Lewitus, Yelena Vysotski, Mahmoud Abu Amna, Anton Ouryvaev, Shiri Procaccia, Idan Cohen, Anca Leibovici, Luiza Akria, Dimitry Goncharov, Neomi Mativ, Avia Kauffman, Ayelet Shai, Gil Bar-Sela, David Meiri
Publikováno v:
Frontiers in Pain Research, Vol 3 (2022)
The use of medical cannabis (MC) to treat cancer-related symptoms is rising. However, there is a lack of long-term trials to assess the benefits and safety of MC treatment in this population. In this work, we followed up prospectively and longitudina
Externí odkaz:
https://doaj.org/article/0e62212239e74aa79ad8acd7045b712e
Autor:
Barak Rotblat, Andreas Mock, Jerome Fayette, Limor Cohen, Idan Cohen, Elena Voronov, Jebrane Bouaoud, Lucas Michon, Pierre Saintigny, Luc G T Morris, Manu Prasad, Jonathan Zorea, Sankar Jagadeeshan, Avital B Shnerb, Sooraj Mathukkada, Ofra Novoplansky, Mai Badarni, Ksenia M Yegodayev, Sapir Tzadok, Libor Brezina, Andy Karabajakian, Tomer Cooks, Irit Allon, Orr Dimitstein, Benzion Joshua, Dexin Kong, Maurizio Scaltriti, Yaron Carmi, Cristina Conde-Lopez, Jochen Hess, Ina Kurth, Moshe Elkabets
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 3 (2022)
Background Although the mitogen-activated protein kinases (MAPK) pathway is hyperactive in head and neck cancer (HNC), inhibition of MEK1/2 in HNC patients has not shown clinically meaningful activity. Therefore, we aimed to characterize the effect o
Externí odkaz:
https://doaj.org/article/e52b0f83da384bc987314eeb1cc6f2e4
Publikováno v:
JPhys Energy, Vol 5, Iss 3, p 035011 (2023)
Organic ligands play a crucial role in the properties and functionality of nanostructures. Functional ligands are an interesting research direction that can be utilized to influence the properties and functionality of nanoparticles (NPs). In this wor
Externí odkaz:
https://doaj.org/article/bd7f6324526c4120ba5bf602b726e34f
Publikováno v:
Cells, Vol 11, Iss 15, p 2404 (2022)
Epigenetic regulation plays an essential role in driving precise transcriptional programs during development and homeostasis. Among epigenetic mechanisms, histone mono-ubiquitination has emerged as an important post-transcriptional modification. Two
Externí odkaz:
https://doaj.org/article/83b968ab2f5e44209a67549a84cfeeb1
Publikováno v:
Oncology and Therapy, Vol 6, Iss 2, Pp 109-127 (2018)
Abstract Interleukin-1 (IL-1) has long been known to be a key mediator of immunity and inflammation. Its dysregulation has been implicated in recent years in tumorigenesis and tumor progression, and its upregulation is thought to be associated with m
Externí odkaz:
https://doaj.org/article/3db108c31a0e49609fb21e93341e1c6e
Publikováno v:
Pharmaceutics, Vol 14, Iss 2, p 389 (2022)
Cannabis, as a natural medicinal remedy, has long been used for palliative treatment to alleviate the side effects caused by diseases. Cannabis-based products isolated from plant extracts exhibit potent immunoregulatory properties, reducing chronic i
Externí odkaz:
https://doaj.org/article/ee30ad5e16454736ad949e300b605963
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Diabetes mellitus is linked with metabolic stress that induces cellular damage and can provoke renal inflammation and fibrotic responses that eventually lead to chronic kidney disease. Because the inflammasome, interleukin 1 (IL-1), IL-1α/IL-β, and
Externí odkaz:
https://doaj.org/article/2d9e5fe09e9a4417b6372337b6238b62
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0240994 (2020)
Extracellular vesicles (EVs) are subcellular membrane blebs that include exosomes and microparticles, which represent a potential source for cancer biomarker discovery. We assess EVs characteristics as a tool to evaluate the endothelial and anti-tumo
Externí odkaz:
https://doaj.org/article/54edb4aeb23141e8900e82e5bd196a5c
Autor:
Minh Binh Nguyen, Idan Cohen, Vinod Kumar, Zijian Xu, Carmit Bar, Katherine L. Dauber-Decker, Pai-Chi Tsai, Pauline Marangoni, Ophir D. Klein, Ya-Chieh Hsu, Ting Chen, Marja L. Mikkola, Elena Ezhkova
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Merkel cells are mechanoreceptors located in the epidermis whose developmental origin is unclear. Here the authors show that Merkel cells originate from SOX9 positive cells inside hair follicles and that FGFR2-mediated epithelial signalling is requir
Externí odkaz:
https://doaj.org/article/f06a4283856d4067bfcbe380ad9407b0