Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Idalia M. Yabe"'
Autor:
Sandeep K. Srivastava, Lauren L. Truitt, Chuanfeng Wu, Adam Glaser, Daniel J. Nolan, Michael Ginsberg, Diego A. Espinoza, Samson Koelle, Idalia M. Yabe, Kyung-Rok Yu, Sogun Hong, Stephanie Sellers, Allen Krouse, Aylin Bonifacino, Mark Metzger, Pradeep K. Dagur, Robert E. Donahue, Cynthia E. Dunbar, Sandhya R. Panch
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 20, Iss , Pp 703-715 (2021)
Ex vivo hematopoietic stem and progenitor cell (HSPC) expansion platforms are under active development, designed to increase HSPC numbers and thus engraftment ability of allogeneic cord blood grafts or autologous HSPCs for gene therapies. Murine and
Externí odkaz:
https://doaj.org/article/f752637eb89a49feb1dc785c3084f549
Autor:
Idalia M. Yabe, Lauren L. Truitt, Diego A. Espinoza, Chuanfeng Wu, Samson Koelle, Sandhya Panch, Marcus A.F. Corat, Thomas Winkler, Kyung-Rok Yu, So Gun Hong, Aylin Bonifacino, Allen Krouse, Mark Metzger, Robert E. Donahue, Cynthia E. Dunbar
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 11, Iss , Pp 143-154 (2018)
Gene therapies using integrating retrovirus vectors to modify hematopoietic stem and progenitor cells have shown great promise for the treatment of immune system and hematologic diseases. However, activation of proto-oncogenes via insertional mutagen
Externí odkaz:
https://doaj.org/article/af788885a60b4f71bbaeb35e5dd381a5
Autor:
Samson J. Koelle, Idalia M. Yabe, Michael Ginsberg, Diego A. Espinoza, Chuanfeng Wu, Kyung-Rok Yu, Adam Glaser, So Gun Hong, Lauren L. Truitt, Mark E. Metzger, Allen E. Krouse, Sandhya R. Panch, Cynthia E. Dunbar, Stephanie Sellers, Pradeep K. Dagur, Sandeep Kumar Srivastava, Robert E. Donahue, Aylin C. Bonifacino, Daniel J. Nolan
Publikováno v:
Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 20, Iss, Pp 703-715 (2021)
Molecular Therapy: Methods & Clinical Development, Vol 20, Iss, Pp 703-715 (2021)
Ex vivo hematopoietic stem and progenitor cell (HSPC) expansion platforms are under active development, designed to increase HSPC numbers and thus engraftment ability of allogeneic cord blood grafts or autologous HSPCs for gene therapies. Murine and
Autor:
Katherine R. Calvo, Idalia M. Yabe, Kristin J Hope, Chuanfeng Wu, Xing Fan, Xiaolin Wu, Rong Lu, Aylin C. Bonifacino, Lauren L. Truitt, Stefan Cordes, Di Yang, Robert E. Donahue, Diego A. Espinoza, Cynthia E. Dunbar, So Gun Hong, Suk See DeRavin, Allen E. Krouse, Mark E. Metzger, John F. Tisdale, Harry L. Malech, Selami Demirci, Naoya Uchida
Publikováno v:
Mol Ther
Lentiviral vectors (LVs) are used for delivery of genes into hematopoietic stem and progenitor cells (HSPCs) in clinical trials worldwide. LVs, in contrast to retroviral vectors, are not associated with insertion site-associated malignant clonal expa
Autor:
Robert E. Donahue, So Gun Hong, Allen E. Krouse, Lauren L. Truitt, Idalia M. Yabe, Sandhya R. Panch, Kyung-Rok Yu, Chuanfeng Wu, Samson J. Koelle, Rong Lu, Aylin C. Bonifacino, Cynthia E. Dunbar, Xing Fan, Diego A. Espinoza, Tae-Hoon Shin, Mark E. Metzger, Shirley Chen
Publikováno v:
Blood. 131:1195-1205
Age-associated changes in hematopoietic stem and progenitor cells (HSPCs) have been carefully documented in mouse models but poorly characterized in primates and humans. To investigate clinically relevant aspects of hematopoietic aging, we compared t
Autor:
Kristin J Hope, Xing Fan, Katherine R. Calvo, Selami Demirci, Xiaolin Wu, Rong Lu, Lauren L. Truitt, Aylin C. Bonifacino, Cynthia E. Dunbar, Naoya Uchida, Mark E. Metzger, Robert E. Donahue, Idalia M. Yabe, So Gun Hong, Allen E. Krouse, Stefan Cordes, Di Yang, Suk See DeRavin, Diego A. Espinoza, John F. Tisdale, Harry L. Malech, Chuanfeng Wu
Lentiviral vectors (LV) have been used for the delivery of genes into hematopoietic stem and progenitor cells (HSPC) in clinical trials worldwide. LV, in contrast to retroviral vectors, have not been associated with insertion site-associated malignan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5dc73097700aeec7ab71b9a87b12d552
https://doi.org/10.1101/525691
https://doi.org/10.1101/525691
Publikováno v:
Clinical and Vaccine Immunology. 23:638-647
Earlier studies aimed at defining protective immunity induced by Mycobacterium bovis BCG immunization have largely focused on the induction of antituberculosis CD4 + and CD8 + T cell responses. Here we describe a vaccine consisting of a BCGΔ mmaA4 d
Autor:
Paola De Luca, Jesse Quintero, Idalia M. Yabe, Yun Ge, Jung S. Byun, William D. Figg, Quentin Li, Geraldine Gueron, Adriana De Siervi, Sara G. Sadiq-Ali, Cynthia M. Haggerty, Kevin Gardner
Publikováno v:
Molecular Pharmacology. 74:872-883
2-(2,4-Difluoro-phenyl)-4,5,6,7-tetrafluoro-1H-isoindole-1,3(2H)-dione (CPS49) is a member of a recently identified class of redox-reactive thalidomide analogs that show selective killing of leukemic cells by increasing intracellular reactive oxygen
Autor:
Amy Yang, Kristopher Kolibab, Idalia M. Yabe, Sheldon L. Morris, Sherry L. Kurtz, Steven C. Derrick, Brynn Hollingsworth
Publikováno v:
Vaccine. 31(41)
With tuberculosis continuing to be a major cause of global morbidity and mortality, a new vaccine is urgently needed. Tuberculosis subunit vaccines have been shown to induce robust immune responses in humans and are a potentially safer alternative to
Autor:
Stephanie Sellers, So Gun Hong, Allen E. Krouse, Cynthia E. Dunbar, Robert E. Donahue, Aylin C. Bonifacino, Diego A. Espinoza, Sandhya R. Panch, Idalia M. Yabe, Chuanfeng Wu
Publikováno v:
Molecular Therapy. 24:S209
The development of ex-vivo HSPC expansion techniques is particulary relevant for improving cord blood transplantation and gene therapy. Despite successful long-term, multilineage reconstitution of expanded human cord blood HSPC in immunodeficient mic