Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Ida Rapa"'
Autor:
Antonina Germano, Laura Saba, Silvia De Francia, Ida Rapa, Paola Perotti, Alfredo Berruti, Marco Volante, Massimo Terzolo
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0196931 (2018)
Mitotane is the reference drug for adrenocortical carcinoma (ACC) and the metabolic activation of the drug is considered as essential for its activity. The aim of this study was to assess the role of CYP11B1 on mitotane action and metabolism in H295R
Externí odkaz:
https://doaj.org/article/639b6df1e4d74c81b4a767a4a1e89076
Autor:
Heike Allgayer, Mauro Papotti, Giorgio V. Scagliotti, Ida Rapa, Regalla Kumarswamy, Giridhar Mudduluru, Paolo Ceppi
The development of metastases is the main reason for cancer-related death in non–small cell lung cancer (NSCLC). The initiation of metastasis involves an increase in cell motility mediated by the loss of cell-cell adhesion caused by E-cadherin repr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ab37cb1ca17f67b018edd987965dc27
https://doi.org/10.1158/1541-7786.c.6542286.v1
https://doi.org/10.1158/1541-7786.c.6542286.v1
Autor:
Heike Allgayer, Mauro Papotti, Giorgio V. Scagliotti, Ida Rapa, Regalla Kumarswamy, Giridhar Mudduluru, Paolo Ceppi
Supplementary Figures S1-S4.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ab9d2c653ff4f740315acde65b28c17
https://doi.org/10.1158/1541-7786.22519095.v1
https://doi.org/10.1158/1541-7786.22519095.v1
Autor:
Paolo Ceppi, Thomas Brabletz, Florian R. Greten, Marco Volante, Ozgur Sahin, Peter J. Oefner, Dimitrios Mougiakakos, Suhail Ahmed Kabeer Rasheed, Arif B. Ekici, Maximilian J. Waldner, Katja Dettmer-Wilde, Ida Rapa, Fulvia Ferrazzi, Angela M. Krebs, Özge Saatci, Umar Raza, Bianca Menchicchi, Martin Böttcher, Francesca Napoli, Maria Eleni Vazakidou, Aarif Siddiqui, Annemarie Schwab
SUPPLEMENTARY FIGURE 1 Correlation of VIM/CDH1 ratios in different datasets. The list of 35 genes significantly correlated with EMT. Lack of correlation between AKR1B10 mRNA levels and EMT. SUPPLEMENTARY FIGURE 2 AKR1B1 levels are modulated by ZEB1,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::563959ca410828b98abfb6fe87c6fbed
https://doi.org/10.1158/0008-5472.22420748.v1
https://doi.org/10.1158/0008-5472.22420748.v1
Autor:
Alfredo Berruti, Mauro Papotti, Bruno Allolio, Giorgio Scagliotti, Paola Sperone, Fulvia Daffara, Silviu Sbiera, Antonina Germano, Ida Rapa, Martin Fassnacht, Massimo Terzolo, Marco Volante
PDF file, 43KB.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b03226b8f174a87549baa60f4f0ae3b
https://doi.org/10.1158/1078-0432.22444817.v1
https://doi.org/10.1158/1078-0432.22444817.v1
Autor:
Paolo Ceppi, Thomas Brabletz, Florian R. Greten, Marco Volante, Ozgur Sahin, Peter J. Oefner, Dimitrios Mougiakakos, Suhail Ahmed Kabeer Rasheed, Arif B. Ekici, Maximilian J. Waldner, Katja Dettmer-Wilde, Ida Rapa, Fulvia Ferrazzi, Angela M. Krebs, Özge Saatci, Umar Raza, Bianca Menchicchi, Martin Böttcher, Francesca Napoli, Maria Eleni Vazakidou, Aarif Siddiqui, Annemarie Schwab
List of differentially expressed genes in all analyzed datasets
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86e2addf3d6c8de2c1035abed96f614b
https://doi.org/10.1158/0008-5472.22420745
https://doi.org/10.1158/0008-5472.22420745
Autor:
Paolo Ceppi, Thomas Brabletz, Florian R. Greten, Marco Volante, Ozgur Sahin, Peter J. Oefner, Dimitrios Mougiakakos, Suhail Ahmed Kabeer Rasheed, Arif B. Ekici, Maximilian J. Waldner, Katja Dettmer-Wilde, Ida Rapa, Fulvia Ferrazzi, Angela M. Krebs, Özge Saatci, Umar Raza, Bianca Menchicchi, Martin Böttcher, Francesca Napoli, Maria Eleni Vazakidou, Aarif Siddiqui, Annemarie Schwab
Cancer cells alter their metabolism to support their malignant properties. In this study, we report that the glucose-transforming polyol pathway (PP) gene aldo-keto-reductase-1-member-B1 (AKR1B1) strongly correlates with epithelial-to-mesenchymal tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73301a0dc4a2223708c9bc42b10a454f
https://doi.org/10.1158/0008-5472.c.6510746
https://doi.org/10.1158/0008-5472.c.6510746
Autor:
Alfredo Berruti, Mauro Papotti, Bruno Allolio, Giorgio Scagliotti, Paola Sperone, Fulvia Daffara, Silviu Sbiera, Antonina Germano, Ida Rapa, Martin Fassnacht, Massimo Terzolo, Marco Volante
Purpose: Mitotane is the most broadly used systemic therapy for adrenocortical carcinoma (ACC), but its mechanism of action and possible predictors of treatment response are currently poorly defined. Our aim was to evaluate the gene expression of rib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b0b594bbe064ec46fa370711d887d2d
https://doi.org/10.1158/1078-0432.c.6520301
https://doi.org/10.1158/1078-0432.c.6520301
Autor:
Daniel Moya-Rull, Annunziata Gloghini, Andrea Sartore-Bianchi, Salvatore Siena, Ivana Sarotto, Simonetta Guarrera, Sara Erika Bellomo, Stefania Manenti, Emanuele Rausa, Laura D'Errico, Ida Rapa, Sabrina Rizzolio, Uberto Fumagalli, Rossella Reddavid, Claudia Castelli, Caterina Marchiò, Carla Baronchelli, Tania Capeloa, Federica Morano, Simona Corso, Michele Sacco, Dario Ribero, Stefano De Pascale, Gian Luca Baiocchi, Federica Tosi, Maria Apicella, Salvatore Ribisi, Paola Cassoni, Maurizio Degiuli, Sarah Molfino, Giovanni Sgroi, Silvia Marsoni, Michele Prisciandaro, Stefania Durando, Cristina Migliore, Annalisa Petrelli, Antonino Sottile, Filippo Pietrantonio, Silvia Giordano, Alessandra Raimondi, Anna Sapino, Maria Bencivenga, Stefano Ughetto
Publikováno v:
Gastric Cancer. 24:897-912
Trastuzumab is the only approved targeted therapy in patients with HER2-amplified metastatic gastric cancer (GC). Regrettably, in clinical practice, only a fraction of them achieves long-term benefit from trastuzumab-based upfront strategy. To advanc
Autor:
Jasna Metovic, Anna La Salvia, Ida Rapa, Francesca Napoli, Nadia Birocco, Maria Pia Bizzi, Rocio Garcia-Carbonero, Libero Ciuffreda, Giorgio Scagliotti, Mauro Papotti, Marco Volante
Publikováno v:
Endocrine pathology. 33(3)
Extra-pulmonary neuroendocrine carcinomas (EPNEC) represent a group of rare and heterogenous neoplasms with adverse clinical outcome. Their molecular profile is largely unexplored. Our aim was to investigate if the major transcriptional drivers recen