New Insights into the Occurrence of Matrix Metalloproteases -2 and -9 in a Cohort of Breast Cancer Patients and Proteomic Correlations

Autor: Gianluca Di Cara, Maria Rita Marabeti, Rosa Musso, Ignazio Riili, Patrizia Cancemi, Ida Pucci Minafra

Publikováno v: Cells, Vol 7, Iss 8, p 89 (2018)

Matrix metalloproteases (MMPs) are a family of well-known enzymes which operate prevalently in the extracellular domain, where they fulfil the function of remodeling the extracellular matrix (ECM). Within the 26 family members, encoded by 24 genes in

Externí odkaz: https://doaj.org/article/d2aecd78e46341f6aa0a491feee83fba

Prognostic and Functional Significant of Heat Shock Proteins (HSPs) in Breast Cancer Unveiled by Multi-Omics Approaches

Autor: Miriam Buttacavoli, Gianluca Di Cara, Cesare D’Amico, Fabiana Geraci, Ida Pucci-Minafra, Salvatore Feo, Patrizia Cancemi

Publikováno v: Biology, Vol 10, Iss 3, p 247 (2021)

Heat shock proteins (HSPs) are a well-characterized molecular chaperones protein family, classified into six major families, according to their molecular size. A wide range of tumors have been shown to express atypical levels of one or more HSPs, sug

Externí odkaz: https://doaj.org/article/0ea2ea80a5f9419cb782d97bd3631bd7

Integrated multi-omics investigations of metalloproteinases in colon cancer: Focus on MMP2 and MMP9

Autor: Ida Pucci-Minafra, Gianluca Di Cara, Salvatore Feo, Patrizia Cancemi, Miriam Buttacavoli, Elena Roz

Publikováno v: International Journal of Molecular Sciences
Volume 22
Issue 22
International Journal of Molecular Sciences, Vol 22, Iss 12389, p 12389 (2021)

Colorectal cancer (CRC) develops by genetic and epigenetic alterations. However, the molecular mechanisms underlying metastatic dissemination remain unclear and could benefit from multi-omics investigations of specific protein families. Matrix metall

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64d5c84be7e7f162b9bfce128884badd
http://hdl.handle.net/10447/528654

Proteomic Profiling of Colon Cancer Tissues: Discovery of New Candidate Biomarkers

Autor: Elena Roz, Salvatore Feo, Miriam Buttacavoli, Patrizia Cancemi, Nadia Ninfa Albanese, Ida Pucci-Minafra

Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 3096, p 3096 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 9

Colon cancer is an aggressive tumor form with a poor prognosis. This study reports a comparative proteomic analysis performed by using two-dimensional differential in-gel electrophoresis (2D-DIGE) between 26 pooled colon cancer surgical tissues and a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e7554b448fedf572992950805f8d866
https://www.mdpi.com/1422-0067/21/9/3096

A multiomics analysis of S100 protein family in breast cancer

Autor: Nadia Ninfa Albanese, Patrizia Cancemi, Gianluca Di Cara, Ida Pucci-Minafra, Miriam Buttacavoli, Salvatore Feo, Serena Bivona

Publikováno v: Oncotarget

The S100 gene family is the largest subfamily of calcium binding proteins of EF-hand type, expressed in tissue and cell-specific manner, acting both as intracellular regulators and extracellular mediators. There is a growing interest in the S100 prot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ea6596b59cd0526c8bf468c7bad8a76
http://hdl.handle.net/10447/293621