Zobrazeno 1 - 10 of 24 pro vyhledávání: '"Ida Karin Nordgren"'
1
Akademický článek
Evaluation of Critical Quality Attributes of a Pentavalent (A, C, Y, W, X) Meningococcal Conjugate Vaccine for Global Use
Autor: Barbara Bolgiano, Eilís Moran, Nicola J. Beresford, Fang Gao, Rory Care, Trusha Desai, Ida Karin Nordgren, Timothy R. Rudd, Ian M. Feavers, Prashant Bore, Sushil Patni, Vinay Gavade, Asha Mallya, Sameer Kale, Pankaj Sharma, Sunil K. Goel, Sunil Gairola, Suhas Hattarki, Nikhil Avalaskar, Annamraju D. Sarma, Marc LaForce, Neil Ravenscroft, Lakshmi Khandke, Mark R. Alderson, Rajeev M. Dhere, Sambhaji S. Pisal
Publikováno v: Pathogens, Vol 10, Iss 8, p 928 (2021)
Towards achieving the goal of eliminating epidemic outbreaks of meningococcal disease in the African meningitis belt, a pentavalent glycoconjugate vaccine (NmCV-5) has been developed to protect against Neisseria meningitidis serogroups A, C, Y, W and
Externí odkaz: https://doaj.org/article/ed955ddea0f7409d8a5231da50c31f7e
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2
Akademický článek
Development of a Monocyte Activation Test as an Alternative to the Rabbit Pyrogen Test for Mono- and Multi-Component Shigella GMMA-Based Vaccines
Autor: Danielle Carson, Sophie Myhill, Elena Palmieri, Francesca Necchi, Sjoerd Rijpkema, Francesca Micoli, Ida Karin Nordgren, Omar Rossi, Caroline Vipond
Publikováno v: Microorganisms, Vol 9, Iss 7, p 1375 (2021)
Generalised modules for membrane antigens (GMMA)-based vaccines comprise the outer membrane from genetically modified Gram-negative bacteria containing membrane proteins, phospholipids and lipopolysaccharides. Some lipoproteins and lipopolysaccharide
Externí odkaz: https://doaj.org/article/9c99c3bce33e4c9197a514716950ba69
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3
Development of a Monocyte Activation Test as an Alternative to the Rabbit Pyrogen Test for Mono- and Multi-Component Shigella GMMA-Based Vaccines
Autor: Omar Rossi, Danielle Carson, Elena Palmieri, Caroline Vipond, Ida Karin Nordgren, Francesca Micoli, Sjoerd Rijpkema, Francesca Necchi, Sophie Myhill
Publikováno v: Microorganisms, Vol 9, Iss 1375, p 1375 (2021)
Microorganisms
Volume 9
Issue 7
Generalised modules for membrane antigens (GMMA)-based vaccines comprise the outer membrane from genetically modified Gram-negative bacteria containing membrane proteins, phospholipids and lipopolysaccharides. Some lipoproteins and lipopolysaccharide
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4b5cb066d2aec96a9c2c8b9fd300184
https://www.mdpi.com/2076-2607/9/7/1375
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5
Understanding the reactogenicity of 4CMenB vaccine: Comparison of a novel and conventional method of assessing post-immunisation fever and correlation with pre-release in vitro pyrogen testing
Autor: Nick Andrews, Marta Valente Pinto, Jo Southern, Emma Plested, Elizabeth Miller, Kimberly Davis, Ida Karin Nordgren, Caroline Vipond, Matthew D. Snape, David Goldblatt, Ray Borrow
Publikováno v: Vaccine. 38(49)
BACKGROUND Better understanding of vaccine reactogenicity is crucial given its potential impact upon vaccine safety and acceptance. Here we report a comparison between conventional and novel (continuous) methods of monitoring temperature and evaluate
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fca94515e0216f6d8ebbe0a1202f4717
https://pubmed.ncbi.nlm.nih.gov/33109390
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6
Evaluation of the monocyte activation test for the safety testing of meningococcal B vaccine Bexsero: A collaborative study
Autor: Jason Hockley, Trusha Desai, Lucy Studholme, Janet Sutherland, Rory Care, Caroline Vipond, Ida Karin Nordgren
Publikováno v: Vaccine. 37(29)
The aim of this collaborative study was to evaluate the robustness of the monocyte activation test (MAT) for quantifying the pyrogenic content in the outer membrane vesicle (OMV)-containing vaccine Bexsero: the first meningococcal B vaccine to be lic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd6db81e3cf217021da013235c04a218
https://pubmed.ncbi.nlm.nih.gov/31202504
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7
A Cyclic Peptide Inhibitor of HIF-1 Heterodimerization That Inhibits Hypoxia Signaling in Cancer Cells
Autor: Elena Miranda, Ali Tavassoli, Paul A. Townsend, Keith R. Fox, Suzanne A. Eccles, William Court, Franciane Hoakwie, F. Cuda, Abigail L. Male, Ida Karin Nordgren, Graham Packham, Charlotte E. Lawrence
Publikováno v: Journal of the American Chemical Society
Hypoxia inducible factor-1 (HIF-1) is a heterodimeric transcription factor that acts as the master regulator of cellular response to reduced oxygen levels, thus playing a key role in the adaptation, survival and progression of tumors. Here we report
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adff389052d2ab392dcfd8359c42daed
https://doi.org/10.1021/ja402993u
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8
Leukoreduction system chambers provide a valuable source of functional monocytes for the monocyte activation test by comparison with internationally validated methods
Autor: Ida Karin Nordgren
Publikováno v: Journal of immunological methods. 428
Despite being added to the European Pharmacopoeia in 2010 and strongly supported by the European directive enforcing the "3R's" - Replace, Reduce and Refine, uptake of the monocyte activation test (MAT) in preference over the rabbit pyrogen test for
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78a5a9445a809466327099f20b2d6309
https://pubmed.ncbi.nlm.nih.gov/26678159
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