Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Ida H van der Meulen-Muileman"'
Autor:
Tereza Brachtlova, Jing Li, Ida H. van der Meulen-Muileman, Femke Sluiter, Willem von Meijenfeldt, Isabella Witte, Sanne Massaar, Ruben van den Oever, Jeroen de Vrij, Victor W. van Beusechem
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 12, p 6551 (2024)
Oncolytic adenoviruses are in development as immunotherapeutic agents for solid tumors. Their efficacy is in part dependent on their ability to replicate in tumors. It is, however, difficult to obtain evidence for intratumoral oncolytic adenovirus re
Externí odkaz:
https://doaj.org/article/a61d66c45fa54be9819df189af22b270
Autor:
Jing Li, Tereza Brachtlova, Ida H. van der Meulen-Muileman, Stijn Kleerebezem, Chang Liu, Peiyu Li, Victor W. van Beusechem
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 20, p 15425 (2023)
To promote the preclinical development of new treatments for non-small cell lung cancer (NSCLC), we established NSCLC xenograft tumor assays on the chorioallantoic membrane (CAM) of chicken embryos. Five NSCLC cell lines were compared for tumor take
Externí odkaz:
https://doaj.org/article/af40a34c5e784b5bbd1a6cfeb08ea921
Autor:
Christie Vermeulen, Tereza Brachtlova, Nikki Tol, Ida H. van der Meulen-Muileman, Jasmina Hodzic, Henri J. van de Vrugt, Victor W. van Beusechem
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 15430 (2022)
Oncolytic adenoviruses are promising new anticancer agents. To realize their full anticancer potential, they are being engineered to express therapeutic payloads. Tumor suppressor p53 function contributes to oncolytic adenovirus activity. Many cancer
Externí odkaz:
https://doaj.org/article/98640cbf198a4e4e8fd57c260d8ef958
Autor:
Emanuela Felley-Bosco, Victor W. van Beusechem, Lorenza Penengo, Rolf A. Stahel, Walter Weder, Egbert F. Smit, Kathrin Oehl, Martin Wipplinger, Renee X. de Menezes, Ida H. van der Meulen-Muileman, Maxime Blijlevens, Manuel Ronner, Vasundhara Rao, Saskja Bühler, Agata Okonska
Supplementary Fig. S1: Characterization of the model used for whole genome silencing, individual screen lethality scores and list of candidate genes with differential lethality scores ; Supplementary Fig. S2: Validation of the RRM1 and RRM2 knockdown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::605ff950fc1c5dce74ce496371b31574
https://doi.org/10.1158/1535-7163.22505877.v1
https://doi.org/10.1158/1535-7163.22505877.v1
Autor:
Jordi Berenguer, Tonny Lagerweij, Xi Wen Zhao, Sophie Dusoswa, Petra van der Stoop, Bart Westerman, Mark C. de Gooijer, Marloes Zoetemelk, Anoek Zomer, Matheus H. W. Crommentuijn, Laurine E. Wedekind, Àlan López-López, Alberta Giovanazzi, Marina Bruch-Oms, Ida H. van der Meulen-Muileman, Rogier M. Reijmers, Toin H. van Kuppevelt, Juan-Jesús García-Vallejo, Yvette van Kooyk, Bakhos A. Tannous, Pieter Wesseling, Danijela Koppers-Lalic, W. Peter Vandertop, David P. Noske, Victor W. van Beusechem, Jacco van Rheenen, D. Michiel Pegtel, Olaf van Tellingen, Thomas Wurdinger
Publikováno v:
Journal of Extracellular Vesicles, Vol 7, Iss 1 (2018)
Cancer cells release extracellular vesicles (EVs) that contain functional biomolecules such as RNA and proteins. EVs are transferred to recipient cancer cells and can promote tumour progression and therapy resistance. Through RNAi screening, we ident
Externí odkaz:
https://doaj.org/article/0383b1c10fde4f49b4ec2946fa595f3c
Autor:
Victor W. van Beusechem, Agata Okonska, Ida H van der Meulen-Muileman, Rolf A. Stahel, Kathrin Oehl, Vasundhara Rao, Renée X. de Menezes, Walter Weder, Saskja Bühler, Emanuela Felley-Bosco, Manuel Ronner, Lorenza Penengo, Egbert F. Smit, Martin Wipplinger, Maxime Blijlevens
Publikováno v:
Molecular Cancer Therapeutics, 19(2), 552-563. AMER ASSOC CANCER RESEARCH
Okonska, A, Bühler, S, Rao, V, Ronner, M, Blijlevens, M, van der Meulen-Muileman, I H, de Menezes, R X, Wipplinger, M, Oehl, K, Smit, E F, Weder, W, Stahel, R A, Penengo, L, van Beusechem, V W & Felley-Bosco, E 2020, ' Functional genomic screen in mesothelioma reveals that loss of function of BRCA1-associated-protein-1 induces chemoresistance to ribonucleotide reductase inhibition ', Molecular Cancer Therapeutics, vol. 19, no. 2, pp. 552-563 . https://doi.org/10.1158/1535-7163.MCT-19-0356
Molecular Cancer Therapeutics, 19(2), 552-563. American Association for Cancer Research Inc.
Okonska, A, Bühler, S, Rao, V, Ronner, M, Blijlevens, M, van der Meulen-Muileman, I H, de Menezes, R X, Wipplinger, M, Oehl, K, Smit, E F, Weder, W, Stahel, R A, Penengo, L, van Beusechem, V W & Felley-Bosco, E 2020, ' Functional genomic screen in mesothelioma reveals that loss of function of BRCA1-associated-protein-1 induces chemoresistance to ribonucleotide reductase inhibition ', Molecular Cancer Therapeutics, vol. 19, no. 2, pp. 552-563 . https://doi.org/10.1158/1535-7163.MCT-19-0356
Molecular Cancer Therapeutics, 19(2), 552-563. American Association for Cancer Research Inc.
Loss of function of BRCA1-associated protein 1 (BAP1) is observed in about 50% of malignant pleural mesothelioma (MPM) cases. The aim of this study was to investigate whether this aspect could be exploited for targeted therapy. A genetically engineer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16c8fe5f2ce1c029b112525394eef696
http://hdl.handle.net/1887/3184836
http://hdl.handle.net/1887/3184836
Autor:
Victor W. van Beusechem, Ida H van der Meulen-Muileman, Egbert F. Smit, Renée X. de Menezes, Maxime Blijlevens
Publikováno v:
Oncogene, 38(21), 4142-4153. Nature Publishing Group
Blijlevens, M, van der Meulen-Muileman, I H, de Menezes, R X, Smit, E F & van Beusechem, V W 2019, ' High-throughput RNAi screening reveals cancer-selective lethal targets in the RNA spliceosome ', Oncogene, vol. 38, no. 21, pp. 4142-4153 . https://doi.org/10.1038/s41388-019-0711-z
Blijlevens, M, van der Meulen-Muileman, I H, de Menezes, R X, Smit, E F & van Beusechem, V W 2019, ' High-throughput RNAi screening reveals cancer-selective lethal targets in the RNA spliceosome ', Oncogene, vol. 38, no. 21, pp. 4142-4153 . https://doi.org/10.1038/s41388-019-0711-z
Novel therapeutic strategies for non-small-cell lung cancer (NSCLC) are urgently needed. RNA splicing, orchestrated by the spliceosome, is deregulated in many forms of cancer, including NSCLC. Here, we performed high-throughput screening with a small
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ed8d1680fceca7a745e47251950eb9a
https://research.vumc.nl/en/publications/71a4345e-0825-4361-9400-ddb557e2c914
https://research.vumc.nl/en/publications/71a4345e-0825-4361-9400-ddb557e2c914
Autor:
Olaf van Tellingen, Juan J. Garcia-Vallejo, Tonny Lagerweij, D. Michiel Pegtel, Alan Lopez-Lopez, Alberta Giovanazzi, Danijela Koppers-Lalic, Yvette van Kooyk, Thomas Wurdinger, Rogier M. Reijmers, Xi Wen Zhao, Mark C. de Gooijer, Toin H. van Kuppevelt, Victor W. van Beusechem, David P. Noske, Sophie A. Dusoswa, W. Peter Vandertop, Laurine E. Wedekind, Jordi Berenguer, Jacco van Rheenen, Matheus H.W. Crommentuijn, Marina Bruch-Oms, Anoek Zomer, Petra van der Stoop, Bart A. Westerman, Marloes Zoetemelk, Pieter Wesseling, Bakhos A. Tannous, Ida H van der Meulen-Muileman
Publikováno v:
Journal of extracellular vesicles, 7(1):1446660. Taylor and Francis Ltd.
Berenguer, J, Lagerweij, T, Zhao, X W, Dusoswa, S, van der Stoop, P, Westerman, B, de Gooijer, M C, Zoetemelk, M, Zomer, A, Crommentuijn, M H W, Wedekind, L E, López-López, À, Giovanazzi, A, Bruch-Oms, M, Meulen-Muileman, I H V D, Reijmers, R M, van Kuppevelt, T H, García-Vallejo, J J, van Kooyk, Y, Tannous, B A, Wesseling, P, Koppers-Lalic, D, Vandertop, W P, Noske, D P, van Beusechem, V W, van Rheenen, J, Pegtel, D M, van Tellingen, O & Wurdinger, T 2018, ' Glycosylated extracellular vesicles released by glioblastoma cells are decorated by CCL18 allowing for cellular uptake via chemokine receptor CCR8 ', Journal of Extracellular Vesicles, vol. 7, no. 1, 1446660 . https://doi.org/10.1080/20013078.2018.1446660, https://doi.org/10.1080/20013078.2018.1446660
Journal of Extracellular Vesicles, 7
Journal of Extracellular Vesicles, 7, 1
Journal of Extracellular Vesicles, Vol 7, Iss 1 (2018)
Journal of Extracellular Vesicles, 7(1). Taylor and Francis Ltd.
Journal of Extracellular Vesicles
Journal of Extracellular Vesicles, 7(1):1446660. Taylor and Francis Ltd.
Berenguer, J, Lagerweij, T, Zhao, X W, Dusoswa, S, van der Stoop, P, Westerman, B, de Gooijer, M C, Zoetemelk, M, Zomer, A, Crommentuijn, M H W, Wedekind, L E, López-López, À, Giovanazzi, A, Bruch-Oms, M, Meulen-Muileman, I H V D, Reijmers, R M, van Kuppevelt, T H, García-Vallejo, J J, van Kooyk, Y, Tannous, B A, Wesseling, P, Koppers-Lalic, D, Vandertop, W P, Noske, D P, van Beusechem, V W, van Rheenen, J, Pegtel, D M, van Tellingen, O & Wurdinger, T 2018, ' Glycosylated extracellular vesicles released by glioblastoma cells are decorated by CCL18 allowing for cellular uptake via chemokine receptor CCR8 ', Journal of Extracellular Vesicles, vol. 7, no. 1, 1446660 . https://doi.org/10.1080/20013078.2018.1446660, https://doi.org/10.1080/20013078.2018.1446660
Journal of Extracellular Vesicles, 7
Journal of Extracellular Vesicles, 7, 1
Journal of Extracellular Vesicles, Vol 7, Iss 1 (2018)
Journal of Extracellular Vesicles, 7(1). Taylor and Francis Ltd.
Journal of Extracellular Vesicles
Journal of Extracellular Vesicles, 7(1):1446660. Taylor and Francis Ltd.
Contains fulltext : 193223.pdf (Publisher’s version ) (Open Access) Cancer cells release extracellular vesicles (EVs) that contain functional biomolecules such as RNA and proteins. EVs are transferred to recipient cancer cells and can promote tumou
Autor:
Renee X. de Menezes, Maxime Blijlevens, Ida H van der Meulen-Muileman, Egbert F. Smit, Ellen Siebring-van Olst, Victor W. van Beusechem
Publikováno v:
Siebring-van Olst, E, Blijlevens, M, de Menezes, R X, van der Meulen-Muileman, I H, Smit, E F & van Beusechem, V W 2017, ' A genome-wide siRNA screen for regulators of tumor suppressor p53 activity in human non-small cell lung cancer cells identifies components of the RNA splicing machinery as targets for anticancer treatment ', Molecular oncology, vol. 11, no. 5, pp. 534-551 . https://doi.org/10.1002/1878-0261.12052
Molecular Oncology
Molecular oncology, 11(5), 534-551. Elsevier
Molecular Oncology
Molecular oncology, 11(5), 534-551. Elsevier
Reinstating wild-type tumor suppressor p53 activity could be a valuable option for the treatment of cancer. To contribute to development of new treatment options for non-small cell lung cancer (NSCLC), we performed genome-wide siRNA screens for deter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea5b7068e7252167cdef214625d623d2
https://research.vumc.nl/en/publications/cb4db343-196a-4b82-a330-11ff51d14a08
https://research.vumc.nl/en/publications/cb4db343-196a-4b82-a330-11ff51d14a08
Autor:
Victor W. van Beusechem, Renée M Overmeer, Paul van der Valk, Winald R. Gerritsen, Sander Idema, W. Peter Vandertop, Clemens M F Dirven, Ida H van der Meulen-Muileman, Martine L.M. Lamfers, Sharif Moeniralm, Lisette Bosscher, S. Heukelom
Publikováno v:
Clinical Cancer Research, 13(24), 7451-7458. American Association for Cancer Research Inc.
Clinical Cancer Research, 13(24), 7451-8. American Association for Cancer Research Inc.
Clinical cancer research, 13(24), 7451-7458. American Association for Cancer Research Inc.
Lamfers, M L M, Idema, S, Bosscher, L, Heukelom, S, Moeniralm, S, van der Meulen-Muileman, I H, Overmeer, R M, van der Valk, P, van Beusechem, V W, Gerritsen, W R, Vandertop, W P & Dirven, C M F 2007, ' Differential effects of combined Ad5-delta 24RGD and radiation therapy in in vitro versus in vivo models of malignant glioma ', Clinical Cancer Research, vol. 13, no. 24, pp. 7451-8 . https://doi.org/10.1158/1078-0432.CCR-07-1265
Clinical Cancer Research, 13(24), 7451-8. American Association for Cancer Research Inc.
Clinical cancer research, 13(24), 7451-7458. American Association for Cancer Research Inc.
Lamfers, M L M, Idema, S, Bosscher, L, Heukelom, S, Moeniralm, S, van der Meulen-Muileman, I H, Overmeer, R M, van der Valk, P, van Beusechem, V W, Gerritsen, W R, Vandertop, W P & Dirven, C M F 2007, ' Differential effects of combined Ad5-delta 24RGD and radiation therapy in in vitro versus in vivo models of malignant glioma ', Clinical Cancer Research, vol. 13, no. 24, pp. 7451-8 . https://doi.org/10.1158/1078-0432.CCR-07-1265
Purpose: The integrin-targeted conditionally replicating adenovirus Ad5-Δ24RGD has been shown to possess strong oncolytic activity in experimental tumors and is currently being developed toward phase I clinical evaluation for ovarian cancer and mali