Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Ida De Fino"'
Autor:
Federica De Leo, Alice Rossi, Francesco De Marchis, Cristina Cigana, Medede Melessike, Giacomo Quilici, Ida De Fino, Malisa Vittoria Mantonico, Chantal Fabris, Alessandra Bragonzi, Marco Emilio Bianchi, Giovanna Musco
Publikováno v:
Molecular Medicine, Vol 28, Iss 1, Pp 1-11 (2022)
Abstract Background High-mobility group box 1 protein (HMGB1) is an ubiquitous nuclear protein that once released in the extracellular space acts as a Damage Associated Molecular Pattern and promotes inflammation. HMGB1 is significantly elevated duri
Externí odkaz:
https://doaj.org/article/597732033346460b8156adaa2da0608d
Autor:
Chiara Tupini, Adriana Chilin, Alice Rossi, Ida De Fino, Alessandra Bragonzi, Elisabetta D’Aversa, Lucia Carmela Cosenza, Christian Vaccarin, Gianni Sacchetti, Monica Borgatti, Anna Tamanini, Maria Cristina Dechecchi, Francesca Sanvito, Roberto Gambari, Giulio Cabrini, Ilaria Lampronti
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 22, p 14483 (2022)
A series of new-generation TMA (4,6,4′-trimethyl angelicin) analogues was projected and synthetized in order to ameliorate anti-inflammatory activity, with reduced or absent toxicity. Since the NF-κB transcription factor (TF) plays a critical role
Externí odkaz:
https://doaj.org/article/44a522bed2fa4ba4a4fa5511e2829d0f
Autor:
Licia Totani, Concetta Amore, Antonio Piccoli, Giuseppe Dell’Elba, Angelo Di Santo, Roberto Plebani, Romina Pecce, Nicola Martelli, Alice Rossi, Serena Ranucci, Ida De Fino, Paolo Moretti, Alessandra Bragonzi, Mario Romano, Virgilio Evangelista
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Neutrophilic inflammation is a key determinant of cystic fibrosis (CF) lung disease. Neutrophil-derived free DNA, released in the form of extracellular traps (NETs), significantly correlates with impaired lung function in patients with CF, underlying
Externí odkaz:
https://doaj.org/article/ca1fa9b109974680beb3ba1817622c98
Autor:
Silvia Ferrara, Alice Rossi, Serena Ranucci, Ida De Fino, Alessandra Bragonzi, Cristina Cigana, Giovanni Bertoni
Publikováno v:
mSphere, Vol 5, Iss 5 (2020)
ABSTRACT Bacterial small RNAs play a remarkable role in the regulation of functions involved in host-pathogen interaction. ErsA is a small RNA of Pseudomonas aeruginosa that contributes to the regulation of bacterial virulence traits such as biofilm
Externí odkaz:
https://doaj.org/article/33761bc0e1bc4518858f439be19feeb4
Autor:
Noemi Poerio, Federica De Santis, Alice Rossi, Serena Ranucci, Ida De Fino, Ana Henriquez, Marco M. D’Andrea, Fabiana Ciciriello, Vincenzina Lucidi, Roberto Nisini, Alessandra Bragonzi, Maurizio Fraziano
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Despite intensive antimicrobial and anti-inflammatory therapies, cystic fibrosis (CF) patients are subjected to chronic infections due to opportunistic pathogens, including multidrug resistant (MDR) Pseudomonas aeruginosa. Macrophages from CF patient
Externí odkaz:
https://doaj.org/article/02a8ed2fc956448eaf6d2a7d63d81e11
Autor:
Giovanni Bacci, Alice Rossi, Federica Armanini, Lisa Cangioli, Ida De Fino, Nicola Segata, Alessio Mengoni, Alessandra Bragonzi, Annamaria Bevivino
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 22, p 12169 (2021)
Cystic fibrosis (CF) disease leads to altered lung and gut microbiomes compared to healthy subjects. The magnitude of this dysbiosis is influenced by organ-specific microenvironmental conditions at different stages of the disease. However, how this g
Externí odkaz:
https://doaj.org/article/912967eee91345e895c0a57e24294f96
Autor:
Antimo Cutone, Maria Stefania Lepanto, Luigi Rosa, Mellani Jinnett Scotti, Alice Rossi, Serena Ranucci, Ida De Fino, Alessandra Bragonzi, Piera Valenti, Giovanni Musci, Francesca Berlutti
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 9, p 2128 (2019)
Cystic fibrosis (CF) is a genetic disorder affecting several organs including airways. Bacterial infection, inflammation and iron dysbalance play a major role in the chronicity and severity of the lung pathology. The aim of this study was to investig
Externí odkaz:
https://doaj.org/article/a64cb4282e23409bb431089a903a685d
Autor:
Nicola Ivan Lorè, Noemi Veraldi, Camilla Riva, Barbara Sipione, Lorenza Spagnuolo, Ida De Fino, Medede Melessike, Elisa Calzi, Alessandra Bragonzi, Annamaria Naggi, Cristina Cigana
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 1, p 207 (2018)
Several chronic respiratory diseases are characterized by recurrent and/or persistent infections, chronic inflammatory responses and tissue remodeling, including increased levels of glycosaminoglycans which are known structural components of the airw
Externí odkaz:
https://doaj.org/article/8f188bb8864949dc91b0044ac055593c
Autor:
Emanuela Caci, Paolo Scudieri, Emma Di Carlo, Patrizia Morelli, Silvia Bruno, Ida De Fino, Alessandra Bragonzi, Ambra Gianotti, Elvira Sondo, Loretta Ferrera, Alessandro Palleschi, Luigi Santambrogio, Roberto Ravazzolo, Luis J V Galietta
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0131775 (2015)
Induction of mucus hypersecretion in the airway epithelium by Th2 cytokines is associated with the expression of TMEM16A, a Ca2+-activated Cl- channel. We asked whether exposure of airway epithelial cells to bacterial components, a condition that mim
Externí odkaz:
https://doaj.org/article/d779221725f04b499ed7db0ee4004618
Autor:
Maura De Simone, Lorenza Spagnuolo, Nicola Ivan Lorè, Giacomo Rossi, Cristina Cigana, Ida De Fino, Fuad A Iraqi, Alessandra Bragonzi
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106873 (2014)
Pseudomonas aeruginosa is a common cause of healthcare-associated infections including pneumonia, bloodstream, urinary tract, and surgical site infections. The clinical outcome of P. aeruginosa infections may be extremely variable among individuals a
Externí odkaz:
https://doaj.org/article/50470abe3d3a46d28202947ee2b58ea2