Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Ida De Fino"'
Autor:
Federica De Leo, Alice Rossi, Francesco De Marchis, Cristina Cigana, Medede Melessike, Giacomo Quilici, Ida De Fino, Malisa Vittoria Mantonico, Chantal Fabris, Alessandra Bragonzi, Marco Emilio Bianchi, Giovanna Musco
Publikováno v:
Molecular Medicine, Vol 28, Iss 1, Pp 1-11 (2022)
Abstract Background High-mobility group box 1 protein (HMGB1) is an ubiquitous nuclear protein that once released in the extracellular space acts as a Damage Associated Molecular Pattern and promotes inflammation. HMGB1 is significantly elevated duri
Externí odkaz:
https://doaj.org/article/597732033346460b8156adaa2da0608d
Autor:
Licia Totani, Concetta Amore, Antonio Piccoli, Giuseppe Dell’Elba, Angelo Di Santo, Roberto Plebani, Romina Pecce, Nicola Martelli, Alice Rossi, Serena Ranucci, Ida De Fino, Paolo Moretti, Alessandra Bragonzi, Mario Romano, Virgilio Evangelista
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Neutrophilic inflammation is a key determinant of cystic fibrosis (CF) lung disease. Neutrophil-derived free DNA, released in the form of extracellular traps (NETs), significantly correlates with impaired lung function in patients with CF, underlying
Externí odkaz:
https://doaj.org/article/ca1fa9b109974680beb3ba1817622c98
Autor:
Silvia Ferrara, Alice Rossi, Serena Ranucci, Ida De Fino, Alessandra Bragonzi, Cristina Cigana, Giovanni Bertoni
Publikováno v:
mSphere, Vol 5, Iss 5 (2020)
ABSTRACT Bacterial small RNAs play a remarkable role in the regulation of functions involved in host-pathogen interaction. ErsA is a small RNA of Pseudomonas aeruginosa that contributes to the regulation of bacterial virulence traits such as biofilm
Externí odkaz:
https://doaj.org/article/33761bc0e1bc4518858f439be19feeb4
Autor:
Noemi Poerio, Federica De Santis, Alice Rossi, Serena Ranucci, Ida De Fino, Ana Henriquez, Marco M. D’Andrea, Fabiana Ciciriello, Vincenzina Lucidi, Roberto Nisini, Alessandra Bragonzi, Maurizio Fraziano
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Despite intensive antimicrobial and anti-inflammatory therapies, cystic fibrosis (CF) patients are subjected to chronic infections due to opportunistic pathogens, including multidrug resistant (MDR) Pseudomonas aeruginosa. Macrophages from CF patient
Externí odkaz:
https://doaj.org/article/02a8ed2fc956448eaf6d2a7d63d81e11
Autor:
Emanuela Caci, Paolo Scudieri, Emma Di Carlo, Patrizia Morelli, Silvia Bruno, Ida De Fino, Alessandra Bragonzi, Ambra Gianotti, Elvira Sondo, Loretta Ferrera, Alessandro Palleschi, Luigi Santambrogio, Roberto Ravazzolo, Luis J V Galietta
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0131775 (2015)
Induction of mucus hypersecretion in the airway epithelium by Th2 cytokines is associated with the expression of TMEM16A, a Ca2+-activated Cl- channel. We asked whether exposure of airway epithelial cells to bacterial components, a condition that mim
Externí odkaz:
https://doaj.org/article/d779221725f04b499ed7db0ee4004618
Autor:
Maura De Simone, Lorenza Spagnuolo, Nicola Ivan Lorè, Giacomo Rossi, Cristina Cigana, Ida De Fino, Fuad A Iraqi, Alessandra Bragonzi
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106873 (2014)
Pseudomonas aeruginosa is a common cause of healthcare-associated infections including pneumonia, bloodstream, urinary tract, and surgical site infections. The clinical outcome of P. aeruginosa infections may be extremely variable among individuals a
Externí odkaz:
https://doaj.org/article/50470abe3d3a46d28202947ee2b58ea2
Autor:
Roslen Bondí, Marco Messina, Ida De Fino, Alessandra Bragonzi, Giordano Rampioni, Livia Leoni
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112105 (2014)
In Pseudomonas aeruginosa quorum sensing (QS) activates the production of virulence factors, playing a critical role in pathogenesis. Multiple negative regulators modulate the timing and the extent of the QS response either in the pre-quorum or post-
Externí odkaz:
https://doaj.org/article/e4bc295c73e44010bffa9be552d499fc
Autor:
Nicola Ivan Lorè, Cristina Cigana, Ida De Fino, Camilla Riva, Mario Juhas, Stephan Schwager, Leo Eberl, Alessandra Bragonzi
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35648 (2012)
The opportunistic pathogen Pseudomonas aeruginosa is able to thrive in diverse ecological niches and to cause serious human infection. P. aeruginosa environmental strains are producing various virulence factors that are required for establishing acut
Externí odkaz:
https://doaj.org/article/888197b5289c452d9a19fe201b17cd6f
Autor:
Alice Rossi, Alessandra Bragonzi, Melessike Medede, Ida De Fino, Giuseppe Lippi, Marco Prosdocimi, Anna Tamanini, Giulio Cabrini, Maria Cristina Dechecchi
Publikováno v:
Journal of Cystic Fibrosis. 22:156-160
We previously demonstrated that β-sitosterol (BSS) inhibits the expression of the chemokine IL-8 in CF bronchial epithelial cells exposed to P. aeruginosa. In the mouse model of lung chronic infection, herein shown, BSS significantly reduced leukocy
Autor:
Chiara Tupini, Adriana Chilin, Alice Rossi, Ida De Fino, Alessandra Bragonzi, Elisabetta D’Aversa, Lucia Carmela Cosenza, Christian Vaccarin, Gianni Sacchetti, Monica Borgatti, Anna Tamanini, Maria Cristina Dechecchi, Francesca Sanvito, Roberto Gambari, Giulio Cabrini, Ilaria Lampronti
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 22; Pages: 14483
A series of new-generation TMA (4,6,4′-trimethyl angelicin) analogues was projected and synthetized in order to ameliorate anti-inflammatory activity, with reduced or absent toxicity. Since the NF-κB transcription factor (TF) plays a critical role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc3db973aa8689aa0a74a0e8cb011462
https://hdl.handle.net/11562/1079851
https://hdl.handle.net/11562/1079851