Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Ida Aronchik"'
Autor:
Victor Moreno, Maria Vieito, Juan Manuel Sepulveda, Vladimir Galvao, Tatiana Hernández-Guerrero, Bernard Doger, Omar Saavedra, Carmelo Carlo-Stella, Jean-Marie Michot, Antoine Italiano, Massimo Magagnoli, Cecilia Carpio, Antonio Pinto, Rafael Sarmiento, Barbara Amoroso, Ida Aronchik, Ellen Filvaroff, Bishoy Hanna, Xin Wei, Zariana Nikolova, Irene Braña
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Bromodomain and extraterminal proteins (BET) are reported as targets for anticancer therapy. Here, the authors report the final results of a phase I clinical trial of the BET inhibitor trotabresib in patients with solid tumours and diffuse large B-ce
Externí odkaz:
https://doaj.org/article/a3d6902fdf494d03bb252c7609dbec45
Autor:
Antoine Hollebecque, Stefania Salvagni, Ruth Plummer, Patricia Niccoli, Jaume Capdevila, Giuseppe Curigliano, Victor Moreno, Filippo de Braud, Sonia Gonzalez de Villambrosia, Patricia Martin‐Romano, Eric Baudin, Marina Arias, Juan de Alvaro, Josep L. Parra‐Palau, Tania Sánchez‐Pérez, Ida Aronchik, Ellen H. Filvaroff, Manisha Lamba, Zariana Nikolova, Johann S. de Bono
Publikováno v:
Scientia
Lysine-specific demethylase 1 (LSD1) inhibitor; Neuroendocrine tumor; Non-Hodgkin lymphoma Tumor neuroendocrino; Linfoma no Hodgkin; Inhibidores de desmetilasa-1 específica a lisina Tumor neuroendocrí; Limfoma no Hodgkin; Inhibidor de la desmetilas
Autor:
Ellen H. Filvaroff, Gordon L. Bray, Konstantinos Mavrommatis, Tao Shi, Winfried Elis, Mehnaz Malek, Lisa Beebe, Lixin Qiao, Terri Jones, Carmen Barnes, Matt Labenski, Yumin Dai, Ida Aronchik
Supplementary figure legends and supplementary materials and methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4adb15c082041175df0f7d43940ae6e3
https://doi.org/10.1158/1541-7786.22512627
https://doi.org/10.1158/1541-7786.22512627
Autor:
Anne B. Jefferson, Cynthia M. Shafer, Eleni Venetsanakos, Elizabeth Ornelas, Catherine A. Luu, Mika K. Lindvall, Jiong Lan, William F. Estacio, Laura V. Doyle, Mercedita Del Rosario, Kenneth Crawford, Stephen E. Basham, Brent A. Appleton, Ida Aronchik
PDF file - 166K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08ad7594fcd5df49250ddfdaff9459d2
https://doi.org/10.1158/1541-7786.22511388
https://doi.org/10.1158/1541-7786.22511388
Autor:
Anne B. Jefferson, Cynthia M. Shafer, Eleni Venetsanakos, Elizabeth Ornelas, Catherine A. Luu, Mika K. Lindvall, Jiong Lan, William F. Estacio, Laura V. Doyle, Mercedita Del Rosario, Kenneth Crawford, Stephen E. Basham, Brent A. Appleton, Ida Aronchik
PDF file - 74K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab586f9613d97b5fef19284a31f81a52
https://doi.org/10.1158/1541-7786.22511394
https://doi.org/10.1158/1541-7786.22511394
Autor:
Ellen H. Filvaroff, Gordon L. Bray, Konstantinos Mavrommatis, Tao Shi, Winfried Elis, Mehnaz Malek, Lisa Beebe, Lixin Qiao, Terri Jones, Carmen Barnes, Matt Labenski, Yumin Dai, Ida Aronchik
Table S1. Summary of CC-90003 specificity data resulting from cellular and biochemical assays. Table S2. Response of BRAF mutant cell lines to CC-90003 ERK 1/2 inhibition. Table S3. Summary of dose finding efficacy study in HCT-116 xenograft model. F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e849dfd569bc7b70d64cf4940b8fb52e
https://doi.org/10.1158/1541-7786.22512630.v1
https://doi.org/10.1158/1541-7786.22512630.v1
Autor:
Anne B. Jefferson, Cynthia M. Shafer, Eleni Venetsanakos, Elizabeth Ornelas, Catherine A. Luu, Mika K. Lindvall, Jiong Lan, William F. Estacio, Laura V. Doyle, Mercedita Del Rosario, Kenneth Crawford, Stephen E. Basham, Brent A. Appleton, Ida Aronchik
PDF file - 28K, Percent Inhibition of MDA-MB-231 or H358 cells when grown as colonies on Scivax plates in the presence of LJI308.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac94484c1d0dc1a9aeed55e1da54f5f1
https://doi.org/10.1158/1541-7786.22511382
https://doi.org/10.1158/1541-7786.22511382
Autor:
Anne B. Jefferson, Cynthia M. Shafer, Eleni Venetsanakos, Elizabeth Ornelas, Catherine A. Luu, Mika K. Lindvall, Jiong Lan, William F. Estacio, Laura V. Doyle, Mercedita Del Rosario, Kenneth Crawford, Stephen E. Basham, Brent A. Appleton, Ida Aronchik
PDF file - 650K, Figure S1. RSK N-terminal Kinase Directly Phosphorylates YB1 on Ser102. COS7 cells either (A) untransfected or (B) transiently expressing WT RSK2 or T493M RSK2 were placed under serum starvation conditions for 20 hrs, followed by 3 h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0775c12e2c455a77f0f6170b2bd449e4
https://doi.org/10.1158/1541-7786.22511391
https://doi.org/10.1158/1541-7786.22511391
Autor:
Anne B. Jefferson, Cynthia M. Shafer, Eleni Venetsanakos, Elizabeth Ornelas, Catherine A. Luu, Mika K. Lindvall, Jiong Lan, William F. Estacio, Laura V. Doyle, Mercedita Del Rosario, Kenneth Crawford, Stephen E. Basham, Brent A. Appleton, Ida Aronchik
The p90 ribosomal S6 kinase (RSK) family of serine/threonine kinases is expressed in a variety of cancers and its substrate phosphorylation has been implicated in direct regulation of cell survival, proliferation, and cell polarity. This study charac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8ae1dcb5259c892f097fe0a3db0af33
https://doi.org/10.1158/1541-7786.c.6539931.v1
https://doi.org/10.1158/1541-7786.c.6539931.v1
Autor:
Anne B. Jefferson, Cynthia M. Shafer, Eleni Venetsanakos, Elizabeth Ornelas, Catherine A. Luu, Mika K. Lindvall, Jiong Lan, William F. Estacio, Laura V. Doyle, Mercedita Del Rosario, Kenneth Crawford, Stephen E. Basham, Brent A. Appleton, Ida Aronchik
XLSX file - 27K, Competition binding of LJH685, LJI308, BI-D1870-AE, and FMK-PA at 10 microM concentration to either 96 or 492 kinases.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c710e99010aa509d4e83e6d2196235f
https://doi.org/10.1158/1541-7786.22511385.v1
https://doi.org/10.1158/1541-7786.22511385.v1