Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Ida Aka"'
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 2, Pp 692-701 (2021)
Although pharmacogenetic testing is becoming increasingly common across medical subspecialties, a broad range of utilization and implementation exists across pediatric centers. Large pediatric institutions that routinely use pharmacogenetics in their
Externí odkaz:
https://doaj.org/article/c8b2cc9e26bc49a8bd6ad877ef14041e
Publikováno v:
Drugs - Real World Outcomes, Vol 6, Iss 2, Pp 59-71 (2019)
Abstract Background Although risperidone is increasingly used for behavioral indications in children, the associated adverse events (AEs) are not well defined in this population. Objective We determined the incidence of and risk factors for AEs among
Externí odkaz:
https://doaj.org/article/31832421b38d45eebb7f9f0b29c743c3
Autor:
Sandra Kikano, Joseph Breeyear, Ida Aka, Todd L. Edwards, Sara L. Van Driest, Prince J. Kannankeril
Publikováno v:
American Heart Journal. 254:57-65
Acute kidney injury (AKI) complicates 30% to 50% of cardiac surgeries in pediatric patients. Genetic variants that affect renal blood flow and inflammation have been associated with AKI after cardiac surgery in diverse populations of adults but have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::394ecbaeee26d0c70c131fe9f310982c
https://doi.org/10.1016/j.ahj.2022.08.003
https://doi.org/10.1016/j.ahj.2022.08.003
Autor:
Ayesha Muhammad, Kelly A. Birdwell, Dan M. Roden, Sara L. Van Driest, Jonathan D. Mosley, Wei-Qi Wei, Adam S. Gordon, Ida Aka
Publikováno v:
Clin Pharmacol Ther
Pharmacogenomic studies have successfully identified variants – typically with large effect sizes in drug target and metabolism enzymes – that predict drug outcome phenotypes. However, these variants may account for a limited proportion of phenot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb195421cf13be20157139be1acbdac1
https://doi.org/10.1002/cpt.2323
https://doi.org/10.1002/cpt.2323
Autor:
Tamorah R Lewis Md PhD, Sydney R Rooney, Prince J. Kannankeril, Elaine L. Shelton, Christian M. Shaffer, Sara L. Van Driest, Jeff Reese, John M. Dagle, Ida Aka, Ronald I. Clyman, Kelli K. Ryckman
Publikováno v:
Pharmacogenomics
Pharmacogenomics, vol 20, iss 13
Pharmacogenomics, vol 20, iss 13
Aims: To identify clinical andgenetic factors associated with indomethacin treatment failure in preterm neonates with patent ductus arteriosus (PDA). Patients & Methods: This is a multicenter cohort study of 144 preterm infants (22–32 weeks gestati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85e6115b0c0dbd163fe890cb88bcf148
https://doi.org/10.2217/pgs-2019-0079
https://doi.org/10.2217/pgs-2019-0079
Publikováno v:
Drugs-Real World Outcomes
Drugs-Real World Outcomes, Vol 6, Iss 2, Pp 59-71 (2019)
Drugs-Real World Outcomes, Vol 6, Iss 2, Pp 59-71 (2019)
Background Although risperidone is increasingly used for behavioral indications in children, the associated adverse events (AEs) are not well defined in this population. Objective We determined the incidence of and risk factors for AEs among children
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feb2fcc203ddfb4eec813458ba25aefa
https://doi.org/10.1007/s40801-019-0151-7
https://doi.org/10.1007/s40801-019-0151-7
Autor:
Robert J. Carroll, Kazeem A Oshikoya, Sara L. Van Driest, Ida Aka, Angela C. Maxwell-Horn, Katelyn M. Neely, Dan M. Roden
Publikováno v:
Pediatric research
Background: There are few and conflicting data on the role of cytochrome P450 2D6 (CYP2D6) polymorphisms in relation to risperidone adverse events (AEs) in children. This study assessed the association between CYP2D6 metabolizer status and risk for r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d580ba3107744d7102a1d7fec056ac2
https://doi.org/10.1038/s41390-019-0305-z
https://doi.org/10.1038/s41390-019-0305-z
Publikováno v:
Pediatrics
OBJECTIVES: To determine the association between cytochrome P450 2C19 (CYP2C19) metabolizer status and risk for escitalopram and citalopram, collectively termed (es)citalopram, and sertraline adverse events (AEs) in children. METHODS: In this retrosp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aa98dfb34a206a2adda489fced07c0e
https://doi.org/10.1542/peds.2020-0957
https://doi.org/10.1542/peds.2020-0957
Autor:
Dan M. Roden, Angela C. Maxwell-Horn, Sara L. Van Driest, Kazeem A Oshikoya, Katelyn M. Rossow, Ida Aka
Publikováno v:
J Dev Behav Pediatr
Objective To determine the association between genetic variants reported to affect risperidone and adverse events (AEs) in children and adolescents. Methods Individuals aged 18 years or younger with ≥4 weeks of risperidone exposure in a deidentifie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::460e8c09345f612bdb81d1442ba6794e
https://pubmed.ncbi.nlm.nih.gov/33759847
https://pubmed.ncbi.nlm.nih.gov/33759847
Autor:
Kellie Liston, Edwin Doe, Alison G Grisso, Elande Baro, Hannah M. Emerson, Lilly Yen, Rosanna Fulchiero, Craig L K Boge, Ann W. McMahon, Jessica Gillon, Jennifer Hale, Phuong Lieu, Sara L. Van Driest, Susan E. Coffin, Julie S. Pingel, Van L Tran, Brittany L. Haltzman, Kevin J. Downes, Gerold T. Wharton, Ida Aka
Publikováno v:
J Pediatr
OBJECTIVE: To describe the epidemiology of and risk factors associated with acute kidney injury (AKI) during acyclovir treatment in neonates and infants. STUDY DESIGN: We conducted a multicenter (n = 4), retrospective cohort study of all hospitalized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4c2587fb31d2a5a1ca5f443aee1f635
https://doi.org/10.1016/j.jpeds.2019.12.056
https://doi.org/10.1016/j.jpeds.2019.12.056