Zobrazeno 1 - 10
of 874
pro vyhledávání: '"Id1"'
Autor:
Rini Arianti, Boglárka Ágnes Vinnai, Rahaf Alrifai, Gyath Karadsheh, Yousif Qais Al-Khafaji, Szilárd Póliska, Ferenc Győry, László Fésüs, Endre Kristóf
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Brown and beige adipocytes can be activated by β-adrenergic agonist via cAMP-dependent signaling. Performing RNA-sequencing analysis in human cervical area-derived adipocytes, we found that dibutyryl-cAMP, which can mimic in vivo stimulatio
Externí odkaz:
https://doaj.org/article/1caa261d52e4411ca8ef1f3261d0c7ac
Autor:
Pratham Phadte, Aniketh Bishnu, Pranay Dey, Manikandan M, Megha Mehrotra, Prerna Singh, Shritama Chakrabarty, Rounak Majumdar, Bharat Rekhi, Malay Patra, Abhijit De, Pritha Ray
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-23 (2024)
Abstract Background The mechanisms enabling dynamic shifts between drug-resistant and drug-sensitive states in cancer cells are still underexplored. This study investigated the role of targeted autophagic protein degradation in regulating ovarian can
Externí odkaz:
https://doaj.org/article/b30acfb5696144008e3ac1ccbfe7940d
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Hepatic alveolar echinococcosis is a zoonotic disease with a high incidence in western China, particularly affecting plateau areas such as Qinghai, Tibet, and Xinjiang. Research has indicated the presence of neovascularization in the peripheral infil
Externí odkaz:
https://doaj.org/article/6d995545739041a0828b5e672777b9d3
Autor:
Aleide S. Lima, Matheus F. Bezerra, Amanda Moreira-Aguiar, Isabel Weinhäuser, Bianca L. Santos, Raul M. Falcão, Maria L. Salustiano-Bandeira, Pedro L. Franca-Neto, Marinus M. Lima, Felipe Saldanha-Araujo, Juan L. Coelho-Silva, Diego A. Pereira-Martins, Marcos A. Bezerra, Antonio R. Lucena-Araujo
Publikováno v:
Hematology, Transfusion and Cell Therapy, Vol 46, Iss 3, Pp 250-255 (2024)
Introduction: The aberrant expression of the inhibitor of DNA binding (ID1) gene has been frequently associated with the leukemogenesis and prognostication acute myeloid leukemia (AML), although its clinical importance has never been investigated in
Externí odkaz:
https://doaj.org/article/7c1873776b3546389a46d5d239e18b9a
Akademický článek
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Autor:
Ander Puyalto, María Rodríguez-Remírez, Inés López, Irati Macaya, Elizabeth Guruceaga, María Olmedo, Anna Vilalta-Lacarra, Connor Welch, Sergio Sandiego, Silvestre Vicent, Karmele Valencia, Alfonso Calvo, Ruben Pio, Luis E. Raez, Christian Rolfo, Daniel Ajona, Ignacio Gil-Bazo
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-19 (2024)
Abstract Background The identification of novel therapeutic strategies to overcome resistance to the MEK inhibitor trametinib in mutant KRAS lung adenocarcinoma (LUAD) is a challenge. This study analyzes the effects of trametinib on Id1 protein, a ke
Externí odkaz:
https://doaj.org/article/a7f566efdb754d68bd28062af5ab4148
Publikováno v:
FEBS Open Bio, Vol 14, Iss 1, Pp 127-137 (2024)
Sorafenib resistance greatly restricts its clinical application in patients with hepatocellular carcinoma (HCC). Numerous studies have reported that ID1 exerts a crucial effect in cancer initiation and development. Our previous research revealed an i
Externí odkaz:
https://doaj.org/article/26f379da548340cbae3d022aeb24db1d
Akademický článek
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Publikováno v:
Advanced Science, Vol 10, Iss 35, Pp n/a-n/a (2023)
Abstract T helper type 9 (Th9) cells play important roles in immune responses by producing interleukin‐9 (IL‐9). Several transcription factors are responsible for Th9 cell differentiation; however, transcriptional regulation of Th9 cells is not f
Externí odkaz:
https://doaj.org/article/86f34fc2e3934eb6b5e1906acd966aa0