Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Icksoo Lee"'
Autor:
Lucynda Pham, Tasnim Arroum, Junmei Wan, Lauren Pavelich, Jamie Bell, Paul T. Morse, Icksoo Lee, Lawrence I. Grossman, Thomas H. Sanderson, Moh H. Malek, Maik Hüttemann
Publikováno v:
Redox Biology, Vol 78, Iss , Pp 103426- (2024)
Mitochondria are essential to cellular function as they generate the majority of cellular ATP, mediated through oxidative phosphorylation, which couples proton pumping of the electron transport chain (ETC) to ATP production. The ETC generates an elec
Externí odkaz:
https://doaj.org/article/73a08391ef804f41ac18e230747e8c3b
Autor:
Paul T. Morse, Junmei Wan, Tasnim Arroum, Mackenzie K. Herroon, Hasini A. Kalpage, Viktoriia Bazylianska, Icksoo Lee, Elisabeth I. Heath, Izabela Podgorski, Maik Hüttemann
Publikováno v:
Biomolecules, Vol 14, Iss 6, p 695 (2024)
Cytochrome c (Cytc) is important for both mitochondrial respiration and apoptosis, both of which are altered in cancer cells that switch to Warburg metabolism and manage to evade apoptosis. We earlier reported that lysine 53 (K53) of Cytc is acetylat
Externí odkaz:
https://doaj.org/article/e6eca88fec50491fa78d013545b3d355
Autor:
Paul T. Morse, Gonzalo Pérez-Mejías, Junmei Wan, Alice A. Turner, Inmaculada Márquez, Hasini A. Kalpage, Asmita Vaishnav, Matthew P. Zurek, Philipp P. Huettemann, Katherine Kim, Tasnim Arroum, Miguel A. De la Rosa, Dipanwita Dutta Chowdhury, Icksoo Lee, Joseph S. Brunzelle, Thomas H. Sanderson, Moh H. Malek, David Meierhofer, Brian F. P. Edwards, Irene Díaz-Moreno, Maik Hüttemann
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Skeletal muscle is more resilient to ischemia-reperfusion injury than other organs. Tissue specific post-translational modifications of cytochrome c (Cytc) are involved in ischemia-reperfusion injury by regulating mitochondrial respiration a
Externí odkaz:
https://doaj.org/article/af1ef7e675a5418daa91f2c38dad03d0
Autor:
Paul T. Morse, Samuel Tuck, Mike Kerns, Dennis J. Goebel, Junmei Wan, Tom Waddell, Joseph M. Wider, Charlotte L. Hüttemann, Moh H. Malek, Icksoo Lee, Thomas H. Sanderson, Maik Hüttemann
Publikováno v:
Bioengineering & Translational Medicine, Vol 8, Iss 3, Pp n/a-n/a (2023)
Abstract Noninvasive delivery of near‐infrared light (IRL) to human tissues has been researched as a treatment for several acute and chronic disease conditions. We recently showed that use of specific IRL wavelengths, which inhibit the mitochondria
Externí odkaz:
https://doaj.org/article/8d6506a1e2b94668af034e284dfa8782
Publikováno v:
Animal Cells and Systems, Vol 25, Iss 1, Pp 74-81 (2021)
Excessive alcohol consumption causes the cellular and tissue damage. The toxic metabolites of ethanol are harmful to multiple organ systems, such as the central nervous system, skeletal muscles, and liver, and cause alcohol-induced diseases like canc
Externí odkaz:
https://doaj.org/article/97b351010ad14f83ba5a3b313cf96fbe
Autor:
Thomas H. Sanderson, Joseph M. Wider, Icksoo Lee, Christian A. Reynolds, Jenney Liu, Bradley Lepore, Reneé Tousignant, Melissa J. Bukowski, Hollie Johnston, Alemu Fite, Sarita Raghunayakula, John Kamholz, Lawrence I. Grossman, Karin Przyklenk, Maik Hüttemann
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Abstract The interaction of light with biological tissue has been successfully utilized for multiple therapeutic purposes. Previous studies have suggested that near infrared light (NIR) enhances the activity of mitochondria by increasing cytochrome c
Externí odkaz:
https://doaj.org/article/d38358554de345238b2771e0cebf73a7
Autor:
Icksoo Lee
Publikováno v:
Cells, Vol 10, Iss 6, p 1346 (2021)
Numerous naturally occurring molecules have been studied for their beneficial health effects. Many compounds have received considerable attention for their potential medical uses. Among them, several substances have been found to improve mitochondria
Externí odkaz:
https://doaj.org/article/5e7ebdef944d41b18bd082a73dd303a2
Autor:
Viktoriia Bazylianska, Hasini A. Kalpage, Junmei Wan, Asmita Vaishnav, Gargi Mahapatra, Alice A. Turner, Dipanwita Dutta Chowdhury, Katherine Kim, Paul T. Morse, Icksoo Lee, Joseph S. Brunzelle, Lisa Polin, Prabal Subedi, Elisabeth I. Heath, Izabela Podgorski, Katrin Marcus, Brian F.P. Edwards, Maik Hüttemann
Publikováno v:
Cells, Vol 10, Iss 4, p 802 (2021)
Prostate cancer is the second leading cause of cancer-related death in men. Two classic cancer hallmarks are a metabolic switch from oxidative phosphorylation (OxPhos) to glycolysis, known as the Warburg effect, and resistance to cell death. Cytochro
Externí odkaz:
https://doaj.org/article/6e00941728914ae48661db14772c4844
Publikováno v:
Cells, Vol 9, Iss 8, p 1843 (2020)
We previously reported that serine-47 (S47) phosphorylation of cytochrome c (Cytc) in the brain results in lower cytochrome c oxidase (COX) activity and caspase-3 activity in vitro. We here analyze the effect of S47 modification in fibroblast cell li
Externí odkaz:
https://doaj.org/article/3bad47f449b94b1186a692dcd60157ad
Autor:
Yufen Xie, Sichang Zhou, Zhongliang Jiang, Jing Dai, Elizabeth E. Puscheck, Icksoo Lee, Graham Parker, Maik Hüttemann, Daniel A. Rappolee
Publikováno v:
Stem Cell Research, Vol 13, Iss 3, Pp 478-491 (2014)
Dysfunctional stem cell differentiation into placental lineages is associated with gestational diseases. Of the differentiated lineages available to trophoblast stem cells (TSC), elevated O2 and mitochondrial function are necessary to placental linea
Externí odkaz:
https://doaj.org/article/f69df3839103415f8070a42516127791