Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ichiro Tsujio"'
Autor:
Hiroshi Tsujimoto, Shinichiro Nakajima, Isseki Maeda, Madoka Tokuyama, Hitoshi Tanimukai, Yoshiaki Okamoto, Sho Goya, Yoshinobu Matsuda, Motoo Watanabe, Toshihiro Taira, Seitetsu Kanemura, Toshihiro Kai, Kiyozumi Takei, Akihiro Tokoro, Ichiro Tsujio, Yujiro Kashiwagi
Publikováno v:
American Journal of Hospice and Palliative Medicine®. 33:456-462
To compare the efficacy of antipsychotics (APs) for delirium treatment in patients with cancer, 27 patients treated with 1 of the 4 APs, haloperidol (HPD), risperidone (RIS), olanzapine (OLZ), and quetiapine (QTP), were divided into 2 groups: long ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcdad8c67b2606f7af02a1a48b5f10d7
https://doi.org/10.1177/1049909114565019
https://doi.org/10.1177/1049909114565019
Publikováno v:
FEBS Letters. 579:363-372
Protein phosphatase (PP)-2A, which regulates the phosphorylation of tau, is regulated by two endogenous inhibitor proteins, I(1)(PP2A) and I(2)(PP2A), in mammalian tissues. Here, we report the cloning of I(1)(PP2A) and I(2)(PP2A) from human brain, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1d2bb85c1b4f6d16f310bb7f67c2a6f
https://doi.org/10.1016/j.febslet.2004.11.097
https://doi.org/10.1016/j.febslet.2004.11.097
Autor:
Niloufar Haque, Sabiha Khatoon, Hitoshi Tanimukai, Jin-Jing Pei, Cheng-Xin Gong, Ezzat El-Akkad, Jian-Zhi Wang, Inge Grundke-Iqba, Ichiro Tsujio, K. Iqbal, Alejandra del C. Alonso
Publikováno v:
Journal of Molecular Neuroscience. 20:425-430
Neurofibrillary degeneration has primary and pivotal involvement in the pathogenesis of Alzheimer disease (AD) and other tauopathies. The inhibition of this lesion offers a promising therapeutic approach. The microtubule- associated protein (MAP) tau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be85ac27945798da11d5df1cd1809dac
https://doi.org/10.1385/jmn:20:3:425
https://doi.org/10.1385/jmn:20:3:425
Autor:
Sabiha Khatoon, Inge Grundke-Iqbal, Maria Nordlinder, Jin-Jing Pei, Khalid Iqbal, Masatoshi Takeda, Richard F. Cowburn, Toshihisa Tanaka, Bengt Winblad, Wen-Lin An, Irina Alafuzoff, Heiko Braak, Ichiro Tsujio
Publikováno v:
Acta Neuropathologica. 105:381-392
Protein kinase B (PKB) is an important intermediate in the phosphatidylinositol-3 kinase signaling cascade that acts to phosphorylate glycogen synthase kinase-3 (GSK-3) at its serine 9 residue, thereby inactivating it. Activated GSK-3 has been previo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7804c48e2a0f46276d50283df43b16e
https://doi.org/10.1007/s00401-002-0657-y
https://doi.org/10.1007/s00401-002-0657-y
Autor:
Masatoshi Takeda, Ichiro Tsujio, Toshihisa Tanaka, Takashi Nishikawa, Takashi Kudo, Kazuhiro Shinosaki
Publikováno v:
Alzheimer Disease and Associated Disorders. 14:S18-S24
The role of the phosphatidylinositol-3 kinase pathway in the hyperphosphorylation of tau protein was investigated in cultured cells. Human kidney 293T-cells were cotransfected with tau and glycogen synthase kinase-3 (GSK-3) genes or tau and protein k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fc5afef52f49266438aa09d15180bd2
https://doi.org/10.1097/00002093-200000001-00004
https://doi.org/10.1097/00002093-200000001-00004
Autor:
Norio Taniguchi, Masatoshi Takeda, Ichiro Tsujio, Norio Ogawa, Hisashi Tanii, Emi Iwata, Takashi Kudo, Masato Asanuma
Publikováno v:
Psychiatry and Clinical Neurosciences. 51:415-420
Using electrophoretic mobility-shift assay (EMSA), we examined DNA-binding activity of cAMP response element (CRE), onto its responsive element CRE, as well as TPA responsive element (TRE) in the medial hypothalamus and striatum of the experimental r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e819ef63e827411f487d29f80737eef9
https://doi.org/10.1111/j.1440-1819.1997.tb02610.x
https://doi.org/10.1111/j.1440-1819.1997.tb02610.x
Autor:
Inge Grundke-Iqbal, Jin-Jing Pei, Cheng-Xin Gong, Ichiro Tsujio, Jian-Zhi Wang, Ezzat El-Akkad, Niloufar Haque, Khalid Iqbal, Alejandra del C. Alonso, Sabiha Khatoon
Publikováno v:
Journal of molecular neuroscience : MN. 19(1-2)
Abnormally hyperphosphorylated tau which is the major protein subunit of paired helical filaments (PHF)/neurofibrillary tangles is the pivotal lesion in Alzheimer disease (AD) and related tauopathies. The cosegregation of tau mutations with disease i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad532749cafcba097ca071b900d2114c
https://pubmed.ncbi.nlm.nih.gov/12212801
https://pubmed.ncbi.nlm.nih.gov/12212801
Autor:
Takashi Morihara, Hiroshi Mori, Tatsuo Mima, Yuko Koike, Hitoshi Tanimukai, Koreaki Mori, Yu Nakamura, Masatoshi Takeda, Kazuhisa Nakao, Ichiro Tsujio, Shinji Tagami, Toshihisa Tanaka, Ryouta Hashimoto, Takashi Kudo
Publikováno v:
Psychiatry and clinical neurosciences. 54(2)
A biological marker for normal pressure hydrocephalus (NPH) is beneficial for evaluation of its severity and of indications for shunt operation. Tau protein was initially considered as a biological marker in cerebrospinal fluid (CSF) from Alzheimer's
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be8ba33f527fdc826498079cc224e669
https://pubmed.ncbi.nlm.nih.gov/10803815
https://pubmed.ncbi.nlm.nih.gov/10803815
Autor:
Ryota Hashimoto, Hitoshi Tanimukai, Masatoshi Takeda, Takashi Kudo, Ichiro Tsujio, Yu Nakamura
Publikováno v:
Psychiatry and clinical neurosciences. 53(5)
The abnormality of cytoskeletal proteins is related to Alzheimer's disease. Because neurofilament proteins (NF) are major cytoskeletal components of neurones, abnormality of NF may be involved in the pathology of disease. In this study, insoluble NF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6de05352fcf5f093604b1e029c8d021e
https://pubmed.ncbi.nlm.nih.gov/10595684
https://pubmed.ncbi.nlm.nih.gov/10595684