Výsledky vyhledávání

Risk assessment of diabetes mellitus using dried saliva spot followed by ultra-performance liquid chromatography with fluorescence and mass spectrometry

Autor: Yutaka Kitagawa, Kenichiro Todoroki, Masahiro Numako, Hajime Mizuno, Ichiro Noge, Toshimasa Toyo'oka

Publikováno v: Microchemical Journal. 142:202-207

The dried saliva spot (DSS) seems to be a convenient sampling technique for bioanalysis. In our previous research, the DSS sampling was used for the determination of dl -lactic acid (DL-LA) and the D/L ratio of diabetic, pre-diabetic and healthy pers

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ba7bce9297dbdbf53f06b408a83e305d
https://doi.org/10.1016/j.microc.2018.06.037

Zobrazit plný text záznamu

Determination of acetone in saliva by reversed-phase liquid chromatography with fluorescence detection and the monitoring of diabetes mellitus patients with ketoacidosis

Autor: Kenichiro Todoroki, Jun Zhe Min, Ichiro Noge, Yutaka Kitagawa, Toshimasa Toyo'oka, Koichi Inoue, Shinya Fujii, Toshio Maeda

Publikováno v: Clinica Chimica Acta. 430:140-144

Background In diabetes mellitus (DM) patients with ketoacidosis, ketone bodies, i.e., acetone, acetoacetic acid (AA) and β-hydroxybutyric acid (HA), are increased in the blood and urine. Acetone is also excreted by breathing due to the spontaneous d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a609947c88ff09ec24058684fa80b40
https://doi.org/10.1016/j.cca.2014.01.006

Zobrazit plný text záznamu

Changes in compliance with Japanese antiemetic guideline for chemotherapy-induced nausea and vomiting: a nationwide survey using a distributed research network

Autor: Masako Kondoh, Katsuhito Hori, Tomomi Kimura, Akira Nagayama, Midori Kimura, Tsuyoshi Iwasaki, Ichiro Noge, Hiroaki Utsugi, Hitoshi Atsumi, Norihiro Kobayashi, Masaki Nakamura

Publikováno v: Supportive Care in Cancer. 22:969-977

Prophylaxis of chemotherapy (CT)-induced nausea and vomiting (CINV) is important for patient's quality of life and adherence to CT. Neurokinin receptor antagonist (NK1 antagonist) was marketed in Japan in December 2009 and the first guideline for ant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::909476a1329da5c9903aaced6ef6b08e
https://doi.org/10.1007/s00520-013-2048-4

Zobrazit plný text záznamu

Influence of Anticancer Agents on Nutritional Factors

Autor: Akira Nagayama, Ichiro Noge, Toru Okada, Katsunori Sano, Yasuhide Yosida, Yasunari Kurita, Yuki Kato, Mitsuaki Suzuki, Kenichi Suzuki

Publikováno v: Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences). 33:229-234

CDDP(Cisplatin) and CBDCA(Carboplatin) are likely to cause nausea and vomiting,which are considered to be factors lowering QOL for patients undergoing chemotherapy.In the present study,our Nutrition Support Team(NST) investigated the influence of can

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0849406948dc982592eaa823ac8ee8ab
https://doi.org/10.5649/jjphcs.33.229

Zobrazit plný text záznamu

Dried Saliva Spot (DSS) as a Convenient and Reliable Sampling for Bioanalysis: An Application for the Diagnosis of Diabetes Mellitus

Autor: Takahiro Takayama, Jun Zhe Min, Toshimasa Toyo'oka, Hajime Mizuno, Yutaka Kitagawa, Ichiro Noge, Masahiro Numako, Kenichiro Todoroki

Publikováno v: Analytical chemistry. 88(1)

This paper proposes the dried saliva spot (DSS) as a convenient sampling technique for bioanalysis. The analytical method with the DSS was used for the determination of D,L-lactic acid (D,L-LA) and the D/L ratio of diabetic patients and prediabetic p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::446407446c6253fdbdee6fd58990d179
https://pubmed.ncbi.nlm.nih.gov/26629726

Zobrazit plný text záznamu

A novel approach for LC-MS/MS-based chiral metabolomics fingerprinting and chiral metabolomics extraction using a pair of enantiomers of chiral derivatization reagents

Autor: Toshimasa Toyo'oka, Kenichiro Todoroki, Takahiro Takayama, Hajime Mizuno, Koichi Inoue, Hiroyasu Akatsu, Toshiki Mochizuki, Ichiro Noge, Jun Zhe Min

Publikováno v: Analytica chimica acta. 898

Chiral metabolites are found in a wide variety of living organisms and some of them are understood to be physiologically active compounds and biomarkers. However, the overall analysis of chiral metabolomics is quite difficult due to the high number o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97015cc839b9b43b5b98cd67b97bbbcb
https://pubmed.ncbi.nlm.nih.gov/26526912

Zobrazit plný text záznamu

Profiling of chiral and achiral carboxylic acid metabolomics: synthesis and evaluation of triazine-type chiral derivatization reagents for carboxylic acids by LC-ESI-MS/MS and the application to saliva of healthy volunteers and diabetic patients

Autor: Yutaka Kitagawa, Ichiro Noge, Tomohiro Kuwabara, Toshio Maeda, Jun Zhe Min, Toshimasa Toyo'oka, Koichi Inoue, Kenichiro Todoroki, Takahiro Takayama

Publikováno v: Analytical and bioanalytical chemistry. 407(3)

Novel triazine-type chiral derivatization reagents, i.e., (S)-1-(4,6-dimethoxy-1,3,5-triazin-2-yl)pyrrolidin-3-amine (DMT-3(S)-Apy) and (S)-4,6-dimethoxy-N-(pyrrolidin-3-yl)-1,3,5-triazin-2-amine (DMT-1(S)-Apy), were developed for the highly sensitiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b34302a2a32850537bad3f7c6a95bcdd
https://pubmed.ncbi.nlm.nih.gov/25366977

Zobrazit plný text záznamu

Infiltration of M1 macrophages into adipose tissue of ddY-H mice preceding spontaneous appearances of insulin resistance

Autor: Toshio Maeda, Yoshiyuki Kagawa, Ichiro Noge

Publikováno v: Biologicalpharmaceutical bulletin. 36(5)

We have isolated insulin resistant mice (ddY-H mice) which are spontaneously induced at 12-weeks of age even if fed with the standard chow pellets. Since accumulated evidences have suggested that an appearance of insulin resistance is associated with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfd46dbec89f626568a33c652f9a6e3a
https://pubmed.ncbi.nlm.nih.gov/23420608

Zobrazit plný text záznamu

Simultaneous determination of DL-lactic acid and DL-3-hydroxybutyric acid enantiomers in saliva of diabetes mellitus patients by high-throughput LC-ESI-MS/MS

Autor: Haruhito Tsutsui, Toshio Maeda, Jun Zhe Min, Toshiki Mochizuki, Koichi Inoue, Toshimasa Toyo'oka, Yutaka Kitagawa, Ichiro Noge, Kenichiro Todoroki

Publikováno v: Analytical and bioanalytical chemistry. 404(6-7)

A simultaneous determination method for the enantiomers of chiral carboxylic acids by the combination of ultraperformance liquid chromatography and mass spectrometry (UPLC–MS/MS) has been developed. (S)(+)-1-(2-Pyrrolidinylmethyl)-pyrrolidine (S-PM

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::432b7b4129c45f4fbeaaf59c1fe4fd35
https://pubmed.ncbi.nlm.nih.gov/22895741

Zobrazit plný text záznamu

A new diabetic mouse model derived from the ddY strain

Autor: Yoshiyuki Kagawa, Toshio Maeda, Ichiro Noge

Publikováno v: Biologicalpharmaceutical bulletin. 33(6)

Selective breeding was used to isolate hyperglycemic (ddY-H) or normoglycemic (ddY-L) mice that had been induced by fasting and refeeding. Serum glucose levels 12 h after 48 h-fasting were high in male ddY-H mice, but relatively low in male ddY-L mic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de8cdaca3318e47811909def3b475fe8
https://pubmed.ncbi.nlm.nih.gov/20522964

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání