Molecular Reorganization during the Formation of the Human Skin Barrier Studied In Situ

Autor: Ichiro Iwai, Ali Narangifard, Lianne den Hollander, Christian L. Wennberg, HongMei Han, Bertil Daneholt, Magnus Lundborg, Lars Norlén, Erik Lindahl, Sergej Masich

Publikováno v: The Journal of investigative dermatology. 141(5)

In vertebrates, skin upholds homeostasis by preventing body water loss. The skin's permeability barrier is located intercellularly in the stratum corneum and consists of stacked lipid lamellae composed of ceramides, cholesterol, and free fatty acids.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b689d7b6e58775f8f5a4be393b4dc0c
https://pubmed.ncbi.nlm.nih.gov/33098827

Stratum Corneum Drying Drives Vertical Compression and Lipid Organization and Improves Barrier Function In vitro

Autor: Ichiro Iwai, Naomi Kunizawa, Eiichiro Yagi, Ichiro Hatta, Tetsuji Hirao

Publikováno v: Acta Dermato Venereologica. 93:138-143

The stratum corneum dehydrates after exogenous hydration due to skincare or bathing. In this study, sheets of stratum corneum were isolated from reconstructed human epidermis and the barrier function and structure of these sheets were assessed during

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2434ed9366ce72fe944d3927a145a868
https://doi.org/10.2340/00015555-1423

The Human Skin Barrier Is Organized as Stacked Bilayers of Fully Extended Ceramides with Cholesterol Molecules Associated with the Ceramide Sphingoid Moiety

Autor: Maria Bloksgaard, HongMei Han, Jamshed Anwar, Luis A. Bagatolli, Stina Svensson, Sergej Masich, Jonathan R. Brewer, Lars Norlén, Aurelie Laloeuf, Lars-Goran Ofverstedt, Ulf Skoglund, Daniel Nosek, Lianne den Hollander, Ichiro Iwai

Publikováno v: Iwai, I, Han, H, Hollander, L D, Svensson, S, Ofverstedt, L-G, Anwar, J, Brewer, J, Mølgaard, M B, Laloeuf, A, Nosek, D, Masich, S, Bagatolli, L A, Skoglund, U & Norlén, L 2012, ' The Human Skin Barrier Is Organized as Stacked Bilayers of Fully Extended Ceramides with Cholesterol Molecules Associated with the Ceramide Sphingoid Moiety ', Journal of Investigative Dermatology, vol. 132, no. 9, pp. 2215-2225 . https://doi.org/10.1038/jid.2012.43

The skin barrier is fundamental to terrestrial life and its evolution; it upholds homeostasis and protects against the environment. Skin barrier capacity is controlled by lipids that fill the extracellular space of the skin's surface layer-the stratu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fa23dbd1edbae252ee8af965ee32a25

Evaluation of fatigue strength of friction stir butt-welded aluminum alloy joints inclined to applied cyclic stress

Autor: Masaki Kumagai, Ichiro Iwai, Hiroto Katsuki, Shigenobu Kainuma

Publikováno v: International Journal of Fatigue. 30:870-876

Recently, fatigue tests have been performed to investigate the fatigue behavior of friction stir butt-welded aluminum alloy joints. However, the joints of more than 10 mm thick plates have rarely been tested, nor has the effect of the inclined angle

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::21814612f0cab4cfc024187b47af961a
https://doi.org/10.1016/j.ijfatigue.2007.06.007

Increased carbonyl protein levels in the stratum corneum of the face during winter

Autor: Ichiro Iwai, Nobuko Akutsu, Tetsuji Hirao, Y. Kobayashi

Publikováno v: International Journal of Cosmetic Science. 30:35-40

The stratum corneum (SC) is the interface between the body and the environment, and is continuously exposed to oxidative stress that results in carbonyl modification of proteins. We previously developed a simple and non-invasive method to assess the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6f370d9c578ea2ccd8524db318ef8480
https://doi.org/10.1111/j.1468-2494.2008.00422.x