Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Ichiro Hirahara"'
Publikováno v:
The Journal of Biochemistry.
Peritoneal dialysis (PD) is a blood purification treatment for patients with reduced renal function. However, the peritoneum is exposed to oxidative stress during PD and long-term PD results in peritoneal damage, leading to the termination of PD. Met
Autor:
Tetsu Akimoto, Eiji Kusano, Makoto Inoue, Yoshiyuki Morishita, Osamu Saito, Toshimi Imai, Shigeaki Muto, Daisuke Nagata, Ichiro Hirahara
Publikováno v:
BioMed Research International, Vol 2015 (2015)
BioMed Research International
BioMed Research International
Peritoneal deterioration causing structural changes and functional decline is a major complication of peritoneal dialysis (PD). The aim of this study was to explore effluent biomarkers reflecting peritoneal deterioration. In an animal study, rats wer
Autor:
Susumu Ookawara, Ichiro Hirahara, Yusuke Igarashi, Keiji Hirai, Yoshiyuki Morishita, Hiromichi Yoshizawa, Toshimi Imai, Kenichi Ishibashi
Publikováno v:
Journal of Visualized Experiments.
MicroRNAs (miRNAs) are small noncoding RNAs that regulate messenger RNA expression post-transcriptionally. The miRNA expression profile has been investigated in various organs and tissues in rat. However, standard methods for the purification of miRN
Autor:
Ichiro Hirahara, Susumu Ookawara, Kenichi Ishibashi, Yoshiyuki Morishita, Hiromichi Yoshizawa, Shigeaki Muto, Yusuke Igarashi, Reika Imai, Tetsu Akimoto, Toshimi Imai, Daisuke Nagata
Publikováno v:
Renal Failure
Background: Chronic inflammation of the peritoneum causes peritoneal injury in patients on peritoneal dialysis. Intercellular adhesion molecule-1 and its circulating form, soluble intercellular adhesion molecule-1, play pivotal roles in inflammation.
Autor:
Shigeaki Muto, Ichiro Hirahara, Tetsu Akimoto, Yoshiyuki Morishita, Daisuke Nagata, Osamu Saito, Eiji Kusano, Makoto Inoue
AIM: To investigate the efficacy of effluent biomarkers for peritoneal deterioration with functional decline in peritoneal dialysis (PD). METHODS: From January 2005 to March 2013, the subjects included 218 PD patients with end-stage renal disease at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2d89adbc42880d57a1e3286a0299af3
https://europepmc.org/articles/PMC4777793/
https://europepmc.org/articles/PMC4777793/
Publikováno v:
Renal failure. 38(2)
The epithelial-to-mesenchymal transition (EMT) of peritoneal mesothelial cells plays a pivotal role in the development of peritoneal fibrosis. The pathological effects of hypoxia on mesothelial cell EMT have not been fully elucidated. In this study,
Publikováno v:
Nephrology Dialysis Transplantation. 24:437-447
Background. The epithelial-to-mesenchymal transition (EMT) of mesothelial cells was observed in patients on peritoneal dialysis and may be involved in peritoneal thickening. Conventional peritoneal dialysis fluids (PDFs) that contain glucose degradat
Autor:
Ichiro Hirahara, Reika Imai, Shigeaki Muto, Tetsu Akimoto, Hiromichi Yoshizawa, Minami Watanabe, Yoshiyuki Morishita, Daisuke Nagata, Susumu Ookawara, Toshimi Imai
Publikováno v:
Translational research : the journal of laboratory and clinical medicine. 169
Peritoneal fibrosis (PF) is an intractable complication leading to peritoneal membrane failure in peritoneal dialysis (PD). The aim of this study was to identify microRNAs (miRNAs) involved in PF. Peritoneal tissue from a PF rat model was screened fo
Autor:
Akira Onishi, Shigeaki Muto, Eiji Kusano, Daisuke Nagata, Ichiro Hirahara, Toshimi Imai, Hideki Sato, Yoshiyuki Morishita
Publikováno v:
BioMed Research International
BioMed Research International, Vol 2015 (2015)
BioMed Research International, Vol 2015 (2015)
Peritoneal dialysis (PD) is a common treatment for patients with reduced or absent renal function. Long-term PD leads to peritoneal injury with structural changes and functional decline. At worst, peritoneal injury leads to encapsulating peritoneal s
Autor:
Keiya Ozawa, Eiji Kusano, Ichiro Hirahara, Akira Onishi, Masashi Urabe, Tetsu Akimoto, Shigeaki Muto, Daisuke Nagata
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 95(12)
Peritoneal fibrosis (PF), a serious pathophysiology of peritoneal dialysis (PD), is implicated in various types of chronic inflammation. In the present study, we examined the benefits of interleukin (IL)-10, which exerts anti-inflammatory effects, in