Zobrazeno 1 - 10
of 274
pro vyhledávání: '"Ichiro Hatta"'
Publikováno v:
Polymers, Vol 11, Iss 5, p 829 (2019)
Stratum corneum (SC), the outermost layer of human skin, acts as an intelligent physicochemical interface between the inside and the outside of our body. To make clear the relationship between structure and physical barrier properties of SC, we devel
Externí odkaz:
https://doaj.org/article/644727eb8d384e28a497e879814ec294
Publikováno v:
Pharmaceutics, Vol 9, Iss 3, p 26 (2017)
The intercellular lipids in the stratum corneum form structures composed of ordered phases with orthorhombic and hexagonal hydrocarbon-chain packing structures and, in addition, a structure composed of a disordered fluid phase. Although the fluid pha
Externí odkaz:
https://doaj.org/article/9c86b6705d4642bc894c38cfc9731138
Autor:
Ichiro Hatta
Publikováno v:
Dermato. 2:79-108
X-ray diffraction is one of the powerful tools in the study of a variety of structures in the stratum corneum at the molecular level. Resolving structural modifications during functioning is an important subject for clarifying the mechanism of operat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6347cdc82189f97eb8ab8a47ef511dda
https://doi.org/10.3390/dermato2030009
https://doi.org/10.3390/dermato2030009
Autor:
Tomonobu Uchino, Daichi Kamiya, Hiroaki Yagi, Hiyori Fujino-Shimaya, Ichiro Hatta, Shun Fujimori, Yasunori Miyazaki, Yukako Kirishita, Yuko Sano, Hajime Mizuno, Kenichiro Todoroki, Yoshiyuki Kagawa
Publikováno v:
Chemistry and Physics of Lipids. 254:105305
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5eb74f907645ac2e7e9bb43fc9048312
https://doi.org/10.1016/j.chemphyslip.2023.105305
https://doi.org/10.1016/j.chemphyslip.2023.105305
The effects of sphingomyelin synthase (SMS) deficiency on stratum corneum (SC) barrier function (skin permeability of the hydrophilic and lipophilic compounds) and SC lamellar structure are unknown. Skin permeability of the hydrophilic compound incre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00ee45ba29dc1db12adcd5ae53933182
https://doi.org/10.21203/rs.3.rs-1627640/v1
https://doi.org/10.21203/rs.3.rs-1627640/v1
Publikováno v:
International Journal of Cosmetic Science. 43:38-47
Polyols are moisturizers used in cosmetics. Using X-ray diffraction, we studied the moisturizingmechanism of polyol solutions in the stratum corneum (SC). We examined whether glycerol disrupts the ordered hydrocarbon chain packing structure in isolat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b639c6cfeb999d08c2b1238cf79d4eb2
https://doi.org/10.1111/ics.12664
https://doi.org/10.1111/ics.12664
Publikováno v:
Biochimica et biophysica acta. Biomembranes. 1864(9)
For analysis of the structure of human skin stratum corneum (SC), we introduced low-flux electron diffraction (ED) and developed a new statistical analysis method for obtained ED intensity profiles. By use of this method we compared the differences i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83dcde316520fa792115aaf6ced2af11
https://pubmed.ncbi.nlm.nih.gov/35504319
https://pubmed.ncbi.nlm.nih.gov/35504319
Publikováno v:
Journal of oleo science. 70(9)
Studies on the effectiveness of substances such as drugs and cosmetics that act on the skin require structural evidence at the molecular level in the stratum corneum to clarify their interaction with intercellular lipid and soft keratin. For this pur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86ee8b1eb91c985656891dfad1941f44
https://pubmed.ncbi.nlm.nih.gov/34373412
https://pubmed.ncbi.nlm.nih.gov/34373412
Autor:
Tomonori Suzuki, Kohta Sasaki, Sayaka Kato, Tomonobu Uchino, Ichiro Hatta, Yoshiyuki Kagawa, Yasunori Miyazaki
Publikováno v:
International Journal of Pharmaceutics. 555:259-269
The mechanism underlying the skin permeation of flurbiprofen (FLU)-loaded, glyceryl monooleyl ether-based liquid crystalline nanoparticles (LCNs) with a hexagonal structure was examined by synchrotron X-ray diffraction and confocal laser scanning mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f64fd012196b5e3e4a82c10b81dd87cc
https://doi.org/10.1016/j.ijpharm.2018.11.031
https://doi.org/10.1016/j.ijpharm.2018.11.031
Autor:
Yoshiyuki Kagawa, Shun Fujimori, Tomoka Fushimi, Ichiro Hatta, Hiyori Fujino, Tomonobu Uchino, Daichi Kamiya, Miyuki Asano, Yasunori Miyazaki, Rie Suzuki
Publikováno v:
International Journal of Pharmaceutics. 548:192-205
Phospholipid nanoparticles (PNs) encapsulating vitamin C and E derivatives, 3-O-cetyl ascorbic acid (CA) and tocopherol acetate (TA), respectively, were examined using the film rehydration and extrusion method. PN formulations (TA-Cassome) were prepa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe9e029b9a339a0f068703e29e353951
https://doi.org/10.1016/j.ijpharm.2018.06.030
https://doi.org/10.1016/j.ijpharm.2018.06.030