Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Ichiro, Takada"'
Autor:
Yura Jotatsu, Jack L. Arbiser, Michika Moriwaki, Yuto Hirata, Shunya Takeda, Ichiro Takada, Kuan-Chou Chen, Shian-Ying Sung, Katsumi Shigemura
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Bladder cancer treatments are highly aggressive and have strong side effects. Safer and more effective treatments are needed. In this study, Dibenzolium (DIB), a potent NADPH oxidase inhibitor, was evaluated for its anti-tumor effects. KK-47
Externí odkaz:
https://doaj.org/article/44d61d8107d84aa5bfdcf985415548ae
Autor:
Sayuri Takahashi, Ichiro Takada, Kenichi Hashimoto, Atsushi Yokoyama, Tohru Nakagawa, Makoto Makishima, Haruki Kume
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Molecular targeted therapy using poly (ADP-ribose) polymerase inhibitors has improved survival in patients with castration-resistant prostate cancer (CRPC). However, this approach is only effective in patients with specific genetic mutations
Externí odkaz:
https://doaj.org/article/42d3466dc5294d4fa00de1c0b2ab069a
Autor:
Sayuri Takahashi, Ichiro Takada
Publikováno v:
Asian Journal of Andrology, Vol 25, Iss 2, Pp 158-165 (2023)
Prostate cancer is one of the most common diseases in men worldwide. Surgery, radiation therapy, and hormonal therapy are effective treatments for early-stage prostate cancer. However, the development of castration-resistant prostate cancer has incre
Externí odkaz:
https://doaj.org/article/2b7e6afe2af6475d949514f4e25134fc
Autor:
Ichiro, Takada, Shinya, Hidano, Sayuri, Takahashi, Kaori, Yanaka, Hidesato, Ogawa, Megumi, Tsuchiya, Atsushi, Yokoyama, Shingo, Sato, Hiroki, Ochi, Tohru, Nakagawa, Takashi, Kobayashi, Shinichi, Nakagawa, Makoto, Makishima
Publikováno v:
The Journal of biological chemistry. 298(9)
Ess2, also known as Dgcr14, is a transcriptional co-regulator of CD4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9dffa88fc79492194bbe9c594b4e7e56
https://pubmed.ncbi.nlm.nih.gov/35933014
https://pubmed.ncbi.nlm.nih.gov/35933014
Autor:
Takehiko Kamijo, Tsugumichi Koshinaga, Miki Ohira, Ichiro Takada, Hiroki Nagase, Makoto Makishima, Yusuke Suenaga, Shinichi Kobayashi, Kiyohiro Ando, Satoshi Wada, Verna Cázares-Ordoñez
Publikováno v:
Cancer science. 113(2)
Checkpoint kinase 1 (CHK1) plays a key role in genome surveillance and integrity throughout the cell cycle. Selective inhibitors of CHK1 (CHK1i) are undergoing clinical evaluation for various human malignancies, including neuroblastoma. In this study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94afc204aa6d4778e8ad766d5a452c06
https://pubmed.ncbi.nlm.nih.gov/34807483
https://pubmed.ncbi.nlm.nih.gov/34807483
Publikováno v:
Journal of Pharmacological Sciences, Vol 97, Iss 2, Pp 184-189 (2005)
Peroxisome proliferator-activated receptor gamma (PPARγ) is a ligand-dependent nuclear receptor and regulates adipogenesis and fat metabolism. PPARγ is activated by fatty acid derivatives and some synthetic compounds such as the thiazolidinediones.
Externí odkaz:
https://doaj.org/article/416bae1593704679b79140d6af13ac35
Autor:
Ichiro Takada, Makoto Makishima
Publikováno v:
Expert Opinion on Therapeutic Patents. 30:1-13
Introduction: Peroxisome proliferator-activated receptors (PPARs), PPARα, PPARδ, and PPARγ, play an important role in the regulation of various physiological processes, specifically lipid and energy metabolism and immunity. PPARα agonists (fibrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c40ffd41ba19003250c9ac04f4a26fd0
https://doi.org/10.1080/13543776.2020.1703952
https://doi.org/10.1080/13543776.2020.1703952
Autor:
Ichiro Takada, Shinya Hidano, Sayuri Takahashi, Kaori Yanaka, Hidesato Ogawa, Megumi Tsuchiya, Atsushi Yokoyama, Shingo Sato, Hiroki Ochi, Tohru Nakagawa, Takashi Kobayashi, Shinichi Nakagawa, Makoto Makishima
Publikováno v:
Journal of Biological Chemistry. 298:102342
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69e53e5a9e71819f5f28980d3c65fadf
https://doi.org/10.1016/j.jbc.2022.102342
https://doi.org/10.1016/j.jbc.2022.102342
Autor:
Ichiro Takada, Mime Kobayashi
Publikováno v:
PPAR Research, Vol 2013 (2013)
While an understanding of lipid metabolism in chickens is critical for a further improvement of food production, there are few studies concerning differences in lipid metabolism mechanisms between chickens and other species at a molecular level. Chic
Externí odkaz:
https://doaj.org/article/026463712065425ea8ae62013401f556
Publikováno v:
PPAR Research, Vol 2012 (2012)
Recent studies have revealed that PPARγ’s transactivation function is regulated by extracellular signals. In particular, cytokines and Wnt family proteins suppress the ligand-inducible transactivation function of PPARγ and attenuate adipogenesis/
Externí odkaz:
https://doaj.org/article/67bae86a4d0340eca7c1e5ae132dcac1